AXSM

Axsome Therapeutics, Inc.

56
Fundamentals72/ 100
Valuation50/ 100
Upside potential58/ 100
Risk potential23/ 100

AXSM offers stronger fundamentals, but that advantage does not outweigh its weaker overall profile.

UNH

UnitedHealth Group Incorporated

62
Fundamentals51/ 100
Valuation56/ 100
Upside potential71/ 100
Risk potential15/ 100

UNH has the edge over AXSM overall, supported by stronger modeled upside and lower modeled downside.

AXSM Fundamentals

MetricStatus
Healthy
Under pressure
Under pressure
Unavailable

AXSM's revenue is currently healthy, but its profitability and cash flow are under pressure. There isn't enough data to rate its balance sheet.

UNH Fundamentals

MetricStatus
Stable
Stable
Healthy
Healthy

UNH's cash flow and balance sheet are currently healthy, and its revenue and profitability are stable.

AXSM PE Valuation

AXSM has no meaningful PE right now: it lost money over the past year. If it returns to profit as analysts expect, today's price would be 83x next year's earnings.

UNH PE Valuation

CHEAPFAIREXPENSIVE10x21x31x42x
CHEAPFAIREXPENSIVE10x21x31x42x
LevelPEPriceVs current
Forward18x$405—
Cheap19x$325-20%
Fair23x$410+1.2%
Current23x$405—
Expensive30x$526+30%

Historical ranges are pointers, not guarantees.

UNH's PE is in its fair range at 23x. If earnings grow as analysts expect, today's price would be 18x next year's earnings, in its cheap range.

AXSM Forward outlook

MetricOutlook
--
Returning to profit
Strong growth
Strongly improving
Limited
Low

AXSM has the edge over UNH on the outlook, with more favorable revenue expectations.

UNH Forward outlook

MetricOutlook
Strongly improving
Strong growth
Stable
Improving
Moderate
Low

Analysts expect UNH's earnings to grow and its profitability to improve, with its revenue holding steady. However, they disagree widely on these estimates.

AXSM Risk to reward

ScenarioChangePrice
Upside+32%$191.10
Downside-23%$111.05

Calculated from the latest close: $144.37 on Nov 12.

AXSM trails UNH on modeled risk to reward, with less potential upside and more potential downside.

UNH Risk to reward

ScenarioChangePrice
Upside+36%$550.65
Downside-15%$346.07

Calculated from the latest close: $405.13 on Nov 12.

UNH has a better modeled risk to reward balance than AXSM, with more potential upside and less potential downside.

AXSM Earnings Per Share

Q4 2023: $-5.27Q1 2024: $-6.45Q2 2024: $-6.58Q3 2024: $-6.60Q4 2024: $-5.99Q1 2025: $-5.77Q2 2025: $-5.07Q3 2025: $-4.67Q4 2025: $-3.68Q1 2026: $-3.72Q2 2026: $-3.74Q3 2026: $-3.05Forward: $1.74
Q4 2023: $-5.27Q1 2024: $-6.45Q2 2024: $-6.58Q3 2024: $-6.60Q4 2024: $-5.99Q1 2025: $-5.77Q2 2025: $-5.07Q3 2025: $-4.67Q4 2025: $-3.68Q1 2026: $-3.72Q2 2026: $-3.74Q3 2026: $-3.05Forward: $1.74
QuarterTTM EPSYoY
Forward$1.74—
Q3 2026-$3.05+$1.62
Q2 2026-$3.74+$1.33
Q1 2026-$3.72+$2.05
Q4 2025-$3.68+$2.31
Q3 2025-$4.67+$1.93
Q2 2025-$5.07+$1.51
Q1 2025-$5.77+$0.68
Q4 2024-$5.99-$0.72

AXSM is still losing money, but far less than before: $3.05 per share over the past year, against $6.60 at its worst in late 2024.

UNH Earnings Per Share

Q4 2023: $23.86Q1 2024: $16.38Q2 2024: $15.10Q3 2024: $15.37Q4 2024: $15.51Q1 2025: $23.89Q2 2025: $23.09Q3 2025: $19.17Q4 2025: $13.23Q1 2026: $13.28Q2 2026: $15.58Q3 2026: $17.55Forward: $22.65
Q4 2023: $23.86Q1 2024: $16.38Q2 2024: $15.10Q3 2024: $15.37Q4 2024: $15.51Q1 2025: $23.89Q2 2025: $23.09Q3 2025: $19.17Q4 2025: $13.23Q1 2026: $13.28Q2 2026: $15.58Q3 2026: $17.55Forward: $22.65
QuarterTTM EPSYoY
Forward$22.65+29%
Q3 2026$17.55-8.5%
Q2 2026$15.58-33%
Q1 2026$13.28-44%
Q4 2025$13.23-15%
Q3 2025$19.17+25%
Q2 2025$23.09+53%
Q1 2025$23.89+46%
Q4 2024$15.51-35%

UNH has the edge over AXSM on earnings quality, reporting a profit while its opponent remains loss making.

AXSM Quarterly Revenue

Q4 2023: $72MQ1 2024: $75MQ2 2024: $87MQ3 2024: $105MQ4 2024: $119MQ1 2025: $121MQ2 2025: $150MQ3 2025: $171MQ4 2025: $196MQ1 2026: $191MQ2 2026: $218MQ3 2026: $260M
Q4 2023: $72MQ1 2024: $75MQ2 2024: $87MQ3 2024: $105MQ4 2024: $119MQ1 2025: $121MQ2 2025: $150MQ3 2025: $171MQ4 2025: $196MQ1 2026: $191MQ2 2026: $218MQ3 2026: $260M
QuarterRevenueYoY
Q3 2026$259.7M+52%
Q2 2026$218.4M+46%
Q1 2026$191.2M+57%
Q4 2025$196M+65%
Q3 2025$171M+63%
Q2 2025$150M+72%
Q1 2025$121.5M+62%
Q4 2024$118.8M+66%

AXSM has the edge over UNH on sales, with more consistent year-over-year improvement.

UNH Quarterly Revenue

Q4 2023: $94.4BQ1 2024: $99.8BQ2 2024: $98.9BQ3 2024: $101BQ4 2024: $101BQ1 2025: $110BQ2 2025: $112BQ3 2025: $113BQ4 2025: $113BQ1 2026: $112BQ2 2026: $112BQ3 2026: $113B
Q4 2023: $94.4BQ1 2024: $99.8BQ2 2024: $98.9BQ3 2024: $101BQ4 2024: $101BQ1 2025: $110BQ2 2025: $112BQ3 2025: $113BQ4 2025: $113BQ1 2026: $112BQ2 2026: $112BQ3 2026: $113B
QuarterRevenueYoY
Q3 2026$112.7B-0.4%
Q2 2026$112B+0.4%
Q1 2026$111.7B+2%
Q4 2025$113.2B+12%
Q3 2025$113.2B+12%
Q2 2025$111.6B+13%
Q1 2025$109.6B+9.8%
Q4 2024$100.8B+6.8%

UNH's revenue has held roughly level: $113B last quarter, about level with the same quarter a year ago.

AXSM Free Cash Flow

Q4 2023: −$30MQ1 2024: −$54MQ2 2024: −$30MQ3 2024: −$19MQ4 2024: −$26MQ1 2025: −$44MQ2 2025: −$32MQ3 2025: $988,000Q4 2025: −$19MQ1 2026: −$21MQ2 2026: −$33MQ3 2026: −$10M
Q4 2023: −$30MQ1 2024: −$54MQ2 2024: −$30MQ3 2024: −$19MQ4 2024: −$26MQ1 2025: −$44MQ2 2025: −$32MQ3 2025: $988,000Q4 2025: −$19MQ1 2026: −$21MQ2 2026: −$33MQ3 2026: −$10M
QuarterFree cash flowYoY
Q3 2026-$9.7M-1078%
Q2 2026-$33.4M-$966K
Q1 2026-$20.8M+$22.9M
Q4 2025-$18.7M+$7.5M
Q3 2025$988K+$19.7M
Q2 2025-$32.4M-$2.3M
Q1 2025-$43.7M+$9.9M
Q4 2024-$26.2M+$4.1M

AXSM has burned cash in almost every quarter: −$83M over the past year, against −$101M the year before.

UNH Free Cash Flow

Q4 2023: −$6.2BQ1 2024: $401MQ2 2024: $5.9BQ3 2024: $13BQ4 2024: $1.5BQ1 2025: $4.6BQ2 2025: $6.3BQ3 2025: $5.1BQ4 2025: $160MQ1 2026: $8.1BQ2 2026: $10.3BQ3 2026: $4.3B
Q4 2023: −$6.2BQ1 2024: $401MQ2 2024: $5.9BQ3 2024: $13BQ4 2024: $1.5BQ1 2025: $4.6BQ2 2025: $6.3BQ3 2025: $5.1BQ4 2025: $160MQ1 2026: $8.1BQ2 2026: $10.3BQ3 2026: $4.3B
QuarterFree cash flowYoY
Q3 2026$4.3B-16%
Q2 2026$10.3B+63%
Q1 2026$8.1B+79%
Q4 2025$160M-89%
Q3 2025$5.1B-61%
Q2 2025$6.3B+6.9%
Q1 2025$4.6B+1037%
Q4 2024$1.5B+$7.6B

UNH has the edge over AXSM on cash generation, producing positive trailing cash flow while its opponent burns cash.

AXSM Total Shares

Q4 2023: 45MQ1 2024: 47MQ2 2024: 48MQ3 2024: 48MQ4 2024: 48MQ1 2025: 49MQ2 2025: 49MQ3 2025: 50MQ4 2025: 50MQ1 2026: 51MQ2 2026: 52MQ3 2026: 52M
Q4 2023: 45MQ1 2024: 47MQ2 2024: 48MQ3 2024: 48MQ4 2024: 48MQ1 2025: 49MQ2 2025: 49MQ3 2025: 50MQ4 2025: 50MQ1 2026: 51MQ2 2026: 52MQ3 2026: 52M
PeriodChange %Net change
Quarterly+1.2%+645K shares
1 year+4.8%+2.4M shares
3 years+11%+5.3M shares
5 years+39%+14.8M shares
Available history+54%+18.4M shares

AXSM has 52M diluted shares, up 4.8% from a year ago.

UNH Total Shares

Q4 2023: 938MQ1 2024: 922MQ2 2024: 928MQ3 2024: 930MQ4 2024: 929MQ1 2025: 918MQ2 2025: 910MQ3 2025: 908MQ4 2025: 911MQ1 2026: 910MQ2 2026: 906MQ3 2026: 902M
Q4 2023: 938MQ1 2024: 922MQ2 2024: 928MQ3 2024: 930MQ4 2024: 929MQ1 2025: 918MQ2 2025: 910MQ3 2025: 908MQ4 2025: 911MQ1 2026: 910MQ2 2026: 906MQ3 2026: 902M
PeriodChange %Net change
Quarterly-0.4%-4M shares
1 year-0.7%-6M shares
3 years-3.6%-34M shares
5 years-5.5%-53M shares
Available history-6.6%-64M shares

UNH has the edge over AXSM on shareholder dilution, with a more favorable share count trend.

AXSM Net Leverage

AXSM's operating earnings (EBITDA) were negative over the past year, so its debt can't be measured against them.

UNH Net Leverage

Q4 2023: 1.0xQ1 2024: 1.3xQ2 2024: 1.4xQ3 2024: 1.3xQ4 2024: 1.4xQ1 2025: 1.3xQ2 2025: 1.5xQ3 2025: 1.7xQ4 2025: 2.3xQ1 2026: 2.2xQ2 2026: 1.7xQ3 2026: 1.7x
Q4 2023: 1.0xQ1 2024: 1.3xQ2 2024: 1.4xQ3 2024: 1.3xQ4 2024: 1.4xQ1 2025: 1.3xQ2 2025: 1.5xQ3 2025: 1.7xQ4 2025: 2.3xQ1 2026: 2.2xQ2 2026: 1.7xQ3 2026: 1.7x
QuarterNet LeverageStatus
Q3 20261.7xHealthy
Q2 20261.7xHealthy
Q1 20262.2xModerate
Q4 20252.3xModerate
Q3 20251.7xHealthy
Q2 20251.5xHealthy
Q1 20251.3xHealthy
Q4 20241.4xHealthy

UNH's net debt is about 1.7 years of its operating earnings (EBITDA), about the same as a year ago.

AXSM Weekly Momentum

MetricValueStatus
RSI33.6Neutral
Stochastic13.4Oversold

AXSM's weekly RSI is 34 (neutral) and its Stochastic is 13 (oversold).

UNH Weekly Momentum

MetricValueStatus
RSI56.4Neutral
Stochastic60.0Neutral

UNH's weekly RSI is 56 (neutral) and its Stochastic is 60 (neutral).

AXSM PE vs Healthcare Sector

AXSM has no meaningful PE right now: it lost money over the past year.

UNH PE vs Healthcare Sector

MetricUNHSector medianRelative
PE23x26x11% below
PE %472918 pts above

UNH is trading at 23x earnings, a 11% discount to the Healthcare sector's median of 26x.

AXSM Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$158.38.8% below
20 week MA$195.126% below
50 week MA$191.325% below
100 week MA$152.45.3% below
200 week MA$114.926% above

AXSM has fallen below most of its moving averages, though it's still 26% above its 200-week average.

UNH Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$394.22.8% above
20 week MA$400.51.2% above
50 week MA$361.212% above
100 week MA$376.07.8% above
200 week MA$446.69.3% below

UNH has the edge over AXSM on trend strength, trading above more of its moving averages.

AXSM Yearly ROI

YearStart priceEnd priceROI
2020$102.0$84.9-17%
2021$84.9$38.5-55%
2022$38.5$73.8+92%
2023$73.8$79.6+7.9%
2024$79.6$86.7+8.9%
2025$86.7$152.1+75%
2026 YTD$152.1$144.4-5.1%

AXSM has finished higher in four of the last six years, two of them by more than 50%. It's down 5.1% so far in 2026.

UNH Yearly ROI

YearStart priceEnd priceROI
2020$296.0$340.8+15%
2021$340.8$495.4+45%
2022$495.4$531.3+7.3%
2023$531.3$526.5-0.9%
2024$526.5$510.0-3.1%
2025$510.0$331.8-35%
2026 YTD$331.8$405.1+22%

UNH has the edge over AXSM on returns for 2026, with the stronger performance.

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