AXSM

Axsome Therapeutics, Inc.

56
Fundamentals72/ 100
Valuation50/ 100
Upside potential58/ 100
Risk potential23/ 100

AXSM lost money over the past year, so it has no meaningful PE right now. Analysts expect earnings to recover and profitability to improve, though they disagree widely on how much.

AXSM Fundamentals

MetricStatus
Healthy
Under pressure
Under pressure
Unavailable

AXSM's revenue is currently healthy, but its profitability and cash flow are under pressure. There isn't enough data to rate its balance sheet.

AXSM PE Valuation

AXSM has no meaningful PE right now: it lost money over the past year. If it returns to profit as analysts expect, today's price would be 83x next year's earnings.

AXSM Forward outlook

MetricOutlook
--
Returning to profit
Strong growth
Strongly improving
Limited
Low

Analysts expect AXSM to return to profit, with revenue growing. However, they disagree widely on these estimates.

AXSM Risk to reward

ScenarioChangePrice
Upside+32%$191.10
Downside-23%$111.05

Calculated from the latest close: $144.37 on Nov 12.

AXSM's one-year upside scenario is somewhat larger than its downside: +32% against −23%.

AXSM Earnings Per Share

Q4 2023: $-5.27Q1 2024: $-6.45Q2 2024: $-6.58Q3 2024: $-6.60Q4 2024: $-5.99Q1 2025: $-5.77Q2 2025: $-5.07Q3 2025: $-4.67Q4 2025: $-3.68Q1 2026: $-3.72Q2 2026: $-3.74Q3 2026: $-3.05Forward: $1.74
Q4 2023: $-5.27Q1 2024: $-6.45Q2 2024: $-6.58Q3 2024: $-6.60Q4 2024: $-5.99Q1 2025: $-5.77Q2 2025: $-5.07Q3 2025: $-4.67Q4 2025: $-3.68Q1 2026: $-3.72Q2 2026: $-3.74Q3 2026: $-3.05Forward: $1.74
QuarterTTM EPSYoY
Forward$1.74—
Q3 2026-$3.05+$1.62
Q2 2026-$3.74+$1.33
Q1 2026-$3.72+$2.05
Q4 2025-$3.68+$2.31
Q3 2025-$4.67+$1.93
Q2 2025-$5.07+$1.51
Q1 2025-$5.77+$0.68
Q4 2024-$5.99-$0.72

AXSM is still losing money, but far less than before: $3.05 per share over the past year, against $6.60 at its worst in late 2024.

AXSM Quarterly Revenue

Q4 2023: $72MQ1 2024: $75MQ2 2024: $87MQ3 2024: $105MQ4 2024: $119MQ1 2025: $121MQ2 2025: $150MQ3 2025: $171MQ4 2025: $196MQ1 2026: $191MQ2 2026: $218MQ3 2026: $260M
Q4 2023: $72MQ1 2024: $75MQ2 2024: $87MQ3 2024: $105MQ4 2024: $119MQ1 2025: $121MQ2 2025: $150MQ3 2025: $171MQ4 2025: $196MQ1 2026: $191MQ2 2026: $218MQ3 2026: $260M
QuarterRevenueYoY
Q3 2026$259.7M+52%
Q2 2026$218.4M+46%
Q1 2026$191.2M+57%
Q4 2025$196M+65%
Q3 2025$171M+63%
Q2 2025$150M+72%
Q1 2025$121.5M+62%
Q4 2024$118.8M+66%

AXSM's revenue has grown year over year for 10 quarters in a row: $260M last quarter, up 52% from the same quarter a year ago.

AXSM Free Cash Flow

Q4 2023: −$30MQ1 2024: −$54MQ2 2024: −$30MQ3 2024: −$19MQ4 2024: −$26MQ1 2025: −$44MQ2 2025: −$32MQ3 2025: $988,000Q4 2025: −$19MQ1 2026: −$21MQ2 2026: −$33MQ3 2026: −$10M
Q4 2023: −$30MQ1 2024: −$54MQ2 2024: −$30MQ3 2024: −$19MQ4 2024: −$26MQ1 2025: −$44MQ2 2025: −$32MQ3 2025: $988,000Q4 2025: −$19MQ1 2026: −$21MQ2 2026: −$33MQ3 2026: −$10M
QuarterFree cash flowYoY
Q3 2026-$9.7M-1078%
Q2 2026-$33.4M-$966K
Q1 2026-$20.8M+$22.9M
Q4 2025-$18.7M+$7.5M
Q3 2025$988K+$19.7M
Q2 2025-$32.4M-$2.3M
Q1 2025-$43.7M+$9.9M
Q4 2024-$26.2M+$4.1M

AXSM has burned cash in almost every quarter: −$83M over the past year, against −$101M the year before.

AXSM Total Shares

Q4 2023: 45MQ1 2024: 47MQ2 2024: 48MQ3 2024: 48MQ4 2024: 48MQ1 2025: 49MQ2 2025: 49MQ3 2025: 50MQ4 2025: 50MQ1 2026: 51MQ2 2026: 52MQ3 2026: 52M
Q4 2023: 45MQ1 2024: 47MQ2 2024: 48MQ3 2024: 48MQ4 2024: 48MQ1 2025: 49MQ2 2025: 49MQ3 2025: 50MQ4 2025: 50MQ1 2026: 51MQ2 2026: 52MQ3 2026: 52M
PeriodChange %Net change
Quarterly+1.2%+645K shares
1 year+4.8%+2.4M shares
3 years+11%+5.3M shares
5 years+39%+14.8M shares
Available history+54%+18.4M shares

AXSM has 52M diluted shares, up 4.8% from a year ago.

AXSM Net Leverage

AXSM's operating earnings (EBITDA) were negative over the past year, so its debt can't be measured against them.

AXSM Weekly Momentum

MetricValueStatus
RSI33.6Neutral
Stochastic13.4Oversold

AXSM's weekly RSI is 34 (neutral) and its Stochastic is 13 (oversold).

AXSM PE vs Healthcare Sector

AXSM has no meaningful PE right now: it lost money over the past year.

AXSM Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$158.38.8% below
20 week MA$195.126% below
50 week MA$191.325% below
100 week MA$152.45.3% below
200 week MA$114.926% above

AXSM has fallen below most of its moving averages, though it's still 26% above its 200-week average.

AXSM Yearly ROI

YearStart priceEnd priceROI
2020$102.0$84.9-17%
2021$84.9$38.5-55%
2022$38.5$73.8+92%
2023$73.8$79.6+7.9%
2024$79.6$86.7+8.9%
2025$86.7$152.1+75%
2026 YTD$152.1$144.4-5.1%

AXSM has finished higher in four of the last six years, two of them by more than 50%. It's down 5.1% so far in 2026.

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