SEPN
Septerna, Inc.
SEPN lost money over the past year, so it has no meaningful PE right now. Analysts expect losses to grow, though they disagree widely on how much.
SEPN Fundamentals
| Metric | Status |
|---|---|
| Healthy | |
| Weak | |
| Weak | |
| Unavailable |
SEPN's revenue is currently healthy, but its profitability and cash flow are weak. There isn't enough data to rate its balance sheet.
SEPN PE Valuation
SEPN has no meaningful PE right now: it lost money over the past year.
SEPN Forward outlook
| Metric | Outlook |
|---|---|
| -- | |
| Losses growing | |
| Strong growth | |
| Strongly improving | |
| Limited | |
| Low |
Analysts expect SEPN's losses to grow, with revenue growing. However, they disagree widely on these estimates.
SEPN Earnings Per Share
SEPN has swung to a loss: it lost $1.28 per share over the past year, after a profit the year before.
SEPN Quarterly Revenue
| Quarter | Revenue | YoY |
|---|---|---|
| Q3 2026 | $18.9M | -12% |
| Q2 2026 | $26.7M | +22376% |
| Q1 2026 | $26.5M | +12011% |
| Q4 2025 | $24.1M | +11276% |
| Q3 2025 | $21.5M | +12113% |
| Q2 2025 | $119K | -68% |
| Q1 2025 | $219K | -31% |
| Q4 2024 | $212K | +80% |
SEPN's revenue is growing: $19M last quarter, down 12% from the same quarter a year ago.
| Quarter | Margin | YoY |
|---|---|---|
| Q3 2026 | -144% | -156 points |
| Q2 2026 | -63% | +24288 points |
| Q1 2026 | -50% | +11781 points |
| Q4 2025 | -66% | +11593 points |
| Q3 2025 | 12% | +12825 points |
| Q2 2025 | -24351% | -19469 points |
| Q1 2025 | -11831% | -6945 points |
| Q4 2024 | -11659% | -40742 points |
SEPN's operating margin was −144% last quarter, down 156 points from the same quarter a year ago.
SEPN Free Cash Flow
| Quarter | Free cash flow | YoY |
|---|---|---|
| Q3 2026 | -$13.9M | -108% |
| Q2 2026 | -$22.2M | -$1.8M |
| Q1 2026 | -$26.5M | -$2.7M |
| Q4 2025 | -$15.1M | +$6.5M |
| Q2 2025 | -$20.3M | -$7.2M |
| Q1 2025 | -$23.7M | -$6.3M |
| Q4 2024 | -$21.6M | -$11.5M |
SEPN has burned cash in almost every quarter: −$78M over the past year, against $103M the year before.
SEPN Total Shares
| Period | Change % | Net change |
|---|---|---|
| Quarterly | +4.2% | +1.9M shares |
| 1 year | +2.9% | +1.3M shares |
SEPN has 47M diluted shares, up 2.9% from a year ago.
| Quarter | Spent |
|---|---|
| Q2 2024 | — |
| Q1 2024 | $1,000 |
| Q4 2023 | — |
| Q3 2023 | $1,000 |
SEPN Net Leverage
SEPN's operating earnings (EBITDA) were negative over the past year, so its debt can't be measured against them.
SEPN Weekly Momentum
| Metric | Value | Status |
|---|---|---|
| RSI | 57.3 | Neutral |
| Stochastic | 62.7 | Neutral |
SEPN's weekly RSI is 57 (neutral) and its Stochastic is 63 (neutral).
SEPN PE vs Healthcare Sector
SEPN has no meaningful PE right now: it lost money over the past year.
SEPN Weekly Moving Averages
| Moving average | MA price | Relative |
|---|---|---|
| 8 week MA | $40.7 | 3% above |
| 20 week MA | $38.6 | 8.4% above |
| 50 week MA | $31.9 | 31% above |
| 100 week MA | $22.9 | 83% above |
SEPN is in an uptrend: it's above all four of its weekly moving averages, and 83% above its 100-week average.
SEPN Yearly ROI
| Year | Start price | End price | ROI |
|---|---|---|---|
| 2024 | $21.4 | $25.3 | +18% |
| 2025 | $25.3 | $28.6 | +13% |
| 2026 YTD | $28.6 | $41.9 | +46% |
SEPN has finished every year since 2024 higher, and it's up 46% so far in 2026.