SPRO

Spero Therapeutics, Inc.

There isn't enough reported data to score SPRO yet.

UNH

UnitedHealth Group Incorporated

62
Fundamentals51/ 100
Valuation56/ 100
Upside potential71/ 100
Risk potential15/ 100

UNH's fundamentals are mixed: free cash flow grew 31%, but earnings per share fell 8.5%. At 23x earnings, it's trading right at its usual valuation. Analysts expect strong earnings growth, though they disagree widely on how much.

SPRO Fundamentals

MetricStatus
Under pressure
Stable
Weak
Strong

SPRO's balance sheet is currently strong, and its profitability is stable, but its revenue and cash flow are under pressure.

UNH Fundamentals

MetricStatus
Stable
Stable
Healthy
Healthy

UNH's cash flow and balance sheet are currently healthy, and its revenue and profitability are stable.

SPRO PE Valuation

SPRO has no meaningful PE right now: it lost money over the past year.

UNH PE Valuation

CHEAPFAIREXPENSIVE10x21x31x42x
CHEAPFAIREXPENSIVE10x21x31x42x
LevelPEPriceVs current
Forward18x$405—
Cheap19x$325-20%
Fair23x$410+1.2%
Current23x$405—
Expensive30x$526+30%

Historical ranges are pointers, not guarantees.

UNH's PE is in its fair range at 23x. If earnings grow as analysts expect, today's price would be 18x next year's earnings, in its cheap range.

SPRO Forward outlook

MetricOutlook
--
Losses shrinking
--
--
Limited
High

Analysts expect SPRO's losses to shrink, with revenue holding steady.

UNH Forward outlook

MetricOutlook
Strongly improving
Strong growth
Stable
Improving
Moderate
Low

Analysts expect UNH's earnings to grow and its profitability to improve, with its revenue holding steady. However, they disagree widely on these estimates.

SPRO Risk to reward

ScenarioChangePrice
UpsideUnknown—
DownsideUnknown—

Calculated from the latest close: $1.00 on Nov 12.

There is not enough scenario data to compare SPRO and UNH's risk to reward.

UNH Risk to reward

ScenarioChangePrice
Upside+36%$550.65
Downside-15%$346.07

Calculated from the latest close: $405.13 on Nov 12.

There is not enough scenario data to compare SPRO and UNH's risk to reward.

SPRO Earnings Per Share

Q4 2023: $0.43Q1 2024: $0.44Q2 2024: $0.34Q3 2024: $0.08Q4 2024: $-1.27Q1 2025: $-1.28Q2 2025: $-0.98Q3 2025: $-0.79Q4 2025: $0.15Q1 2026: $0.27Q2 2026: $0.14Q3 2026: $-0.49
Q4 2023: $0.43Q1 2024: $0.44Q2 2024: $0.34Q3 2024: $0.08Q4 2024: $-1.27Q1 2025: $-1.28Q2 2025: $-0.98Q3 2025: $-0.79Q4 2025: $0.15Q1 2026: $0.27Q2 2026: $0.14Q3 2026: $-0.49
QuarterTTM EPSYoY
Q3 2026-$0.49+$0.30
Q2 2026$0.14+$1.12
Q1 2026$0.27+$1.55
Q4 2025$0.15+$1.42
Q3 2025-$0.79-1088%
Q2 2025-$0.98-388%
Q1 2025-$1.28-391%
Q4 2024-$1.27-395%

SPRO is still losing money, but far less than before: $0.49 per share over the past year, against $4.33 at its worst in mid-2020.

UNH Earnings Per Share

Q4 2023: $23.86Q1 2024: $16.38Q2 2024: $15.10Q3 2024: $15.37Q4 2024: $15.51Q1 2025: $23.89Q2 2025: $23.09Q3 2025: $19.17Q4 2025: $13.23Q1 2026: $13.28Q2 2026: $15.58Q3 2026: $17.55Forward: $22.65
Q4 2023: $23.86Q1 2024: $16.38Q2 2024: $15.10Q3 2024: $15.37Q4 2024: $15.51Q1 2025: $23.89Q2 2025: $23.09Q3 2025: $19.17Q4 2025: $13.23Q1 2026: $13.28Q2 2026: $15.58Q3 2026: $17.55Forward: $22.65
QuarterTTM EPSYoY
Forward$22.65+29%
Q3 2026$17.55-8.5%
Q2 2026$15.58-33%
Q1 2026$13.28-44%
Q4 2025$13.23-15%
Q3 2025$19.17+25%
Q2 2025$23.09+53%
Q1 2025$23.89+46%
Q4 2024$15.51-35%

UNH has the edge over SPRO on earnings quality, reporting a profit while its opponent remains loss making.

SPRO Quarterly Revenue

Q4 2023: $74MQ1 2024: $9MQ2 2024: $10MQ3 2024: $13MQ4 2024: $15MQ1 2025: $6MQ2 2025: $14MQ3 2025: $5MQ4 2025: $41MQ1 2026: $258,000Q2 2026: $0Q3 2026: $0
Q4 2023: $74MQ1 2024: $9MQ2 2024: $10MQ3 2024: $13MQ4 2024: $15MQ1 2025: $6MQ2 2025: $14MQ3 2025: $5MQ4 2025: $41MQ1 2026: $258,000Q2 2026: $0Q3 2026: $0
QuarterRevenueYoY
Q1 2026$258K-96%
Q4 2025$41.3M+175%
Q3 2025$5.4M-60%
Q2 2025$14.2M+39%
Q1 2025$5.9M-37%
Q4 2024$15M-80%
Q3 2024$13.5M-47%
Q2 2024$10.2M+275%

SPRO's revenue fell from its 2023 peak and has held roughly level since: $0 last quarter, down 100% from the same quarter a year ago.

UNH Quarterly Revenue

Q4 2023: $94.4BQ1 2024: $99.8BQ2 2024: $98.9BQ3 2024: $101BQ4 2024: $101BQ1 2025: $110BQ2 2025: $112BQ3 2025: $113BQ4 2025: $113BQ1 2026: $112BQ2 2026: $112BQ3 2026: $113B
Q4 2023: $94.4BQ1 2024: $99.8BQ2 2024: $98.9BQ3 2024: $101BQ4 2024: $101BQ1 2025: $110BQ2 2025: $112BQ3 2025: $113BQ4 2025: $113BQ1 2026: $112BQ2 2026: $112BQ3 2026: $113B
QuarterRevenueYoY
Q3 2026$112.7B-0.4%
Q2 2026$112B+0.4%
Q1 2026$111.7B+2%
Q4 2025$113.2B+12%
Q3 2025$113.2B+12%
Q2 2025$111.6B+13%
Q1 2025$109.6B+9.8%
Q4 2024$100.8B+6.8%

UNH has the edge over SPRO on sales, with more consistent year-over-year improvement.

SPRO Free Cash Flow

Q4 2023: −$17MQ1 2024: $6MQ2 2024: −$19MQ3 2024: $13MQ4 2024: −$23MQ1 2025: −$4MQ2 2025: −$18MQ3 2025: $17MQ4 2025: −$8MQ1 2026: $16MQ2 2026: −$5MQ3 2026: −$43M
Q4 2023: −$17MQ1 2024: $6MQ2 2024: −$19MQ3 2024: $13MQ4 2024: −$23MQ1 2025: −$4MQ2 2025: −$18MQ3 2025: $17MQ4 2025: −$8MQ1 2026: $16MQ2 2026: −$5MQ3 2026: −$43M
QuarterFree cash flowYoY
Q3 2026-$42.6M-345%
Q2 2026-$5.4M+$12.3M
Q1 2026$15.9M+$19.9M
Q4 2025-$8.4M+$15.1M
Q3 2025$17.4M+37%
Q2 2025-$17.7M+$1.1M
Q1 2025-$4M-167%
Q4 2024-$23.4M-$5.9M

SPRO has burned cash in most quarters: −$40M over the past year, against −$28M the year before.

UNH Free Cash Flow

Q4 2023: −$6.2BQ1 2024: $401MQ2 2024: $5.9BQ3 2024: $13BQ4 2024: $1.5BQ1 2025: $4.6BQ2 2025: $6.3BQ3 2025: $5.1BQ4 2025: $160MQ1 2026: $8.1BQ2 2026: $10.3BQ3 2026: $4.3B
Q4 2023: −$6.2BQ1 2024: $401MQ2 2024: $5.9BQ3 2024: $13BQ4 2024: $1.5BQ1 2025: $4.6BQ2 2025: $6.3BQ3 2025: $5.1BQ4 2025: $160MQ1 2026: $8.1BQ2 2026: $10.3BQ3 2026: $4.3B
QuarterFree cash flowYoY
Q3 2026$4.3B-16%
Q2 2026$10.3B+63%
Q1 2026$8.1B+79%
Q4 2025$160M-89%
Q3 2025$5.1B-61%
Q2 2025$6.3B+6.9%
Q1 2025$4.6B+1037%
Q4 2024$1.5B+$7.6B

UNH has the edge over SPRO on cash generation, producing positive trailing cash flow while its opponent burns cash.

SPRO Total Shares

Q4 2023: 53MQ1 2024: 54MQ2 2024: 54MQ3 2024: 54MQ4 2024: 54MQ1 2025: 55MQ2 2025: 56MQ3 2025: 56MQ4 2025: 59MQ1 2026: 57MQ2 2026: 58MQ3 2026: 58M
Q4 2023: 53MQ1 2024: 54MQ2 2024: 54MQ3 2024: 54MQ4 2024: 54MQ1 2025: 55MQ2 2025: 56MQ3 2025: 56MQ4 2025: 59MQ1 2026: 57MQ2 2026: 58MQ3 2026: 58M
PeriodChange %Net change
Quarterly+0.4%+261K shares
1 year+3.5%+1.9M shares
3 years+10%+5.5M shares
5 years+96%+28.6M shares
Available history+206%+39.2M shares

SPRO has 58M diluted shares, up 3.5% from a year ago.

UNH Total Shares

Q4 2023: 938MQ1 2024: 922MQ2 2024: 928MQ3 2024: 930MQ4 2024: 929MQ1 2025: 918MQ2 2025: 910MQ3 2025: 908MQ4 2025: 911MQ1 2026: 910MQ2 2026: 906MQ3 2026: 902M
Q4 2023: 938MQ1 2024: 922MQ2 2024: 928MQ3 2024: 930MQ4 2024: 929MQ1 2025: 918MQ2 2025: 910MQ3 2025: 908MQ4 2025: 911MQ1 2026: 910MQ2 2026: 906MQ3 2026: 902M
PeriodChange %Net change
Quarterly-0.4%-4M shares
1 year-0.7%-6M shares
3 years-3.6%-34M shares
5 years-5.5%-53M shares
Available history-6.6%-64M shares

UNH has the edge over SPRO on shareholder dilution, with a more favorable share count trend.

SPRO Net Leverage

Q4 2023: -3.5xQ1 2024: -3.7xQ2 2024: -4.1x
Q4 2023: -3.5xQ1 2024: -3.7xQ2 2024: -4.1x
QuarterNet LeverageStatus
Q2 2024-4.1xNet Cash
Q1 2024-3.7xNet Cash
Q4 2023-3.5xNet Cash

SPRO has more cash than debt.

UNH Net Leverage

Q4 2023: 1.0xQ1 2024: 1.3xQ2 2024: 1.4xQ3 2024: 1.3xQ4 2024: 1.4xQ1 2025: 1.3xQ2 2025: 1.5xQ3 2025: 1.7xQ4 2025: 2.3xQ1 2026: 2.2xQ2 2026: 1.7xQ3 2026: 1.7x
Q4 2023: 1.0xQ1 2024: 1.3xQ2 2024: 1.4xQ3 2024: 1.3xQ4 2024: 1.4xQ1 2025: 1.3xQ2 2025: 1.5xQ3 2025: 1.7xQ4 2025: 2.3xQ1 2026: 2.2xQ2 2026: 1.7xQ3 2026: 1.7x
QuarterNet LeverageStatus
Q3 20261.7xHealthy
Q2 20261.7xHealthy
Q1 20262.2xModerate
Q4 20252.3xModerate
Q3 20251.7xHealthy
Q2 20251.5xHealthy
Q1 20251.3xHealthy
Q4 20241.4xHealthy

UNH's net debt is about 1.7 years of its operating earnings (EBITDA), about the same as a year ago.

SPRO Weekly Momentum

MetricValueStatus
RSI26.4Oversold
Stochastic9.2Oversold

SPRO's weekly RSI is 26 (oversold) and its Stochastic is 9 (oversold).

UNH Weekly Momentum

MetricValueStatus
RSI56.4Neutral
Stochastic60.0Neutral

UNH's weekly RSI is 56 (neutral) and its Stochastic is 60 (neutral).

SPRO PE vs Healthcare Sector

MetricSPROSector medianRelative
PE7.4x26x72% below
PE %552926 pts above

SPRO has the edge over UNH on valuation relative to its sector.

UNH PE vs Healthcare Sector

MetricUNHSector medianRelative
PE23x26x11% below
PE %472918 pts above

UNH is trading at 23x earnings, a 11% discount to the Healthcare sector's median of 26x.

SPRO Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$1.119.9% below
20 week MA$1.2822% below
50 week MA$2.0050% below
100 week MA$1.8145% below
200 week MA$1.6339% below

SPRO is in a downtrend: it's below all five of its weekly moving averages, and 39% below its 200-week average.

UNH Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$394.22.8% above
20 week MA$400.51.2% above
50 week MA$361.212% above
100 week MA$376.07.8% above
200 week MA$446.69.3% below

UNH has the edge over SPRO on trend strength, trading above more of its moving averages.

SPRO Yearly ROI

YearStart priceEnd priceROI
2020$10.4$22.0+111%
2021$22.0$14.0-36%
2022$14.0$1.59-89%
2023$1.59$1.47-7.5%
2024$1.47$1.03-30%
2025$1.03$2.32+125%
2026 YTD$2.32$1.00-57%

SPRO's yearly returns have swung widely, from +125% in 2025 to −89% in 2022. It's down 57% so far in 2026.

UNH Yearly ROI

YearStart priceEnd priceROI
2020$296.0$340.8+15%
2021$340.8$495.4+45%
2022$495.4$531.3+7.3%
2023$531.3$526.5-0.9%
2024$526.5$510.0-3.1%
2025$510.0$331.8-35%
2026 YTD$331.8$405.1+22%

UNH has the edge over SPRO on returns for 2026, with the stronger performance.

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