AGIO
Agios Pharmaceuticals, Inc.
There isn't enough reported data to score AGIO yet.
UNH
UnitedHealth Group Incorporated
UNH's fundamentals are mixed: free cash flow grew 31%, but earnings per share fell 8.5%. At 23x earnings, it's trading right at its usual valuation. Analysts expect strong earnings growth, though they disagree widely on how much.
AGIO Fundamentals
| Metric | Status |
|---|---|
| Strong | |
| Under pressure | |
| Under pressure | |
| Unavailable |
AGIO's revenue is currently strong, but its profitability and cash flow are under pressure. There isn't enough data to rate its balance sheet.
UNH Fundamentals
| Metric | Status |
|---|---|
| Stable | |
| Stable | |
| Healthy | |
| Healthy |
UNH's cash flow and balance sheet are currently healthy, and its revenue and profitability are stable.
AGIO PE Valuation
AGIO has no meaningful PE right now: it lost money over the past year.
UNH PE Valuation
| Level | PE | Price | Vs current |
|---|---|---|---|
| Forward | 18x | $405 | — |
| Cheap | 19x | $325 | -20% |
| Fair | 23x | $410 | +1.2% |
| Current | 23x | $405 | — |
| Expensive | 30x | $526 | +30% |
Historical ranges are pointers, not guarantees.
UNH's PE is in its fair range at 23x. If earnings grow as analysts expect, today's price would be 18x next year's earnings, in its cheap range.
AGIO Forward outlook
| Metric | Outlook |
|---|---|
| -- | |
| Losses shrinking | |
| Strong growth | |
| -- | |
| Limited | |
| Low |
Analysts expect AGIO's losses to shrink, with revenue growing. However, they disagree widely on these estimates.
UNH Forward outlook
| Metric | Outlook |
|---|---|
| Strongly improving | |
| Strong growth | |
| Stable | |
| Improving | |
| Moderate | |
| Low |
Analysts expect UNH's earnings to grow and its profitability to improve, with its revenue holding steady. However, they disagree widely on these estimates.
AGIO Earnings Per Share
| Quarter | TTM EPS | YoY |
|---|---|---|
| Q3 2026 | -$6.33 | +$0.37 |
| Q2 2026 | -$7.02 | -162% |
| Q1 2026 | -$7.26 | -163% |
| Q4 2025 | -$7.12 | -161% |
| Q3 2025 | -$6.70 | -159% |
| Q2 2025 | $11.30 | +$17.79 |
| Q1 2025 | $11.54 | +$17.85 |
| Q4 2024 | $11.64 | +$17.97 |
AGIO lost $6.33 per share over the past year, about the same as its loss the year before.
UNH Earnings Per Share
| Quarter | TTM EPS | YoY |
|---|---|---|
| Forward | $22.65 | +29% |
| Q3 2026 | $17.55 | -8.5% |
| Q2 2026 | $15.58 | -33% |
| Q1 2026 | $13.28 | -44% |
| Q4 2025 | $13.23 | -15% |
| Q3 2025 | $19.17 | +25% |
| Q2 2025 | $23.09 | +53% |
| Q1 2025 | $23.89 | +46% |
| Q4 2024 | $15.51 | -35% |
UNH has the edge over AGIO on earnings quality, reporting a profit while its opponent remains loss making.
AGIO Quarterly Revenue
| Quarter | Revenue | YoY |
|---|---|---|
| Q3 2026 | $55.4M | +330% |
| Q2 2026 | $44.7M | +259% |
| Q1 2026 | $20.7M | +138% |
| Q4 2025 | $20M | +86% |
| Q3 2025 | $12.9M | +44% |
| Q2 2025 | $12.5M | +45% |
| Q1 2025 | $8.7M | +6.6% |
| Q4 2024 | $10.7M | +51% |
AGIO has the edge over UNH on sales, with more consistent year-over-year improvement.
| Quarter | Margin | YoY |
|---|---|---|
| Q3 2026 | -139% | +768 points |
| Q2 2026 | -247% | +773 points |
| Q1 2026 | -530% | +692 points |
| Q4 2025 | -609% | +556 points |
| Q3 2025 | -907% | +240 points |
| Q2 2025 | -1020% | +208 points |
| Q1 2025 | -1222% | -98 points |
| Q4 2024 | -1165% | +331 points |
AGIO's operating margin was −139% last quarter, up 768 points from the same quarter a year ago, near the top of its range since 2019.
UNH Quarterly Revenue
| Quarter | Revenue | YoY |
|---|---|---|
| Q3 2026 | $112.7B | -0.4% |
| Q2 2026 | $112B | +0.4% |
| Q1 2026 | $111.7B | +2% |
| Q4 2025 | $113.2B | +12% |
| Q3 2025 | $113.2B | +12% |
| Q2 2025 | $111.6B | +13% |
| Q1 2025 | $109.6B | +9.8% |
| Q4 2024 | $100.8B | +6.8% |
UNH's revenue has held roughly level: $113B last quarter, about level with the same quarter a year ago.
| Quarter | Margin | YoY |
|---|---|---|
| Q3 2026 | 5.8% | +2 points |
| Q2 2026 | 7.1% | +2.5 points |
| Q1 2026 | 8.1% | -0.3 points |
| Q4 2025 | 0.3% | -7.4 points |
| Q3 2025 | 3.8% | -4.8 points |
| Q2 2025 | 4.6% | -3.4 points |
| Q1 2025 | 8.3% | +0.4 points |
| Q4 2024 | 7.7% | -0.4 points |
UNH has the edge over AGIO on profitability, with a higher operating margin.
AGIO Free Cash Flow
| Quarter | Free cash flow | YoY |
|---|---|---|
| Q3 2026 | -$60.4M | +$29.3M |
| Q2 2026 | -$58.5M | +$19.5M |
| Q1 2026 | -$119.7M | -$7.4M |
| Q4 2025 | -$97.3M | +$36.8M |
| Q3 2025 | -$89.7M | -$5.1M |
| Q2 2025 | -$78M | -$5.3M |
| Q1 2025 | -$112.3M | -$12.2M |
| Q4 2024 | -$134.1M | -$61.4M |
AGIO has burned cash in almost every quarter: −$336M over the past year, against −$414M the year before.
UNH Free Cash Flow
| Quarter | Free cash flow | YoY |
|---|---|---|
| Q3 2026 | $4.3B | -16% |
| Q2 2026 | $10.3B | +63% |
| Q1 2026 | $8.1B | +79% |
| Q4 2025 | $160M | -89% |
| Q3 2025 | $5.1B | -61% |
| Q2 2025 | $6.3B | +6.9% |
| Q1 2025 | $4.6B | +1037% |
| Q4 2024 | $1.5B | +$7.6B |
UNH has the edge over AGIO on cash generation, producing positive trailing cash flow while its opponent burns cash.
AGIO Total Shares
| Period | Change % | Net change |
|---|---|---|
| Quarterly | +0.4% | +219K shares |
| 1 year | +2.7% | +1.6M shares |
| 3 years | +7% | +3.9M shares |
| 5 years | +4.7% | +2.7M shares |
| Available history | -0.5% | -287K shares |
AGIO has 60M diluted shares, up 2.7% from a year ago.
| Quarter | Spent |
|---|---|
| Q4 2022 | — |
| Q3 2022 | — |
| Q4 2021 | $19M |
| Q3 2021 | $254.4M |
UNH Total Shares
| Period | Change % | Net change |
|---|---|---|
| Quarterly | -0.4% | -4M shares |
| 1 year | -0.7% | -6M shares |
| 3 years | -3.6% | -34M shares |
| 5 years | -5.5% | -53M shares |
| Available history | -6.6% | -64M shares |
UNH has the edge over AGIO on shareholder dilution, with a more favorable share count trend.
| Quarter | Spent |
|---|---|
| Q3 2026 | $3.4B |
| Q2 2026 | $1.6B |
| Q1 2026 | — |
| Q4 2025 | — |
| Q3 2025 | — |
| Q2 2025 | $2.5B |
| Q1 2025 | $3B |
| Q4 2024 | $5B |
UNH spent $5B buying back its own shares over the past year, down 52% from the year before.
AGIO Net Leverage
AGIO's operating earnings (EBITDA) were negative over the past year, so its debt can't be measured against them.
UNH Net Leverage
| Quarter | Net Leverage | Status |
|---|---|---|
| Q3 2026 | 1.7x | Healthy |
| Q2 2026 | 1.7x | Healthy |
| Q1 2026 | 2.2x | Moderate |
| Q4 2025 | 2.3x | Moderate |
| Q3 2025 | 1.7x | Healthy |
| Q2 2025 | 1.5x | Healthy |
| Q1 2025 | 1.3x | Healthy |
| Q4 2024 | 1.4x | Healthy |
UNH's net debt is about 1.7 years of its operating earnings (EBITDA), about the same as a year ago.
AGIO Weekly Momentum
| Metric | Value | Status |
|---|---|---|
| RSI | 48.7 | Neutral |
| Stochastic | 23.0 | Neutral |
AGIO's weekly RSI is 49 (neutral) and its Stochastic is 23 (neutral).
UNH Weekly Momentum
| Metric | Value | Status |
|---|---|---|
| RSI | 56.4 | Neutral |
| Stochastic | 60.0 | Neutral |
UNH's weekly RSI is 56 (neutral) and its Stochastic is 60 (neutral).
AGIO PE vs Healthcare Sector
| Metric | AGIO | Sector median | Relative |
|---|---|---|---|
| PE | N/A | 26x | — |
AGIO has no meaningful PE right now: it lost money over the past year.
UNH PE vs Healthcare Sector
| Metric | UNH | Sector median | Relative |
|---|---|---|---|
| PE | 23x | 26x | 11% below |
| PE % | 47 | 29 | 18 pts above |
UNH is trading at 23x earnings, a 11% discount to the Healthcare sector's median of 26x.
AGIO Weekly Moving Averages
| Moving average | MA price | Relative |
|---|---|---|
| 8 week MA | $32.0 | 0.8% below |
| 20 week MA | $33.7 | 5.6% below |
| 50 week MA | $30.9 | 2.7% above |
| 100 week MA | $32.8 | 3.1% below |
| 200 week MA | $32.4 | 1.9% below |
AGIO's trend is mixed: it's above one of its five weekly moving averages, and 1.9% below its 200-week average.
UNH Weekly Moving Averages
| Moving average | MA price | Relative |
|---|---|---|
| 8 week MA | $394.2 | 2.8% above |
| 20 week MA | $400.5 | 1.2% above |
| 50 week MA | $361.2 | 12% above |
| 100 week MA | $376.0 | 7.8% above |
| 200 week MA | $446.6 | 9.3% below |
UNH has the edge over AGIO on trend strength, trading above more of its moving averages.
AGIO Yearly ROI
| Year | Start price | End price | ROI |
|---|---|---|---|
| 2020 | $48.5 | $45.2 | -6.9% |
| 2021 | $45.2 | $35.8 | -21% |
| 2022 | $35.8 | $27.0 | -25% |
| 2023 | $27.0 | $22.3 | -18% |
| 2024 | $22.3 | $33.4 | +50% |
| 2025 | $33.4 | $28.0 | -16% |
| 2026 YTD | $28.0 | $31.8 | +13% |
AGIO has finished lower in five of the last six years. It's up 13% so far in 2026.
UNH Yearly ROI
| Year | Start price | End price | ROI |
|---|---|---|---|
| 2020 | $296.0 | $340.8 | +15% |
| 2021 | $340.8 | $495.4 | +45% |
| 2022 | $495.4 | $531.3 | +7.3% |
| 2023 | $531.3 | $526.5 | -0.9% |
| 2024 | $526.5 | $510.0 | -3.1% |
| 2025 | $510.0 | $331.8 | -35% |
| 2026 YTD | $331.8 | $405.1 | +22% |
UNH has the edge over AGIO on returns for 2026, with the stronger performance.