AGIO
Agios Pharmaceuticals, Inc.
There isn't enough reported data to score AGIO yet.
AGIO Fundamentals
| Metric | Status |
|---|---|
| Strong | |
| Under pressure | |
| Under pressure | |
| Unavailable |
AGIO's revenue is currently strong, but its profitability and cash flow are under pressure. There isn't enough data to rate its balance sheet.
AGIO PE Valuation
AGIO has no meaningful PE right now: it lost money over the past year.
AGIO Forward outlook
| Metric | Outlook |
|---|---|
| -- | |
| Losses shrinking | |
| Strong growth | |
| -- | |
| Limited | |
| Low |
Analysts expect AGIO's losses to shrink, with revenue growing. However, they disagree widely on these estimates.
AGIO Earnings Per Share
| Quarter | TTM EPS | YoY |
|---|---|---|
| Q3 2026 | -$6.33 | +$0.37 |
| Q2 2026 | -$7.02 | -162% |
| Q1 2026 | -$7.26 | -163% |
| Q4 2025 | -$7.12 | -161% |
| Q3 2025 | -$6.70 | -159% |
| Q2 2025 | $11.30 | +$17.79 |
| Q1 2025 | $11.54 | +$17.85 |
| Q4 2024 | $11.64 | +$17.97 |
AGIO lost $6.33 per share over the past year, about the same as its loss the year before.
AGIO Quarterly Revenue
| Quarter | Revenue | YoY |
|---|---|---|
| Q3 2026 | $55.4M | +330% |
| Q2 2026 | $44.7M | +259% |
| Q1 2026 | $20.7M | +138% |
| Q4 2025 | $20M | +86% |
| Q3 2025 | $12.9M | +44% |
| Q2 2025 | $12.5M | +45% |
| Q1 2025 | $8.7M | +6.6% |
| Q4 2024 | $10.7M | +51% |
AGIO's revenue has grown year over year for 15 quarters in a row: $55M last quarter, up 330% from the same quarter a year ago.
| Quarter | Margin | YoY |
|---|---|---|
| Q3 2026 | -139% | +768 points |
| Q2 2026 | -247% | +773 points |
| Q1 2026 | -530% | +692 points |
| Q4 2025 | -609% | +556 points |
| Q3 2025 | -907% | +240 points |
| Q2 2025 | -1020% | +208 points |
| Q1 2025 | -1222% | -98 points |
| Q4 2024 | -1165% | +331 points |
AGIO's operating margin was −139% last quarter, up 768 points from the same quarter a year ago, near the top of its range since 2019.
AGIO Free Cash Flow
| Quarter | Free cash flow | YoY |
|---|---|---|
| Q3 2026 | -$60.4M | +$29.3M |
| Q2 2026 | -$58.5M | +$19.5M |
| Q1 2026 | -$119.7M | -$7.4M |
| Q4 2025 | -$97.3M | +$36.8M |
| Q3 2025 | -$89.7M | -$5.1M |
| Q2 2025 | -$78M | -$5.3M |
| Q1 2025 | -$112.3M | -$12.2M |
| Q4 2024 | -$134.1M | -$61.4M |
AGIO has burned cash in almost every quarter: −$336M over the past year, against −$414M the year before.
AGIO Total Shares
| Period | Change % | Net change |
|---|---|---|
| Quarterly | +0.4% | +219K shares |
| 1 year | +2.7% | +1.6M shares |
| 3 years | +7% | +3.9M shares |
| 5 years | +4.7% | +2.7M shares |
| Available history | -0.5% | -287K shares |
AGIO has 60M diluted shares, up 2.7% from a year ago.
| Quarter | Spent |
|---|---|
| Q4 2022 | — |
| Q3 2022 | — |
| Q4 2021 | $19M |
| Q3 2021 | $254.4M |
AGIO Net Leverage
AGIO's operating earnings (EBITDA) were negative over the past year, so its debt can't be measured against them.
AGIO Weekly Momentum
| Metric | Value | Status |
|---|---|---|
| RSI | 48.7 | Neutral |
| Stochastic | 23.0 | Neutral |
AGIO's weekly RSI is 49 (neutral) and its Stochastic is 23 (neutral).
AGIO PE vs Healthcare Sector
| Metric | AGIO | Sector median | Relative |
|---|---|---|---|
| PE | N/A | 26x | — |
AGIO has no meaningful PE right now: it lost money over the past year.
AGIO Weekly Moving Averages
| Moving average | MA price | Relative |
|---|---|---|
| 8 week MA | $32.0 | 0.8% below |
| 20 week MA | $33.7 | 5.6% below |
| 50 week MA | $30.9 | 2.7% above |
| 100 week MA | $32.8 | 3.1% below |
| 200 week MA | $32.4 | 1.9% below |
AGIO's trend is mixed: it's above one of its five weekly moving averages, and 1.9% below its 200-week average.
AGIO Yearly ROI
| Year | Start price | End price | ROI |
|---|---|---|---|
| 2020 | $48.5 | $45.2 | -6.9% |
| 2021 | $45.2 | $35.8 | -21% |
| 2022 | $35.8 | $27.0 | -25% |
| 2023 | $27.0 | $22.3 | -18% |
| 2024 | $22.3 | $33.4 | +50% |
| 2025 | $33.4 | $28.0 | -16% |
| 2026 YTD | $28.0 | $31.8 | +13% |
AGIO has finished lower in five of the last six years. It's up 13% so far in 2026.