XLO

Xilio Therapeutics, Inc.

There isn't enough reported data to score XLO yet.

XLO Fundamentals

MetricStatus
Healthy
Under pressure
Weak
Unavailable

XLO's revenue is currently healthy, but its profitability and cash flow are under pressure. There isn't enough data to rate its balance sheet.

XLO PE Valuation

XLO has no meaningful PE right now: it lost money over the past year.

XLO Forward outlook

MetricOutlook
--
Losses shrinking
Decline
--
Limited
Low

Analysts expect XLO's losses to shrink, with revenue declining. However, they disagree widely on these estimates.

XLO Risk to reward

ScenarioChangePrice
UpsideUnknown—
DownsideUnknown—

Calculated from the latest close: $8.24 on Nov 12.

There is not enough scenario data to assess XLO's risk to reward.

XLO Earnings Per Share

Q4 2023: $-38.92Q1 2024: $-35.98Q2 2024: $-29.54Q3 2024: $-24.08
Q4 2023: $-38.92Q1 2024: $-35.98Q2 2024: $-29.54Q3 2024: $-24.08
QuarterTTM EPSYoY
Q3 2024-$24.08+$17.36
Q2 2024-$29.54+$13.44
Q1 2024-$35.98+$9.80
Q4 2023-$38.92+$6.16

XLO is still losing money, but less than at its worst: $24.08 per share over the past year, against $45.78 at its worst in early 2023.

XLO Quarterly Revenue

Q4 2023: --Q1 2024: --Q2 2024: $2MQ3 2024: $2MQ4 2024: $2MQ1 2025: $3MQ2 2025: $8MQ3 2025: $19MQ4 2025: $14MQ1 2026: $13MQ2 2026: $19MQ3 2026: $10M
Q4 2023: --Q1 2024: --Q2 2024: $2MQ3 2024: $2MQ4 2024: $2MQ1 2025: $3MQ2 2025: $8MQ3 2025: $19MQ4 2025: $14MQ1 2026: $13MQ2 2026: $19MQ3 2026: $10M
QuarterRevenueYoY
Q3 2026$10M-48%
Q2 2026$18.7M+131%
Q1 2026$12.6M+332%
Q4 2025$13.7M+694%
Q3 2025$19.1M+743%
Q2 2025$8.1M+243%

XLO's revenue is growing: $10M last quarter, down 48% from the same quarter a year ago.

XLO Free Cash Flow

Q4 2023: −$13MQ1 2024: --Q2 2024: --Q3 2024: −$14MQ4 2024: −$14MQ1 2025: $29MQ2 2025: −$15MQ3 2025: −$17MQ4 2025: −$2MQ1 2026: −$23MQ2 2026: −$19MQ3 2026: −$14M
Q4 2023: −$13MQ1 2024: --Q2 2024: --Q3 2024: −$14MQ4 2024: −$14MQ1 2025: $29MQ2 2025: −$15MQ3 2025: −$17MQ4 2025: −$2MQ1 2026: −$23MQ2 2026: −$19MQ3 2026: −$14M
QuarterFree cash flowYoY
Q3 2026-$13.9M+$3.6M
Q2 2026-$18.8M-$3.9M
Q1 2026-$22.9M-179%
Q4 2025-$2.1M+$12.1M
Q3 2025-$17.5M-$3.8M
Q4 2024-$14.2M-$736K
Q3 2024-$13.7M-$312K
Q4 2023-$13.4M+$5.3M

XLO has burned cash in almost every quarter: −$58M over the past year, against −$18M the year before.

XLO Total Shares

Q1 2024: 2MQ2 2024: 4MQ3 2024: 5MQ4 2024: 4MQ1 2025: 5MQ2 2025: 7MQ3 2025: 10MQ1 2026: 16MQ2 2026: 19MQ3 2026: 20M
Q1 2024: 2MQ2 2024: 4MQ3 2024: 5MQ4 2024: 4MQ1 2025: 5MQ2 2025: 7MQ3 2025: 10MQ1 2026: 16MQ2 2026: 19MQ3 2026: 20M
PeriodChange %Net change
Quarterly+1.5%+283K shares
1 year+186%+12.8M shares
3 years+905%+17.7M shares

XLO has 20M diluted shares, up 186% from a year ago.

XLO Net Leverage

XLO's operating earnings (EBITDA) were negative over the past year, so its debt can't be measured against them.

XLO Weekly Momentum

MetricValueStatus
RSI44.6Neutral
Stochastic43.7Neutral

XLO's weekly RSI is 45 (neutral) and its Stochastic is 44 (neutral).

XLO PE vs Healthcare Sector

XLO has no meaningful PE right now: it lost money over the past year.

XLO Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$8.513.2% below
20 week MA$8.836.7% below
50 week MA$8.614.3% below
100 week MA$9.9417% below
200 week MA$17.152% below

XLO is in a downtrend: it's below all five of its weekly moving averages, and 52% below its 200-week average.

XLO Yearly ROI

YearStart priceEnd priceROI
2021$224.0$224.00%
2022$224.0$32.9-85%
2023$32.9$7.70-77%
2024$7.70$13.6+77%
2025$13.6$9.27-32%
2026 YTD$9.27$8.24-11%

XLO has finished lower in four of the last five years. It's down 11% so far in 2026.

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