PRME

Prime Medicine, Inc.

There isn't enough reported data to score PRME yet.

PRME Fundamentals

MetricStatus
Unavailable
Under pressure
Unavailable
Unavailable

PRME's profitability is currently under pressure. There isn't enough data to rate its revenue, cash flow and balance sheet.

PRME PE Valuation

PRME has no meaningful PE right now: it lost money over the past year.

PRME Forward outlook

MetricOutlook
--
Losses steady
Strong growth
--
Moderate
Low

Analysts expect PRME's revenue to grow, with its earnings and profitability holding steady. However, they disagree widely on these estimates.

PRME Risk to reward

ScenarioChangePrice
UpsideUnknown—
DownsideUnknown—

Calculated from the latest close: $3.89 on Nov 12.

There is not enough scenario data to assess PRME's risk to reward.

PRME Earnings Per Share

Q4 2023: $-2.18Q1 2024: $-2.18Q2 2024: $-2.17Q3 2024: $-2.06Q4 2024: $-1.65Q1 2025: $-1.61Q2 2025: $-1.56Q3 2025: $-1.44Q4 2025: $-1.35Q1 2026: $-1.23Q2 2026: $-1.06Q3 2026: $-0.96
Q4 2023: $-2.18Q1 2024: $-2.18Q2 2024: $-2.17Q3 2024: $-2.06Q4 2024: $-1.65Q1 2025: $-1.61Q2 2025: $-1.56Q3 2025: $-1.44Q4 2025: $-1.35Q1 2026: $-1.23Q2 2026: $-1.06Q3 2026: $-0.96
QuarterTTM EPSYoY
Q3 2026-$0.96+$0.48
Q2 2026-$1.06+$0.50
Q1 2026-$1.23+$0.38
Q4 2025-$1.35+$0.30
Q3 2025-$1.44+$0.62
Q2 2025-$1.56+$0.61
Q1 2025-$1.61+$0.57
Q4 2024-$1.65+$0.53

PRME is still losing money, but far less than before: $0.96 per share over the past year, against $3.02 at its worst in late 2022.

PRME Quarterly Revenue

Q4 2023: --Q1 2024: $591,000Q2 2024: $0Q3 2024: $209,000Q4 2024: $2MQ1 2025: $1MQ2 2025: $1MQ3 2025: $1MQ4 2025: $838,000Q1 2026: --Q2 2026: --Q3 2026: $4M
Q4 2023: --Q1 2024: $591,000Q2 2024: $0Q3 2024: $209,000Q4 2024: $2MQ1 2025: $1MQ2 2025: $1MQ3 2025: $1MQ4 2025: $838,000Q1 2026: --Q2 2026: --Q3 2026: $4M
QuarterRevenueYoY
Q3 2026$4.2M+244%
Q4 2025$838K-62%
Q3 2025$1.2M+486%
Q1 2025$1.5M+146%

PRME's revenue is growing: $4M last quarter, up 190% from the same quarter a year ago.

PRME Free Cash Flow

Q4 2023: −$46MQ1 2024: −$70MQ2 2024: −$47MQ3 2024: −$27MQ4 2024: $14MQ1 2025: −$51MQ2 2025: −$43MQ3 2025: −$35MQ4 2025: −$38MQ1 2026: −$43MQ2 2026: −$41MQ3 2026: −$37M
Q4 2023: −$46MQ1 2024: −$70MQ2 2024: −$47MQ3 2024: −$27MQ4 2024: $14MQ1 2025: −$51MQ2 2025: −$43MQ3 2025: −$35MQ4 2025: −$38MQ1 2026: −$43MQ2 2026: −$41MQ3 2026: −$37M
QuarterFree cash flowYoY
Q3 2026-$37M-$1.7M
Q2 2026-$41.1M+$1.9M
Q1 2026-$42.9M+$8.4M
Q4 2025-$37.5M-360%
Q3 2025-$35.3M-$8.1M
Q2 2025-$43M+$4.4M
Q1 2025-$51.3M+$18.8M
Q4 2024$14.5M+$60.2M

PRME has burned cash in almost every quarter: −$159M over the past year, against −$115M the year before.

PRME Total Shares

Q1 2024: 104MQ2 2024: 119MQ3 2024: 120MQ4 2024: 119MQ1 2025: 131MQ2 2025: 129MQ3 2025: 161MQ4 2025: 149MQ1 2026: 177MQ2 2026: 177MQ3 2026: 178M
Q1 2024: 104MQ2 2024: 119MQ3 2024: 120MQ4 2024: 119MQ1 2025: 131MQ2 2025: 129MQ3 2025: 161MQ4 2025: 149MQ1 2026: 177MQ2 2026: 177MQ3 2026: 178M
PeriodChange %Net change
Quarterly+0.4%+632K shares
1 year+11%+17.4M shares
3 years+97%+87.4M shares
5 years+86%+82.1M shares

PRME has 178M diluted shares, up 11% from a year ago.

PRME Net Leverage

PRME's operating earnings (EBITDA) were negative over the past year, so its debt can't be measured against them.

PRME Weekly Momentum

MetricValueStatus
RSI53.1Neutral
Stochastic53.0Neutral

PRME's weekly RSI is 53 (neutral) and its Stochastic is 53 (neutral).

PRME PE vs Healthcare Sector

PRME has no meaningful PE right now: it lost money over the past year.

PRME Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$3.782.9% above
20 week MA$3.5011% above
50 week MA$3.549.9% above
100 week MA$3.3118% above
200 week MA$6.1537% below

PRME has bounced recently, but its long-term trend is still down: it's above its 8-, 20-, 50- and 100-week averages, but 37% below its 200-week average.

PRME Yearly ROI

YearStart priceEnd priceROI
2022$15.8$17.8+13%
2023$17.8$8.86-50%
2024$8.86$2.90-67%
2025$2.90$3.50+21%
2026 YTD$3.50$3.89+11%

PRME has finished lower in two of the last four years. It's up 11% so far in 2026.

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