OPK

OPKO Health, Inc.

33
Fundamentals17/ 100
Valuation50/ 100
Upside potential56/ 100
Risk potential26/ 100

OPK trails on the overall score without a compensating advantage in the available component scores.

UNH

UnitedHealth Group Incorporated

62
Fundamentals51/ 100
Valuation56/ 100
Upside potential71/ 100
Risk potential15/ 100

UNH has the edge over OPK overall, supported by stronger fundamentals and stronger modeled upside.

OPK Fundamentals

MetricStatus
Weak
Under pressure
Weak
Strong

OPK's balance sheet is currently strong, but its revenue, profitability and cash flow are under pressure.

UNH Fundamentals

MetricStatus
Stable
Stable
Healthy
Healthy

UNH's cash flow and balance sheet are currently healthy, and its revenue and profitability are stable.

OPK PE Valuation

OPK has no meaningful PE right now: it lost money over the past year.

UNH PE Valuation

CHEAPFAIREXPENSIVE10x21x31x42x
CHEAPFAIREXPENSIVE10x21x31x42x
LevelPEPriceVs current
Forward18x$405—
Cheap19x$325-20%
Fair23x$410+1.2%
Current23x$405—
Expensive30x$526+30%

Historical ranges are pointers, not guarantees.

UNH's PE is in its fair range at 23x. If earnings grow as analysts expect, today's price would be 18x next year's earnings, in its cheap range.

OPK Forward outlook

MetricOutlook
--
Losses steady
Strong decline
Strongly weakening
Limited
Low

Analysts expect OPK's revenue and profitability to decline, with its earnings holding steady. However, they disagree widely on these estimates.

UNH Forward outlook

MetricOutlook
Strongly improving
Strong growth
Stable
Improving
Moderate
Low

UNH has the edge over OPK on the outlook, with more favorable earnings and revenue expectations.

OPK Risk to reward

ScenarioChangePrice
Upside+34%$2.23
Downside-26%$1.24

Calculated from the latest close: $1.67 on Nov 12.

OPK trails UNH on modeled risk to reward, with less potential upside and more potential downside.

UNH Risk to reward

ScenarioChangePrice
Upside+36%$550.65
Downside-15%$346.07

Calculated from the latest close: $405.13 on Nov 12.

UNH has a better modeled risk to reward balance than OPK, with more potential upside and less potential downside.

OPK Earnings Per Share

Q4 2023: $-0.25Q1 2024: $-0.35Q2 2024: $-0.33Q3 2024: $-0.19Q4 2024: $-0.09Q1 2025: $-0.07Q2 2025: $-0.25Q3 2025: $-0.25Q4 2025: $-0.30Q1 2026: $-0.27Q2 2026: $-0.09Q3 2026: $-0.19
Q4 2023: $-0.25Q1 2024: $-0.35Q2 2024: $-0.33Q3 2024: $-0.19Q4 2024: $-0.09Q1 2025: $-0.07Q2 2025: $-0.25Q3 2025: $-0.25Q4 2025: $-0.30Q1 2026: $-0.27Q2 2026: $-0.09Q3 2026: $-0.19
QuarterTTM EPSYoY
Q3 2026-$0.19+$0.06
Q2 2026-$0.09+$0.16
Q1 2026-$0.27-$0.20
Q4 2025-$0.30-$0.21
Q3 2025-$0.25-$0.06
Q2 2025-$0.25+$0.08
Q1 2025-$0.07+$0.28
Q4 2024-$0.09+$0.16

OPK is still losing money, but far less than before: $0.19 per share over the past year, against $0.53 at its worst in late 2019.

UNH Earnings Per Share

Q4 2023: $23.86Q1 2024: $16.38Q2 2024: $15.10Q3 2024: $15.37Q4 2024: $15.51Q1 2025: $23.89Q2 2025: $23.09Q3 2025: $19.17Q4 2025: $13.23Q1 2026: $13.28Q2 2026: $15.58Q3 2026: $17.55Forward: $22.65
Q4 2023: $23.86Q1 2024: $16.38Q2 2024: $15.10Q3 2024: $15.37Q4 2024: $15.51Q1 2025: $23.89Q2 2025: $23.09Q3 2025: $19.17Q4 2025: $13.23Q1 2026: $13.28Q2 2026: $15.58Q3 2026: $17.55Forward: $22.65
QuarterTTM EPSYoY
Forward$22.65+29%
Q3 2026$17.55-8.5%
Q2 2026$15.58-33%
Q1 2026$13.28-44%
Q4 2025$13.23-15%
Q3 2025$19.17+25%
Q2 2025$23.09+53%
Q1 2025$23.89+46%
Q4 2024$15.51-35%

UNH has the edge over OPK on earnings quality, reporting a profit while its opponent remains loss making.

OPK Quarterly Revenue

Q4 2023: $182MQ1 2024: $174MQ2 2024: $182MQ3 2024: $174MQ4 2024: $184MQ1 2025: $150MQ2 2025: $157MQ3 2025: $152MQ4 2025: $148MQ1 2026: $124MQ2 2026: $164MQ3 2026: $65M
Q4 2023: $182MQ1 2024: $174MQ2 2024: $182MQ3 2024: $174MQ4 2024: $184MQ1 2025: $150MQ2 2025: $157MQ3 2025: $152MQ4 2025: $148MQ1 2026: $124MQ2 2026: $164MQ3 2026: $65M
QuarterRevenueYoY
Q3 2026$65.4M-57%
Q2 2026$163.6M+4.3%
Q1 2026$124.2M-17%
Q4 2025$148.5M-19%
Q3 2025$151.7M-13%
Q2 2025$156.8M-14%
Q1 2025$150M-14%
Q4 2024$183.6M+1%

OPK's revenue has slid since its 2021 peak: $65M last quarter, down 57% from the same quarter a year ago.

UNH Quarterly Revenue

Q4 2023: $94.4BQ1 2024: $99.8BQ2 2024: $98.9BQ3 2024: $101BQ4 2024: $101BQ1 2025: $110BQ2 2025: $112BQ3 2025: $113BQ4 2025: $113BQ1 2026: $112BQ2 2026: $112BQ3 2026: $113B
Q4 2023: $94.4BQ1 2024: $99.8BQ2 2024: $98.9BQ3 2024: $101BQ4 2024: $101BQ1 2025: $110BQ2 2025: $112BQ3 2025: $113BQ4 2025: $113BQ1 2026: $112BQ2 2026: $112BQ3 2026: $113B
QuarterRevenueYoY
Q3 2026$112.7B-0.4%
Q2 2026$112B+0.4%
Q1 2026$111.7B+2%
Q4 2025$113.2B+12%
Q3 2025$113.2B+12%
Q2 2025$111.6B+13%
Q1 2025$109.6B+9.8%
Q4 2024$100.8B+6.8%

UNH has the edge over OPK on sales, with more consistent year-over-year improvement.

OPK Free Cash Flow

Q4 2023: −$41MQ1 2024: −$40MQ2 2024: −$34MQ3 2024: --Q4 2024: --Q1 2025: −$38MQ2 2025: −$87MQ3 2025: −$38MQ4 2025: −$29MQ1 2026: −$21MQ2 2026: −$47MQ3 2026: −$39M
Q4 2023: −$41MQ1 2024: −$40MQ2 2024: −$34MQ3 2024: --Q4 2024: --Q1 2025: −$38MQ2 2025: −$87MQ3 2025: −$38MQ4 2025: −$29MQ1 2026: −$21MQ2 2026: −$47MQ3 2026: −$39M
QuarterFree cash flowYoY
Q3 2026-$39.1M-$1.3M
Q2 2026-$46.5M+$40.2M
Q1 2026-$21.1M+$16.6M
Q2 2025-$86.7M-$53.1M
Q1 2025-$37.7M+$2.3M
Q2 2024-$33.7M-$27.3M
Q1 2024-$40M-$14.3M
Q4 2023-$41.3M-$3.4M

OPK has burned cash in most quarters: −$135M over the past year, against −$196M the year before.

UNH Free Cash Flow

Q4 2023: −$6.2BQ1 2024: $401MQ2 2024: $5.9BQ3 2024: $13BQ4 2024: $1.5BQ1 2025: $4.6BQ2 2025: $6.3BQ3 2025: $5.1BQ4 2025: $160MQ1 2026: $8.1BQ2 2026: $10.3BQ3 2026: $4.3B
Q4 2023: −$6.2BQ1 2024: $401MQ2 2024: $5.9BQ3 2024: $13BQ4 2024: $1.5BQ1 2025: $4.6BQ2 2025: $6.3BQ3 2025: $5.1BQ4 2025: $160MQ1 2026: $8.1BQ2 2026: $10.3BQ3 2026: $4.3B
QuarterFree cash flowYoY
Q3 2026$4.3B-16%
Q2 2026$10.3B+63%
Q1 2026$8.1B+79%
Q4 2025$160M-89%
Q3 2025$5.1B-61%
Q2 2025$6.3B+6.9%
Q1 2025$4.6B+1037%
Q4 2024$1.5B+$7.6B

UNH has the edge over OPK on cash generation, producing positive trailing cash flow while its opponent burns cash.

OPK Total Shares

Q4 2023: 752MQ1 2024: 707MQ2 2024: 697MQ3 2024: 998MQ4 2024: 694MQ1 2025: 672MQ2 2025: 788MQ3 2025: 780MQ4 2025: 751MQ1 2026: 759MQ2 2026: 755MQ3 2026: 746M
Q4 2023: 752MQ1 2024: 707MQ2 2024: 697MQ3 2024: 998MQ4 2024: 694MQ1 2025: 672MQ2 2025: 788MQ3 2025: 780MQ4 2025: 751MQ1 2026: 759MQ2 2026: 755MQ3 2026: 746M
PeriodChange %Net change
Quarterly-1.2%-8.8M shares
1 year-4.3%-33.4M shares
3 years-0.7%-5M shares
5 years+15%+94.6M shares
Available history+25%+151M shares

OPK has the edge over UNH on shareholder dilution, with a more favorable share count trend.

UNH Total Shares

Q4 2023: 938MQ1 2024: 922MQ2 2024: 928MQ3 2024: 930MQ4 2024: 929MQ1 2025: 918MQ2 2025: 910MQ3 2025: 908MQ4 2025: 911MQ1 2026: 910MQ2 2026: 906MQ3 2026: 902M
Q4 2023: 938MQ1 2024: 922MQ2 2024: 928MQ3 2024: 930MQ4 2024: 929MQ1 2025: 918MQ2 2025: 910MQ3 2025: 908MQ4 2025: 911MQ1 2026: 910MQ2 2026: 906MQ3 2026: 902M
PeriodChange %Net change
Quarterly-0.4%-4M shares
1 year-0.7%-6M shares
3 years-3.6%-34M shares
5 years-5.5%-53M shares
Available history-6.6%-64M shares

UNH has 902M diluted shares, down 0.7% from a year ago, with $5B in buybacks over the past year.

OPK Net Leverage

Q2 2026: -7.2x
Q2 2026: -7.2x
QuarterNet LeverageStatus
Q2 2026-7.2xNet Cash
Q4 20210.7xVery low
Q3 2021-0.7xNet Cash
Q2 2021-0.3xNet Cash
Q1 2021-0.4xNet Cash
Q4 20201.3xHealthy

OPK has the edge over UNH on leverage, with a lower net debt burden relative to earnings.

UNH Net Leverage

Q4 2023: 1.0xQ1 2024: 1.3xQ2 2024: 1.4xQ3 2024: 1.3xQ4 2024: 1.4xQ1 2025: 1.3xQ2 2025: 1.5xQ3 2025: 1.7xQ4 2025: 2.3xQ1 2026: 2.2xQ2 2026: 1.7xQ3 2026: 1.7x
Q4 2023: 1.0xQ1 2024: 1.3xQ2 2024: 1.4xQ3 2024: 1.3xQ4 2024: 1.4xQ1 2025: 1.3xQ2 2025: 1.5xQ3 2025: 1.7xQ4 2025: 2.3xQ1 2026: 2.2xQ2 2026: 1.7xQ3 2026: 1.7x
QuarterNet LeverageStatus
Q3 20261.7xHealthy
Q2 20261.7xHealthy
Q1 20262.2xModerate
Q4 20252.3xModerate
Q3 20251.7xHealthy
Q2 20251.5xHealthy
Q1 20251.3xHealthy
Q4 20241.4xHealthy

UNH's net debt is about 1.7 years of its operating earnings (EBITDA), about the same as a year ago.

OPK Weekly Momentum

MetricValueStatus
RSI58.9Neutral
Stochastic74.7Neutral

OPK's weekly RSI is 59 (neutral) and its Stochastic is 75 (neutral).

UNH Weekly Momentum

MetricValueStatus
RSI56.4Neutral
Stochastic60.0Neutral

UNH's weekly RSI is 56 (neutral) and its Stochastic is 60 (neutral).

OPK PE vs Healthcare Sector

MetricOPKSector medianRelative
PEN/A26x—

OPK has no meaningful PE right now: it lost money over the past year.

UNH PE vs Healthcare Sector

MetricUNHSector medianRelative
PE23x26x11% below
PE %472918 pts above

UNH is trading at 23x earnings, a 11% discount to the Healthcare sector's median of 26x.

OPK Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$1.604.4% above
20 week MA$1.5011% above
50 week MA$1.3623% above
100 week MA$1.4019% above
200 week MA$1.4218% above

OPK has the edge over UNH on trend strength, trading above more of its moving averages.

UNH Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$394.22.8% above
20 week MA$400.51.2% above
50 week MA$361.212% above
100 week MA$376.07.8% above
200 week MA$446.69.3% below

UNH has bounced recently, but its long-term trend is still down: it's above its 8-, 20-, 50- and 100-week averages, but 9.3% below its 200-week average.

OPK Yearly ROI

YearStart priceEnd priceROI
2020$1.50$4.23+182%
2021$4.23$4.77+13%
2022$4.77$1.14-76%
2023$1.14$1.51+32%
2024$1.51$1.48-2%
2025$1.48$1.29-13%
2026 YTD$1.29$1.67+29%

OPK has the edge over UNH on returns for 2026, with the stronger performance.

UNH Yearly ROI

YearStart priceEnd priceROI
2020$296.0$340.8+15%
2021$340.8$495.4+45%
2022$495.4$531.3+7.3%
2023$531.3$526.5-0.9%
2024$526.5$510.0-3.1%
2025$510.0$331.8-35%
2026 YTD$331.8$405.1+22%

UNH has finished three years in a row lower, and it's up 22% so far in 2026.

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