LLY
Eli Lilly and Company
LLY's fundamentals are strong: revenue grew 46% and it turned 23% of its revenue into free cash flow. At 46x earnings, it's trading in line with its usual 48x. Analysts expect that strong growth to continue.
SPRO
Spero Therapeutics, Inc.
There isn't enough reported data to score SPRO yet.
LLY Fundamentals
| Metric | Status |
|---|---|
| Healthy | |
| Strong | |
| Strong | |
| Healthy |
LLY's revenue, profitability, cash flow and balance sheet are all currently healthy.
SPRO Fundamentals
| Metric | Status |
|---|---|
| Under pressure | |
| Stable | |
| Weak | |
| Strong |
SPRO's balance sheet is currently strong, and its profitability is stable, but its revenue and cash flow are under pressure.
LLY PE Valuation
| Level | PE | Price | Vs current |
|---|---|---|---|
| Cheap | 27x | $845 | -41% |
| Forward | 30x | $1,427 | — |
| Current | 46x | $1,427 | — |
| Fair | 48x | $1,466 | +2.7% |
| Expensive | 85x | $2,612 | +83% |
Historical ranges are pointers, not guarantees.
LLY's PE is in its fair range at 46x. If earnings grow as analysts expect, today's price would be 30x next year's earnings, in its cheap range.
SPRO PE Valuation
SPRO has no meaningful PE right now: it lost money over the past year.
LLY Forward outlook
| Metric | Outlook |
|---|---|
| Strongly improving | |
| Strong growth | |
| Strong growth | |
| Strongly improving | |
| Limited | |
| Moderate |
Analysts expect strong earnings and revenue growth for LLY, with profitability improving.
SPRO Forward outlook
| Metric | Outlook |
|---|---|
| -- | |
| Losses shrinking | |
| -- | |
| -- | |
| Limited | |
| High |
Analysts expect SPRO's losses to shrink, with revenue holding steady.
LLY Earnings Per Share
| Quarter | TTM EPS | YoY |
|---|---|---|
| Forward | $46.82 | +52% |
| Q3 2026 | $30.81 | +51% |
| Q2 2026 | $29.80 | +95% |
| Q1 2026 | $28.15 | +129% |
| Q4 2025 | $22.95 | +96% |
| Q3 2025 | $20.44 | +121% |
| Q2 2025 | $15.30 | +88% |
| Q1 2025 | $12.29 | +81% |
| Q4 2024 | $11.71 | +102% |
LLY has the edge over SPRO on earnings quality, reporting a profit while its opponent remains loss making.
SPRO Earnings Per Share
| Quarter | TTM EPS | YoY |
|---|---|---|
| Q3 2026 | -$0.49 | +$0.30 |
| Q2 2026 | $0.14 | +$1.12 |
| Q1 2026 | $0.27 | +$1.55 |
| Q4 2025 | $0.15 | +$1.42 |
| Q3 2025 | -$0.79 | -1088% |
| Q2 2025 | -$0.98 | -388% |
| Q1 2025 | -$1.28 | -391% |
| Q4 2024 | -$1.27 | -395% |
SPRO is still losing money, but far less than before: $0.49 per share over the past year, against $4.33 at its worst in mid-2020.
LLY Quarterly Revenue
| Quarter | Revenue | YoY |
|---|---|---|
| Q3 2026 | $24.4B | +39% |
| Q2 2026 | $23B | +48% |
| Q1 2026 | $19.8B | +56% |
| Q4 2025 | $19.3B | +43% |
| Q3 2025 | $17.6B | +54% |
| Q2 2025 | $15.6B | +38% |
| Q1 2025 | $12.7B | +45% |
| Q4 2024 | $13.5B | +45% |
LLY has the edge over SPRO on sales, with more consistent year-over-year improvement.
| Quarter | Margin | YoY |
|---|---|---|
| Q3 2026 | 34% | -6.6 points |
| Q2 2026 | 40% | -3.3 points |
| Q1 2026 | 45% | +18 points |
| Q4 2025 | 43% | +5.6 points |
| Q3 2025 | 41% | +27 points |
| Q2 2025 | 44% | +12 points |
| Q1 2025 | 27% | -1.8 points |
| Q4 2024 | 37% | +10 points |
LLY's operating margin was 34% last quarter, down 6.6 points from the same quarter a year ago.
SPRO Quarterly Revenue
| Quarter | Revenue | YoY |
|---|---|---|
| Q1 2026 | $258K | -96% |
| Q4 2025 | $41.3M | +175% |
| Q3 2025 | $5.4M | -60% |
| Q2 2025 | $14.2M | +39% |
| Q1 2025 | $5.9M | -37% |
| Q4 2024 | $15M | -80% |
| Q3 2024 | $13.5M | -47% |
| Q2 2024 | $10.2M | +275% |
SPRO's revenue fell from its 2023 peak and has held roughly level since: $0 last quarter, down 100% from the same quarter a year ago.
| Quarter | Margin | YoY |
|---|---|---|
| Q1 2026 | -2922% | -2671 points |
| Q4 2025 | 76% | +221 points |
| Q3 2025 | -145% | -7.4 points |
| Q2 2025 | -17% | +170 points |
| Q1 2025 | -251% | -100 points |
| Q4 2024 | -144% | -213 points |
| Q3 2024 | -138% | -130 points |
| Q2 2024 | -187% | +288 points |
SPRO's operating margin was −2922% last quarter, down 2671 points from the same quarter a year ago, near the bottom of its range since 2019.
LLY Free Cash Flow
| Quarter | Free cash flow | YoY |
|---|---|---|
| Q3 2026 | $8.2B | +22% |
| Q2 2026 | $7.8B | +458% |
| Q1 2026 | $3B | +1826% |
| Q4 2025 | $677.9M | -31% |
| Q3 2025 | $6.7B | +186% |
| Q2 2025 | $1.4B | +476% |
| Q1 2025 | $156.1M | -13% |
| Q4 2024 | $977.8M | +$2.4B |
LLY has the edge over SPRO on cash generation, producing positive trailing cash flow while its opponent burns cash.
SPRO Free Cash Flow
| Quarter | Free cash flow | YoY |
|---|---|---|
| Q3 2026 | -$42.6M | -345% |
| Q2 2026 | -$5.4M | +$12.3M |
| Q1 2026 | $15.9M | +$19.9M |
| Q4 2025 | -$8.4M | +$15.1M |
| Q3 2025 | $17.4M | +37% |
| Q2 2025 | -$17.7M | +$1.1M |
| Q1 2025 | -$4M | -167% |
| Q4 2024 | -$23.4M | -$5.9M |
SPRO has burned cash in most quarters: −$40M over the past year, against −$28M the year before.
LLY Total Shares
| Period | Change % | Net change |
|---|---|---|
| Quarterly | 0% | -300K shares |
| 1 year | -0.6% | -5.4M shares |
| 3 years | -0.7% | -6.4M shares |
| 5 years | -1.9% | -17.4M shares |
| Available history | -4.5% | -42.3M shares |
LLY has the edge over SPRO on shareholder dilution, with a more favorable share count trend.
| Quarter | Spent |
|---|---|
| Q3 2026 | $377M |
| Q2 2026 | $1.6B |
| Q1 2026 | $2.4B |
| Q4 2025 | $1.5B |
| Q3 2025 | $708.1M |
| Q2 2025 | $692.2M |
| Q1 2025 | $1.2B |
| Q4 2024 | $2.1B |
LLY spent $5.8B buying back its own shares over the past year, up 26% from the year before.
SPRO Total Shares
| Period | Change % | Net change |
|---|---|---|
| Quarterly | +0.4% | +261K shares |
| 1 year | +3.5% | +1.9M shares |
| 3 years | +10% | +5.5M shares |
| 5 years | +96% | +28.6M shares |
| Available history | +206% | +39.2M shares |
SPRO has 58M diluted shares, up 3.5% from a year ago.
LLY Net Leverage
| Quarter | Net Leverage | Status |
|---|---|---|
| Q3 2026 | 1.2x | Healthy |
| Q2 2026 | 1.3x | Healthy |
| Q1 2026 | 1.2x | Healthy |
| Q4 2025 | 1.3x | Healthy |
| Q3 2025 | 1.3x | Healthy |
| Q2 2025 | 2.0x | Healthy |
| Q1 2025 | 2.3x | Moderate |
| Q4 2024 | 2.1x | Moderate |
LLY's net debt is about 1.2 years of its operating earnings (EBITDA), about the same as a year ago.
SPRO Net Leverage
| Quarter | Net Leverage | Status |
|---|---|---|
| Q2 2024 | -4.1x | Net Cash |
| Q1 2024 | -3.7x | Net Cash |
| Q4 2023 | -3.5x | Net Cash |
SPRO has more cash than debt.
LLY Weekly Momentum
| Metric | Value | Status |
|---|---|---|
| RSI | 68.3 | Neutral |
| Stochastic | 84.1 | Overbought |
LLY's weekly RSI is 68 (neutral) and its Stochastic is 84 (overbought).
SPRO Weekly Momentum
| Metric | Value | Status |
|---|---|---|
| RSI | 26.4 | Oversold |
| Stochastic | 9.2 | Oversold |
SPRO's weekly RSI is 26 (oversold) and its Stochastic is 9 (oversold).
LLY PE vs Healthcare Sector
| Metric | LLY | Sector median | Relative |
|---|---|---|---|
| PE | 46x | 26x | 79% above |
| PE % | 48 | 29 | 19 pts above |
LLY is trading at 46x earnings, a 79% premium to the Healthcare sector's median of 26x.
SPRO PE vs Healthcare Sector
| Metric | SPRO | Sector median | Relative |
|---|---|---|---|
| PE | 7.4x | 26x | 72% below |
| PE % | 55 | 29 | 26 pts above |
SPRO has the edge over LLY on valuation relative to its sector.
LLY Weekly Moving Averages
| Moving average | MA price | Relative |
|---|---|---|
| 8 week MA | $1,279.4 | 12% above |
| 20 week MA | $1,218.8 | 17% above |
| 50 week MA | $1,102.2 | 29% above |
| 100 week MA | $954.1 | 50% above |
| 200 week MA | $797.5 | 79% above |
LLY has the edge over SPRO on trend strength, trading above more of its moving averages.
SPRO Weekly Moving Averages
| Moving average | MA price | Relative |
|---|---|---|
| 8 week MA | $1.11 | 9.9% below |
| 20 week MA | $1.28 | 22% below |
| 50 week MA | $2.00 | 50% below |
| 100 week MA | $1.81 | 45% below |
| 200 week MA | $1.63 | 39% below |
SPRO is in a downtrend: it's below all five of its weekly moving averages, and 39% below its 200-week average.
LLY Yearly ROI
| Year | Start price | End price | ROI |
|---|---|---|---|
| 2020 | $131.5 | $166.7 | +27% |
| 2021 | $166.7 | $273.1 | +64% |
| 2022 | $273.1 | $367.9 | +35% |
| 2023 | $367.9 | $582.9 | +58% |
| 2024 | $582.9 | $783.2 | +34% |
| 2025 | $783.2 | $1,077.8 | +38% |
| 2026 YTD | $1,077.8 | $1,427.3 | +32% |
LLY has the edge over SPRO on returns for 2026, with the stronger performance.
SPRO Yearly ROI
| Year | Start price | End price | ROI |
|---|---|---|---|
| 2020 | $10.4 | $22.0 | +111% |
| 2021 | $22.0 | $14.0 | -36% |
| 2022 | $14.0 | $1.59 | -89% |
| 2023 | $1.59 | $1.47 | -7.5% |
| 2024 | $1.47 | $1.03 | -30% |
| 2025 | $1.03 | $2.32 | +125% |
| 2026 YTD | $2.32 | $1.00 | -57% |
SPRO's yearly returns have swung widely, from +125% in 2025 to −89% in 2022. It's down 57% so far in 2026.