ARWR

Arrowhead Pharmaceuticals, Inc.

25
Fundamentals12/ 100
Valuation50/ 100
Upside potential59/ 100
Risk potential30/ 100

ARWR trails on the overall score without a compensating advantage in the available component scores.

LLY

Eli Lilly and Company

78
Fundamentals85/ 100
Valuation62/ 100
Upside potential72/ 100
Risk potential15/ 100

LLY has the edge over ARWR overall, supported by stronger fundamentals and lower modeled downside.

ARWR Fundamentals

MetricStatus
Weak
Weak
Weak
Strong

ARWR's balance sheet is currently strong, but its revenue, profitability and cash flow are weak.

LLY Fundamentals

MetricStatus
Healthy
Strong
Strong
Healthy

LLY's revenue, profitability, cash flow and balance sheet are all currently healthy.

ARWR PE Valuation

ARWR has no meaningful PE right now: it lost money over the past year.

LLY PE Valuation

CHEAPFAIREXPENSIVE37x74x111x147x
CHEAPFAIREXPENSIVE37x74x111x147x
LevelPEPriceVs current
Cheap27x$845-41%
Forward30x$1,427—
Current46x$1,427—
Fair48x$1,466+2.7%
Expensive85x$2,612+83%

Historical ranges are pointers, not guarantees.

LLY's PE is in its fair range at 46x. If earnings grow as analysts expect, today's price would be 30x next year's earnings, in its cheap range.

ARWR Forward outlook

MetricOutlook
--
Losses growing
Strong decline
--
Limited
Low

Analysts expect ARWR's losses to grow, with revenue declining. However, they disagree widely on these estimates.

LLY Forward outlook

MetricOutlook
Strongly improving
Strong growth
Strong growth
Strongly improving
Limited
Moderate

Analysts expect strong earnings and revenue growth for LLY, with profitability improving.

ARWR Risk to reward

ScenarioChangePrice
Upside+43%$67.51
Downside-30%$32.85

Calculated from the latest close: $47.15 on Nov 12.

ARWR trails LLY on modeled risk to reward, with less potential upside relative to its potential downside.

LLY Risk to reward

ScenarioChangePrice
Upside+39%$1,988.49
Downside-15%$1,209.08

Calculated from the latest close: $1,427.28 on Nov 12.

LLY has a better modeled risk to reward balance than ARWR, with more potential upside relative to its potential downside.

ARWR Earnings Per Share

Q4 2023: $-2.77Q1 2024: $-4.24Q2 2024: $-4.66Q3 2024: $-5.00Q4 2024: $-5.15Q1 2025: $-1.38Q2 2025: $-1.26Q3 2025: $-0.01Q4 2025: $1.60Q1 2026: $-2.08Q2 2026: $-2.18Q3 2026: $-5.11
Q4 2023: $-2.77Q1 2024: $-4.24Q2 2024: $-4.66Q3 2024: $-5.00Q4 2024: $-5.15Q1 2025: $-1.38Q2 2025: $-1.26Q3 2025: $-0.01Q4 2025: $1.60Q1 2026: $-2.08Q2 2026: $-2.18Q3 2026: $-5.11
QuarterTTM EPSYoY
Q3 2026-$5.11-$5.10
Q2 2026-$2.18-$0.92
Q1 2026-$2.08-$0.70
Q4 2025$1.60+$6.75
Q3 2025-$0.01+$4.99
Q2 2025-$1.26+$3.40
Q1 2025-$1.38+$2.86
Q4 2024-$5.15-$2.38

ARWR lost $5.11 per share over the past year, and its loss has widened in each of the last three quarters.

LLY Earnings Per Share

Q4 2023: $5.80Q1 2024: $6.79Q2 2024: $8.12Q3 2024: $9.25Q4 2024: $11.71Q1 2025: $12.29Q2 2025: $15.30Q3 2025: $20.44Q4 2025: $22.95Q1 2026: $28.15Q2 2026: $29.80Q3 2026: $30.81Forward: $46.82
Q4 2023: $5.80Q1 2024: $6.79Q2 2024: $8.12Q3 2024: $9.25Q4 2024: $11.71Q1 2025: $12.29Q2 2025: $15.30Q3 2025: $20.44Q4 2025: $22.95Q1 2026: $28.15Q2 2026: $29.80Q3 2026: $30.81Forward: $46.82
QuarterTTM EPSYoY
Forward$46.82+52%
Q3 2026$30.81+51%
Q2 2026$29.80+95%
Q1 2026$28.15+129%
Q4 2025$22.95+96%
Q3 2025$20.44+121%
Q2 2025$15.30+88%
Q1 2025$12.29+81%
Q4 2024$11.71+102%

LLY has the edge over ARWR on earnings quality, reporting a profit while its opponent remains loss making.

ARWR Quarterly Revenue

Q4 2023: $4MQ1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $3MQ1 2025: $543MQ2 2025: $28MQ3 2025: $256MQ4 2025: $264MQ1 2026: $74MQ2 2026: $75MQ3 2026: $38M
Q4 2023: $4MQ1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $3MQ1 2025: $543MQ2 2025: $28MQ3 2025: $256MQ4 2025: $264MQ1 2026: $74MQ2 2026: $75MQ3 2026: $38M
QuarterRevenueYoY
Q3 2026$37.8M-85%
Q2 2026$75.3M+171%
Q1 2026$73.7M-86%
Q4 2025$264M+10461%
Q4 2024$2.5M-30%
Q4 2023$3.6M-94%
Q3 2023$16.1M-49%
Q2 2023$15.8M-51%

ARWR's revenue has slid since its 2025 peak: $38M last quarter, down 85% from the same quarter a year ago.

LLY Quarterly Revenue

Q4 2023: $9.4BQ1 2024: $8.8BQ2 2024: $11.3BQ3 2024: $11.4BQ4 2024: $13.5BQ1 2025: $12.7BQ2 2025: $15.6BQ3 2025: $17.6BQ4 2025: $19.3BQ1 2026: $19.8BQ2 2026: $23BQ3 2026: $24.4B
Q4 2023: $9.4BQ1 2024: $8.8BQ2 2024: $11.3BQ3 2024: $11.4BQ4 2024: $13.5BQ1 2025: $12.7BQ2 2025: $15.6BQ3 2025: $17.6BQ4 2025: $19.3BQ1 2026: $19.8BQ2 2026: $23BQ3 2026: $24.4B
QuarterRevenueYoY
Q3 2026$24.4B+39%
Q2 2026$23B+48%
Q1 2026$19.8B+56%
Q4 2025$19.3B+43%
Q3 2025$17.6B+54%
Q2 2025$15.6B+38%
Q1 2025$12.7B+45%
Q4 2024$13.5B+45%

LLY has the edge over ARWR on sales, with more consistent year-over-year improvement.

ARWR Free Cash Flow

Q4 2023: −$186MQ1 2024: −$126MQ2 2024: −$130MQ3 2024: −$162MQ4 2024: −$154MQ1 2025: $455MQ2 2025: −$157MQ3 2025: $13MQ4 2025: $11MQ1 2026: $82MQ2 2026: −$181MQ3 2026: −$196M
Q4 2023: −$186MQ1 2024: −$126MQ2 2024: −$130MQ3 2024: −$162MQ4 2024: −$154MQ1 2025: $455MQ2 2025: −$157MQ3 2025: $13MQ4 2025: $11MQ1 2026: $82MQ2 2026: −$181MQ3 2026: −$196M
QuarterFree cash flowYoY
Q3 2026-$195.8M-1606%
Q2 2026-$181.3M-$24.2M
Q1 2026$81.9M-82%
Q4 2025$11.3M+$165.1M
Q3 2025$13M+$174.5M
Q2 2025-$157.1M-$27.2M
Q1 2025$454.8M+$581.2M
Q4 2024-$153.8M+$32.7M

ARWR has burned cash in most quarters: −$284M over the past year, against $157M the year before.

LLY Free Cash Flow

Q4 2023: −$1.4BQ1 2024: $180MQ2 2024: $241MQ3 2024: $2.4BQ4 2024: $978MQ1 2025: $156MQ2 2025: $1.4BQ3 2025: $6.7BQ4 2025: $678MQ1 2026: $3BQ2 2026: $7.8BQ3 2026: $8.2B
Q4 2023: −$1.4BQ1 2024: $180MQ2 2024: $241MQ3 2024: $2.4BQ4 2024: $978MQ1 2025: $156MQ2 2025: $1.4BQ3 2025: $6.7BQ4 2025: $678MQ1 2026: $3BQ2 2026: $7.8BQ3 2026: $8.2B
QuarterFree cash flowYoY
Q3 2026$8.2B+22%
Q2 2026$7.8B+458%
Q1 2026$3B+1826%
Q4 2025$677.9M-31%
Q3 2025$6.7B+186%
Q2 2025$1.4B+476%
Q1 2025$156.1M-13%
Q4 2024$977.8M+$2.4B

LLY has the edge over ARWR on cash generation, producing positive trailing cash flow while its opponent burns cash.

ARWR Total Shares

Q4 2023: 107MQ1 2024: 123MQ2 2024: 124MQ3 2024: 120MQ4 2024: 125MQ1 2025: 134MQ2 2025: 139MQ3 2025: 134MQ4 2025: 141MQ1 2026: 142MQ2 2026: 143MQ3 2026: 142M
Q4 2023: 107MQ1 2024: 123MQ2 2024: 124MQ3 2024: 120MQ4 2024: 125MQ1 2025: 134MQ2 2025: 139MQ3 2025: 134MQ4 2025: 141MQ1 2026: 142MQ2 2026: 143MQ3 2026: 142M
PeriodChange %Net change
Quarterly-1.2%-1.7M shares
1 year+5.9%+7.9M shares
3 years+33%+34.9M shares
5 years+37%+37.9M shares
Available history+46%+44.5M shares

ARWR has 142M diluted shares, up 5.9% from a year ago.

LLY Total Shares

Q4 2023: 903MQ1 2024: 904MQ2 2024: 904MQ3 2024: 905MQ4 2024: 904MQ1 2025: 901MQ2 2025: 900MQ3 2025: 899MQ4 2025: 899MQ1 2026: 896MQ2 2026: 894MQ3 2026: 893M
Q4 2023: 903MQ1 2024: 904MQ2 2024: 904MQ3 2024: 905MQ4 2024: 904MQ1 2025: 901MQ2 2025: 900MQ3 2025: 899MQ4 2025: 899MQ1 2026: 896MQ2 2026: 894MQ3 2026: 893M
PeriodChange %Net change
Quarterly0%-300K shares
1 year-0.6%-5.4M shares
3 years-0.7%-6.4M shares
5 years-1.9%-17.4M shares
Available history-4.5%-42.3M shares

LLY has the edge over ARWR on shareholder dilution, with a more favorable share count trend.

ARWR Net Leverage

Q3 2025: 0.2xQ4 2025: 0.0x
Q3 2025: 0.2xQ4 2025: 0.0x
QuarterNet LeverageStatus
Q4 20250.0xVery low
Q3 20250.2xVery low
Q1 2020-51.3xNet Cash
Q4 2019-9.3xNet Cash

ARWR has more cash than debt.

LLY Net Leverage

Q4 2023: 2.8xQ1 2024: 2.6xQ2 2024: 2.4xQ3 2024: 2.4xQ4 2024: 2.1xQ1 2025: 2.3xQ2 2025: 2.0xQ3 2025: 1.3xQ4 2025: 1.3xQ1 2026: 1.2xQ2 2026: 1.3xQ3 2026: 1.2x
Q4 2023: 2.8xQ1 2024: 2.6xQ2 2024: 2.4xQ3 2024: 2.4xQ4 2024: 2.1xQ1 2025: 2.3xQ2 2025: 2.0xQ3 2025: 1.3xQ4 2025: 1.3xQ1 2026: 1.2xQ2 2026: 1.3xQ3 2026: 1.2x
QuarterNet LeverageStatus
Q3 20261.2xHealthy
Q2 20261.3xHealthy
Q1 20261.2xHealthy
Q4 20251.3xHealthy
Q3 20251.3xHealthy
Q2 20252.0xHealthy
Q1 20252.3xModerate
Q4 20242.1xModerate

LLY's net debt is about 1.2 years of its operating earnings (EBITDA), about the same as a year ago.

ARWR Weekly Momentum

MetricValueStatus
RSI29.8Oversold
Stochastic6.6Oversold

ARWR's weekly RSI is 30 (oversold) and its Stochastic is 7 (oversold).

LLY Weekly Momentum

MetricValueStatus
RSI68.3Neutral
Stochastic84.1Overbought

LLY's weekly RSI is 68 (neutral) and its Stochastic is 84 (overbought).

ARWR PE vs Healthcare Sector

MetricARWRSector medianRelative
PEN/A26x—

ARWR has no meaningful PE right now: it lost money over the past year.

LLY PE vs Healthcare Sector

MetricLLYSector medianRelative
PE46x26x79% above
PE %482919 pts above

LLY is trading at 46x earnings, a 79% premium to the Healthcare sector's median of 26x.

ARWR Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$59.020% below
20 week MA$73.035% below
50 week MA$70.033% below
100 week MA$46.12.3% above
200 week MA$37.127% above

ARWR has pulled back, but its long-term trend is still up: it's below its 8-, 20- and 50-week averages, but 27% above its 200-week average.

LLY Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$1,279.412% above
20 week MA$1,218.817% above
50 week MA$1,102.229% above
100 week MA$954.150% above
200 week MA$797.579% above

LLY has the edge over ARWR on trend strength, trading above more of its moving averages.

ARWR Yearly ROI

YearStart priceEnd priceROI
2020$64.9$84.2+30%
2021$84.2$70.3-17%
2022$70.3$38.3-45%
2023$38.3$30.6-20%
2024$30.6$19.0-38%
2025$19.0$70.2+270%
2026 YTD$70.2$47.2-33%

ARWR's yearly returns have swung widely, from +270% in 2025 to −45% in 2022. It's down 33% so far in 2026.

LLY Yearly ROI

YearStart priceEnd priceROI
2020$131.5$166.7+27%
2021$166.7$273.1+64%
2022$273.1$367.9+35%
2023$367.9$582.9+58%
2024$582.9$783.2+34%
2025$783.2$1,077.8+38%
2026 YTD$1,077.8$1,427.3+32%

LLY has the edge over ARWR on returns for 2026, with the stronger performance.

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