LLY

Eli Lilly and Company

78
Fundamentals85/ 100
Valuation62/ 100
Upside potential72/ 100
Risk potential15/ 100

LLY has the edge over SOPH overall, supported by stronger fundamentals and lower modeled downside.

SOPH

SOPHiA GENETICS S.A.

60
Fundamentals63/ 100
Valuation50/ 100
Upside potential59/ 100
Risk potential30/ 100

SOPH's outlook is improving, though it still trails on the overall score.

LLY Fundamentals

MetricStatus
Healthy
Strong
Strong
Healthy

LLY's revenue, profitability, cash flow and balance sheet are all currently healthy.

SOPH Fundamentals

MetricStatus
Healthy
Under pressure
Weak
Unavailable

SOPH's revenue is currently healthy, but its profitability and cash flow are under pressure. There isn't enough data to rate its balance sheet.

LLY PE Valuation

CHEAPFAIREXPENSIVE37x74x111x147x
CHEAPFAIREXPENSIVE37x74x111x147x
LevelPEPriceVs current
Cheap27x$845-41%
Forward30x$1,427—
Current46x$1,427—
Fair48x$1,466+2.7%
Expensive85x$2,612+83%

Historical ranges are pointers, not guarantees.

LLY's PE is in its fair range at 46x. If earnings grow as analysts expect, today's price would be 30x next year's earnings, in its cheap range.

SOPH PE Valuation

SOPH has no meaningful PE right now: it lost money over the past year.

LLY Forward outlook

MetricOutlook
Strongly improving
Strong growth
Strong growth
Strongly improving
Limited
Moderate

Analysts expect strong earnings and revenue growth for LLY, with profitability improving.

SOPH Forward outlook

MetricOutlook
--
Losses shrinking
Strong growth
Strongly improving
Limited
High

Analysts expect SOPH's losses to shrink, with revenue growing.

LLY Risk to reward

ScenarioChangePrice
Upside+39%$1,988.49
Downside-15%$1,209.08

Calculated from the latest close: $1,427.28 on Nov 12.

LLY has a better modeled risk to reward balance than SOPH, with more potential upside relative to its potential downside.

SOPH Risk to reward

ScenarioChangePrice
Upside+45%$11.37
Downside-30%$5.47

Calculated from the latest close: $7.86 on Nov 12.

SOPH trails LLY on modeled risk to reward, with less potential upside relative to its potential downside.

LLY Earnings Per Share

Q4 2023: $5.80Q1 2024: $6.79Q2 2024: $8.12Q3 2024: $9.25Q4 2024: $11.71Q1 2025: $12.29Q2 2025: $15.30Q3 2025: $20.44Q4 2025: $22.95Q1 2026: $28.15Q2 2026: $29.80Q3 2026: $30.81Forward: $46.82
Q4 2023: $5.80Q1 2024: $6.79Q2 2024: $8.12Q3 2024: $9.25Q4 2024: $11.71Q1 2025: $12.29Q2 2025: $15.30Q3 2025: $20.44Q4 2025: $22.95Q1 2026: $28.15Q2 2026: $29.80Q3 2026: $30.81Forward: $46.82
QuarterTTM EPSYoY
Forward$46.82+52%
Q3 2026$30.81+51%
Q2 2026$29.80+95%
Q1 2026$28.15+129%
Q4 2025$22.95+96%
Q3 2025$20.44+121%
Q2 2025$15.30+88%
Q1 2025$12.29+81%
Q4 2024$11.71+102%

LLY has the edge over SOPH on earnings quality, reporting a profit while its opponent remains loss making.

SOPH Earnings Per Share

Q3 2023: $-1.07Q4 2023: $-1.22Q1 2024: $-1.12Q2 2024: $-1.02Q3 2024: $-1.09Q4 2024: $-0.95Q1 2025: $-1.00Q2 2025: $-1.10Q3 2025: $-1.12Q4 2025: $-1.17Q1 2026: $-1.18Q2 2026: $-1.15
Q3 2023: $-1.07Q4 2023: $-1.22Q1 2024: $-1.12Q2 2024: $-1.02Q3 2024: $-1.09Q4 2024: $-0.95Q1 2025: $-1.00Q2 2025: $-1.10Q3 2025: $-1.12Q4 2025: $-1.17Q1 2026: $-1.18Q2 2026: $-1.15
QuarterTTM EPSYoY
Q2 2026-$1.15-$0.05
Q1 2026-$1.18-$0.18
Q4 2025-$1.17-$0.22
Q3 2025-$1.12-$0.03
Q2 2025-$1.10-$0.08
Q1 2025-$1.00+$0.12
Q4 2024-$0.95+$0.27
Q3 2024-$1.09-$0.02

SOPH is still losing money, but less than at its worst: $1.15 per share over the past year, against $1.51 at its worst in late 2022.

LLY Quarterly Revenue

Q4 2023: $9.4BQ1 2024: $8.8BQ2 2024: $11.3BQ3 2024: $11.4BQ4 2024: $13.5BQ1 2025: $12.7BQ2 2025: $15.6BQ3 2025: $17.6BQ4 2025: $19.3BQ1 2026: $19.8BQ2 2026: $23BQ3 2026: $24.4B
Q4 2023: $9.4BQ1 2024: $8.8BQ2 2024: $11.3BQ3 2024: $11.4BQ4 2024: $13.5BQ1 2025: $12.7BQ2 2025: $15.6BQ3 2025: $17.6BQ4 2025: $19.3BQ1 2026: $19.8BQ2 2026: $23BQ3 2026: $24.4B
QuarterRevenueYoY
Q3 2026$24.4B+39%
Q2 2026$23B+48%
Q1 2026$19.8B+56%
Q4 2025$19.3B+43%
Q3 2025$17.6B+54%
Q2 2025$15.6B+38%
Q1 2025$12.7B+45%
Q4 2024$13.5B+45%

LLY has the edge over SOPH on sales, with more consistent year-over-year improvement.

SOPH Quarterly Revenue

Q3 2023: $16MQ4 2023: $17MQ1 2024: $16MQ2 2024: $16MQ3 2024: $16MQ4 2024: $18MQ1 2025: $18MQ2 2025: $18MQ3 2025: $19MQ4 2025: $22MQ1 2026: $22MQ2 2026: $23M
Q3 2023: $16MQ4 2023: $17MQ1 2024: $16MQ2 2024: $16MQ3 2024: $16MQ4 2024: $18MQ1 2025: $18MQ2 2025: $18MQ3 2025: $19MQ4 2025: $22MQ1 2026: $22MQ2 2026: $23M
QuarterRevenueYoY
Q2 2026$23.3M+27%
Q1 2026$21.7M+22%
Q4 2025$21.7M+22%
Q3 2025$19.5M+23%
Q2 2025$18.3M+16%
Q1 2025$17.8M+13%
Q4 2024$17.7M+4%
Q3 2024$15.9M-2.8%

SOPH's revenue has grown year over year for seven quarters in a row: $23M last quarter, up 27% from the same quarter a year ago.

LLY Free Cash Flow

Q4 2023: −$1.4BQ1 2024: $180MQ2 2024: $241MQ3 2024: $2.4BQ4 2024: $978MQ1 2025: $156MQ2 2025: $1.4BQ3 2025: $6.7BQ4 2025: $678MQ1 2026: $3BQ2 2026: $7.8BQ3 2026: $8.2B
Q4 2023: −$1.4BQ1 2024: $180MQ2 2024: $241MQ3 2024: $2.4BQ4 2024: $978MQ1 2025: $156MQ2 2025: $1.4BQ3 2025: $6.7BQ4 2025: $678MQ1 2026: $3BQ2 2026: $7.8BQ3 2026: $8.2B
QuarterFree cash flowYoY
Q3 2026$8.2B+22%
Q2 2026$7.8B+458%
Q1 2026$3B+1826%
Q4 2025$677.9M-31%
Q3 2025$6.7B+186%
Q2 2025$1.4B+476%
Q1 2025$156.1M-13%
Q4 2024$977.8M+$2.4B

LLY has the edge over SOPH on cash generation, producing positive trailing cash flow while its opponent burns cash.

SOPH Free Cash Flow

Q3 2023: −$14MQ4 2023: −$14MQ1 2024: −$17MQ2 2024: −$12MQ3 2024: −$9MQ4 2024: −$13MQ1 2025: −$12MQ2 2025: −$10MQ3 2025: −$9MQ4 2025: −$9MQ1 2026: −$17MQ2 2026: −$10M
Q3 2023: −$14MQ4 2023: −$14MQ1 2024: −$17MQ2 2024: −$12MQ3 2024: −$9MQ4 2024: −$13MQ1 2025: −$12MQ2 2025: −$10MQ3 2025: −$9MQ4 2025: −$9MQ1 2026: −$17MQ2 2026: −$10M
QuarterFree cash flowYoY
Q2 2026-$10.4M-$199K
Q1 2026-$17.1M-$4.8M
Q4 2025-$9.3M+$3.3M
Q3 2025-$8.9M+$581K
Q2 2025-$10.2M+$2.2M
Q1 2025-$12.2M+$4.4M
Q4 2024-$12.5M+$1M
Q3 2024-$9.5M+$4.8M

SOPH has burned cash in almost every quarter: −$46M over the past year, against −$44M the year before.

LLY Total Shares

Q4 2023: 903MQ1 2024: 904MQ2 2024: 904MQ3 2024: 905MQ4 2024: 904MQ1 2025: 901MQ2 2025: 900MQ3 2025: 899MQ4 2025: 899MQ1 2026: 896MQ2 2026: 894MQ3 2026: 893M
Q4 2023: 903MQ1 2024: 904MQ2 2024: 904MQ3 2024: 905MQ4 2024: 904MQ1 2025: 901MQ2 2025: 900MQ3 2025: 899MQ4 2025: 899MQ1 2026: 896MQ2 2026: 894MQ3 2026: 893M
PeriodChange %Net change
Quarterly0%-300K shares
1 year-0.6%-5.4M shares
3 years-0.7%-6.4M shares
5 years-1.9%-17.4M shares
Available history-4.5%-42.3M shares

LLY has the edge over SOPH on shareholder dilution, with a more favorable share count trend.

SOPH Total Shares

Q3 2023: 65MQ4 2023: 65MQ1 2024: 65MQ2 2024: 66MQ3 2024: 66MQ4 2024: 66MQ1 2025: 67MQ2 2025: 67MQ3 2025: 68MQ4 2025: 68MQ1 2026: 71MQ2 2026: 74M
Q3 2023: 65MQ4 2023: 65MQ1 2024: 65MQ2 2024: 66MQ3 2024: 66MQ4 2024: 66MQ1 2025: 67MQ2 2025: 67MQ3 2025: 68MQ4 2025: 68MQ1 2026: 71MQ2 2026: 74M
PeriodChange %Net change
Quarterly+3.8%+2.7M shares
1 year+9.7%+6.5M shares
3 years+14%+9.3M shares
5 years+17%+10.5M shares
Available history+92%+35.5M shares

SOPH has 74M diluted shares, up 9.7% from a year ago.

LLY Net Leverage

Q4 2023: 2.8xQ1 2024: 2.6xQ2 2024: 2.4xQ3 2024: 2.4xQ4 2024: 2.1xQ1 2025: 2.3xQ2 2025: 2.0xQ3 2025: 1.3xQ4 2025: 1.3xQ1 2026: 1.2xQ2 2026: 1.3xQ3 2026: 1.2x
Q4 2023: 2.8xQ1 2024: 2.6xQ2 2024: 2.4xQ3 2024: 2.4xQ4 2024: 2.1xQ1 2025: 2.3xQ2 2025: 2.0xQ3 2025: 1.3xQ4 2025: 1.3xQ1 2026: 1.2xQ2 2026: 1.3xQ3 2026: 1.2x
QuarterNet LeverageStatus
Q3 20261.2xHealthy
Q2 20261.3xHealthy
Q1 20261.2xHealthy
Q4 20251.3xHealthy
Q3 20251.3xHealthy
Q2 20252.0xHealthy
Q1 20252.3xModerate
Q4 20242.1xModerate

LLY's net debt is about 1.2 years of its operating earnings (EBITDA), about the same as a year ago.

SOPH Net Leverage

SOPH's operating earnings (EBITDA) were negative over the past year, so its debt can't be measured against them.

LLY Weekly Momentum

MetricValueStatus
RSI68.3Neutral
Stochastic84.1Overbought

LLY's weekly RSI is 68 (neutral) and its Stochastic is 84 (overbought).

SOPH Weekly Momentum

MetricValueStatus
RSI58.8Neutral
Stochastic56.5Neutral

SOPH's weekly RSI is 59 (neutral) and its Stochastic is 57 (neutral).

LLY PE vs Healthcare Sector

MetricLLYSector medianRelative
PE46x26x79% above
PE %482919 pts above

LLY is trading at 46x earnings, a 79% premium to the Healthcare sector's median of 26x.

SOPH PE vs Healthcare Sector

SOPH has no meaningful PE right now: it lost money over the past year.

LLY Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$1,279.412% above
20 week MA$1,218.817% above
50 week MA$1,102.229% above
100 week MA$954.150% above
200 week MA$797.579% above

LLY is in an uptrend: it's above all five of its weekly moving averages, and 79% above its 200-week average.

SOPH Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$7.573.8% above
20 week MA$7.258.4% above
50 week MA$5.8734% above
100 week MA$4.6868% above
200 week MA$4.3581% above

SOPH is in an uptrend: it's above all five of its weekly moving averages, and 81% above its 200-week average.

LLY Yearly ROI

YearStart priceEnd priceROI
2020$131.5$166.7+27%
2021$166.7$273.1+64%
2022$273.1$367.9+35%
2023$367.9$582.9+58%
2024$582.9$783.2+34%
2025$783.2$1,077.8+38%
2026 YTD$1,077.8$1,427.3+32%

LLY has finished every year since 2020 higher, and it's up 32% so far in 2026.

SOPH Yearly ROI

YearStart priceEnd priceROI
2021$16.8$13.7-19%
2022$13.7$2.85-79%
2023$2.85$4.71+65%
2024$4.71$3.36-29%
2025$3.36$4.73+41%
2026 YTD$4.73$7.86+66%

SOPH has the edge over LLY on returns for 2026, with the stronger performance.

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