ARWR

Arrowhead Pharmaceuticals, Inc.

25
Fundamentals12/ 100
Valuation50/ 100
Upside potential59/ 100
Risk potential30/ 100

ARWR lost money over the past year, so it has no meaningful PE right now. Analysts expect losses to grow, though they disagree widely on how much.

ARWR Fundamentals

MetricStatus
Weak
Weak
Weak
Strong

ARWR's balance sheet is currently strong, but its revenue, profitability and cash flow are weak.

ARWR PE Valuation

ARWR has no meaningful PE right now: it lost money over the past year.

ARWR Forward outlook

MetricOutlook
--
Losses growing
Strong decline
--
Limited
Low

Analysts expect ARWR's losses to grow, with revenue declining. However, they disagree widely on these estimates.

ARWR Risk to reward

ScenarioChangePrice
Upside+43%$67.51
Downside-30%$32.85

Calculated from the latest close: $47.15 on Nov 12.

ARWR's one-year upside scenario is somewhat larger than its downside: +43% against −30%.

ARWR Earnings Per Share

Q4 2023: $-2.77Q1 2024: $-4.24Q2 2024: $-4.66Q3 2024: $-5.00Q4 2024: $-5.15Q1 2025: $-1.38Q2 2025: $-1.26Q3 2025: $-0.01Q4 2025: $1.60Q1 2026: $-2.08Q2 2026: $-2.18Q3 2026: $-5.11
Q4 2023: $-2.77Q1 2024: $-4.24Q2 2024: $-4.66Q3 2024: $-5.00Q4 2024: $-5.15Q1 2025: $-1.38Q2 2025: $-1.26Q3 2025: $-0.01Q4 2025: $1.60Q1 2026: $-2.08Q2 2026: $-2.18Q3 2026: $-5.11
QuarterTTM EPSYoY
Q3 2026-$5.11-$5.10
Q2 2026-$2.18-$0.92
Q1 2026-$2.08-$0.70
Q4 2025$1.60+$6.75
Q3 2025-$0.01+$4.99
Q2 2025-$1.26+$3.40
Q1 2025-$1.38+$2.86
Q4 2024-$5.15-$2.38

ARWR lost $5.11 per share over the past year, and its loss has widened in each of the last three quarters.

ARWR Quarterly Revenue

Q4 2023: $4MQ1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $3MQ1 2025: $543MQ2 2025: $28MQ3 2025: $256MQ4 2025: $264MQ1 2026: $74MQ2 2026: $75MQ3 2026: $38M
Q4 2023: $4MQ1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $3MQ1 2025: $543MQ2 2025: $28MQ3 2025: $256MQ4 2025: $264MQ1 2026: $74MQ2 2026: $75MQ3 2026: $38M
QuarterRevenueYoY
Q3 2026$37.8M-85%
Q2 2026$75.3M+171%
Q1 2026$73.7M-86%
Q4 2025$264M+10461%
Q4 2024$2.5M-30%
Q4 2023$3.6M-94%
Q3 2023$16.1M-49%
Q2 2023$15.8M-51%

ARWR's revenue has slid since its 2025 peak: $38M last quarter, down 85% from the same quarter a year ago.

ARWR Free Cash Flow

Q4 2023: −$186MQ1 2024: −$126MQ2 2024: −$130MQ3 2024: −$162MQ4 2024: −$154MQ1 2025: $455MQ2 2025: −$157MQ3 2025: $13MQ4 2025: $11MQ1 2026: $82MQ2 2026: −$181MQ3 2026: −$196M
Q4 2023: −$186MQ1 2024: −$126MQ2 2024: −$130MQ3 2024: −$162MQ4 2024: −$154MQ1 2025: $455MQ2 2025: −$157MQ3 2025: $13MQ4 2025: $11MQ1 2026: $82MQ2 2026: −$181MQ3 2026: −$196M
QuarterFree cash flowYoY
Q3 2026-$195.8M-1606%
Q2 2026-$181.3M-$24.2M
Q1 2026$81.9M-82%
Q4 2025$11.3M+$165.1M
Q3 2025$13M+$174.5M
Q2 2025-$157.1M-$27.2M
Q1 2025$454.8M+$581.2M
Q4 2024-$153.8M+$32.7M

ARWR has burned cash in most quarters: −$284M over the past year, against $157M the year before.

ARWR Total Shares

Q4 2023: 107MQ1 2024: 123MQ2 2024: 124MQ3 2024: 120MQ4 2024: 125MQ1 2025: 134MQ2 2025: 139MQ3 2025: 134MQ4 2025: 141MQ1 2026: 142MQ2 2026: 143MQ3 2026: 142M
Q4 2023: 107MQ1 2024: 123MQ2 2024: 124MQ3 2024: 120MQ4 2024: 125MQ1 2025: 134MQ2 2025: 139MQ3 2025: 134MQ4 2025: 141MQ1 2026: 142MQ2 2026: 143MQ3 2026: 142M
PeriodChange %Net change
Quarterly-1.2%-1.7M shares
1 year+5.9%+7.9M shares
3 years+33%+34.9M shares
5 years+37%+37.9M shares
Available history+46%+44.5M shares

ARWR has 142M diluted shares, up 5.9% from a year ago.

ARWR Net Leverage

Q3 2025: 0.2xQ4 2025: 0.0x
Q3 2025: 0.2xQ4 2025: 0.0x
QuarterNet LeverageStatus
Q4 20250.0xVery low
Q3 20250.2xVery low
Q1 2020-51.3xNet Cash
Q4 2019-9.3xNet Cash

ARWR has more cash than debt.

ARWR Weekly Momentum

MetricValueStatus
RSI29.8Oversold
Stochastic6.6Oversold

ARWR's weekly RSI is 30 (oversold) and its Stochastic is 7 (oversold).

ARWR PE vs Healthcare Sector

MetricARWRSector medianRelative
PEN/A26x—

ARWR has no meaningful PE right now: it lost money over the past year.

ARWR Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$59.020% below
20 week MA$73.035% below
50 week MA$70.033% below
100 week MA$46.12.3% above
200 week MA$37.127% above

ARWR has pulled back, but its long-term trend is still up: it's below its 8-, 20- and 50-week averages, but 27% above its 200-week average.

ARWR Yearly ROI

YearStart priceEnd priceROI
2020$64.9$84.2+30%
2021$84.2$70.3-17%
2022$70.3$38.3-45%
2023$38.3$30.6-20%
2024$30.6$19.0-38%
2025$19.0$70.2+270%
2026 YTD$70.2$47.2-33%

ARWR's yearly returns have swung widely, from +270% in 2025 to −45% in 2022. It's down 33% so far in 2026.

Give your agent the market.

Get API key