LLY

Eli Lilly and Company

78
Fundamentals85/ 100
Valuation62/ 100
Upside potential72/ 100
Risk potential15/ 100

LLY's fundamentals are strong: revenue grew 46% and it turned 23% of its revenue into free cash flow. At 46x earnings, it's trading in line with its usual 48x. Analysts expect that strong growth to continue.

SION

Sionna Therapeutics, Inc.

There isn't enough reported data to score SION yet.

LLY Fundamentals

MetricStatus
Healthy
Strong
Strong
Healthy

LLY's revenue, profitability, cash flow and balance sheet are all currently healthy.

SION Fundamentals

MetricStatus
Unavailable
Weak
Unavailable
Unavailable

SION's profitability is currently weak. There isn't enough data to rate its revenue, cash flow and balance sheet.

LLY PE Valuation

CHEAPFAIREXPENSIVE37x74x111x147x
CHEAPFAIREXPENSIVE37x74x111x147x
LevelPEPriceVs current
Cheap27x$845-41%
Forward30x$1,427—
Current46x$1,427—
Fair48x$1,466+2.7%
Expensive85x$2,612+83%

Historical ranges are pointers, not guarantees.

LLY's PE is in its fair range at 46x. If earnings grow as analysts expect, today's price would be 30x next year's earnings, in its cheap range.

SION PE Valuation

SION has no meaningful PE right now: it lost money over the past year.

LLY Forward outlook

MetricOutlook
Strongly improving
Strong growth
Strong growth
Strongly improving
Limited
Moderate

Analysts expect strong earnings and revenue growth for LLY, with profitability improving.

SION Forward outlook

MetricOutlook
--
Losses shrinking
--
--
Limited
Low

Analysts expect SION's losses to shrink, with revenue holding steady. However, they disagree widely on these estimates.

LLY Risk to reward

ScenarioChangePrice
Upside+39%$1,988.49
Downside-15%$1,209.08

Calculated from the latest close: $1,427.28 on Nov 12.

There is not enough scenario data to compare LLY and SION's risk to reward.

SION Risk to reward

ScenarioChangePrice
UpsideUnknown—
DownsideUnknown—

Calculated from the latest close: $3.43 on Nov 12.

There is not enough scenario data to compare LLY and SION's risk to reward.

LLY Earnings Per Share

Q4 2023: $5.80Q1 2024: $6.79Q2 2024: $8.12Q3 2024: $9.25Q4 2024: $11.71Q1 2025: $12.29Q2 2025: $15.30Q3 2025: $20.44Q4 2025: $22.95Q1 2026: $28.15Q2 2026: $29.80Q3 2026: $30.81Forward: $46.82
Q4 2023: $5.80Q1 2024: $6.79Q2 2024: $8.12Q3 2024: $9.25Q4 2024: $11.71Q1 2025: $12.29Q2 2025: $15.30Q3 2025: $20.44Q4 2025: $22.95Q1 2026: $28.15Q2 2026: $29.80Q3 2026: $30.81Forward: $46.82
QuarterTTM EPSYoY
Forward$46.82+52%
Q3 2026$30.81+51%
Q2 2026$29.80+95%
Q1 2026$28.15+129%
Q4 2025$22.95+96%
Q3 2025$20.44+121%
Q2 2025$15.30+88%
Q1 2025$12.29+81%
Q4 2024$11.71+102%

LLY's earnings per share have climbed steadily: $30.81 over the past year, up 51% from the year before, and higher year over year for 11 quarters in a row.

SION Earnings Per Share

Q3 2024: $-1.31Q4 2024: $-1.40Q2 2026: $-2.18Q3 2026: $-2.44
Q3 2024: $-1.31Q4 2024: $-1.40Q2 2026: $-2.18Q3 2026: $-2.44

SION and LLY do not have enough comparable growth data to identify a winner.

LLY Quarterly Revenue

Q4 2023: $9.4BQ1 2024: $8.8BQ2 2024: $11.3BQ3 2024: $11.4BQ4 2024: $13.5BQ1 2025: $12.7BQ2 2025: $15.6BQ3 2025: $17.6BQ4 2025: $19.3BQ1 2026: $19.8BQ2 2026: $23BQ3 2026: $24.4B
Q4 2023: $9.4BQ1 2024: $8.8BQ2 2024: $11.3BQ3 2024: $11.4BQ4 2024: $13.5BQ1 2025: $12.7BQ2 2025: $15.6BQ3 2025: $17.6BQ4 2025: $19.3BQ1 2026: $19.8BQ2 2026: $23BQ3 2026: $24.4B
QuarterRevenueYoY
Q3 2026$24.4B+39%
Q2 2026$23B+48%
Q1 2026$19.8B+56%
Q4 2025$19.3B+43%
Q3 2025$17.6B+54%
Q2 2025$15.6B+38%
Q1 2025$12.7B+45%
Q4 2024$13.5B+45%

LLY's revenue has grown year over year for 14 quarters in a row: $24.4B last quarter, up 39% from the same quarter a year ago.

SION Quarterly Revenue

Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: --Q2 2025: --Q3 2025: --Q4 2025: --Q1 2026: --Q2 2026: --Q3 2026: --
Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: --Q2 2025: --Q3 2025: --Q4 2025: --Q1 2026: --Q2 2026: --Q3 2026: --

SION and LLY do not have enough comparable growth data to identify a winner.

LLY Free Cash Flow

Q4 2023: −$1.4BQ1 2024: $180MQ2 2024: $241MQ3 2024: $2.4BQ4 2024: $978MQ1 2025: $156MQ2 2025: $1.4BQ3 2025: $6.7BQ4 2025: $678MQ1 2026: $3BQ2 2026: $7.8BQ3 2026: $8.2B
Q4 2023: −$1.4BQ1 2024: $180MQ2 2024: $241MQ3 2024: $2.4BQ4 2024: $978MQ1 2025: $156MQ2 2025: $1.4BQ3 2025: $6.7BQ4 2025: $678MQ1 2026: $3BQ2 2026: $7.8BQ3 2026: $8.2B
QuarterFree cash flowYoY
Q3 2026$8.2B+22%
Q2 2026$7.8B+458%
Q1 2026$3B+1826%
Q4 2025$677.9M-31%
Q3 2025$6.7B+186%
Q2 2025$1.4B+476%
Q1 2025$156.1M-13%
Q4 2024$977.8M+$2.4B

LLY has the edge over SION on cash generation, producing positive trailing cash flow while its opponent burns cash.

SION Free Cash Flow

Q4 2023: −$8MQ1 2024: −$13MQ2 2024: −$10MQ3 2024: −$18MQ4 2024: −$12MQ1 2025: −$16MQ2 2025: −$18MQ3 2025: −$15MQ4 2025: −$17MQ1 2026: −$22MQ2 2026: −$22MQ3 2026: −$19M
Q4 2023: −$8MQ1 2024: −$13MQ2 2024: −$10MQ3 2024: −$18MQ4 2024: −$12MQ1 2025: −$16MQ2 2025: −$18MQ3 2025: −$15MQ4 2025: −$17MQ1 2026: −$22MQ2 2026: −$22MQ3 2026: −$19M
QuarterFree cash flowYoY
Q3 2026-$18.7M-$3.4M
Q2 2026-$22.2M-$4.1M
Q1 2026-$21.8M-$5.5M
Q4 2025-$16.8M-$5M
Q3 2025-$15.3M+$2.4M
Q2 2025-$18.2M-$8M
Q1 2025-$16.4M-$3.2M
Q4 2024-$11.8M-$4.2M

SION has burned cash in almost every quarter: −$80M over the past year, against −$62M the year before.

LLY Total Shares

Q4 2023: 903MQ1 2024: 904MQ2 2024: 904MQ3 2024: 905MQ4 2024: 904MQ1 2025: 901MQ2 2025: 900MQ3 2025: 899MQ4 2025: 899MQ1 2026: 896MQ2 2026: 894MQ3 2026: 893M
Q4 2023: 903MQ1 2024: 904MQ2 2024: 904MQ3 2024: 905MQ4 2024: 904MQ1 2025: 901MQ2 2025: 900MQ3 2025: 899MQ4 2025: 899MQ1 2026: 896MQ2 2026: 894MQ3 2026: 893M
PeriodChange %Net change
Quarterly0%-300K shares
1 year-0.6%-5.4M shares
3 years-0.7%-6.4M shares
5 years-1.9%-17.4M shares
Available history-4.5%-42.3M shares

LLY has the edge over SION on shareholder dilution, with a more favorable share count trend.

SION Total Shares

Q4 2023: 44MQ1 2024: 44MQ2 2024: 44MQ3 2024: 44MQ4 2024: 44MQ1 2025: 27MQ2 2025: 44MQ3 2025: 44MQ4 2025: 40MQ1 2026: 45MQ2 2026: 45MQ3 2026: 45M
Q4 2023: 44MQ1 2024: 44MQ2 2024: 44MQ3 2024: 44MQ4 2024: 44MQ1 2025: 27MQ2 2025: 44MQ3 2025: 44MQ4 2025: 40MQ1 2026: 45MQ2 2026: 45MQ3 2026: 45M
PeriodChange %Net change
Quarterly+0.1%+60K shares
1 year+2.2%+954K shares

SION has 45M diluted shares, up 2.2% from a year ago.

LLY Net Leverage

Q4 2023: 2.8xQ1 2024: 2.6xQ2 2024: 2.4xQ3 2024: 2.4xQ4 2024: 2.1xQ1 2025: 2.3xQ2 2025: 2.0xQ3 2025: 1.3xQ4 2025: 1.3xQ1 2026: 1.2xQ2 2026: 1.3xQ3 2026: 1.2x
Q4 2023: 2.8xQ1 2024: 2.6xQ2 2024: 2.4xQ3 2024: 2.4xQ4 2024: 2.1xQ1 2025: 2.3xQ2 2025: 2.0xQ3 2025: 1.3xQ4 2025: 1.3xQ1 2026: 1.2xQ2 2026: 1.3xQ3 2026: 1.2x
QuarterNet LeverageStatus
Q3 20261.2xHealthy
Q2 20261.3xHealthy
Q1 20261.2xHealthy
Q4 20251.3xHealthy
Q3 20251.3xHealthy
Q2 20252.0xHealthy
Q1 20252.3xModerate
Q4 20242.1xModerate

LLY's net debt is about 1.2 years of its operating earnings (EBITDA), about the same as a year ago.

SION Net Leverage

SION's operating earnings (EBITDA) were negative over the past year, so its debt can't be measured against them.

LLY Weekly Momentum

MetricValueStatus
RSI68.3Neutral
Stochastic84.1Overbought

LLY's weekly RSI is 68 (neutral) and its Stochastic is 84 (overbought).

SION Weekly Momentum

MetricValueStatus
RSI28.5Oversold
Stochastic1.8Oversold

SION's weekly RSI is 29 (oversold) and its Stochastic is 2 (oversold).

LLY PE vs Healthcare Sector

MetricLLYSector medianRelative
PE46x26x79% above
PE %482919 pts above

LLY is trading at 46x earnings, a 79% premium to the Healthcare sector's median of 26x.

SION PE vs Healthcare Sector

SION has no meaningful PE right now: it lost money over the past year.

LLY Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$1,279.412% above
20 week MA$1,218.817% above
50 week MA$1,102.229% above
100 week MA$954.150% above
200 week MA$797.579% above

LLY has stronger trend alignment. LLY is above 5 of 5 weekly averages versus SION above 0 of 3.

SION Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$4.1417% below
20 week MA$17.781% below
50 week MA$30.789% below

SION is in a downtrend: it's below all three of its weekly moving averages, and 89% below its 50-week average.

LLY Yearly ROI

YearStart priceEnd priceROI
2020$131.5$166.7+27%
2021$166.7$273.1+64%
2022$273.1$367.9+35%
2023$367.9$582.9+58%
2024$582.9$783.2+34%
2025$783.2$1,077.8+38%
2026 YTD$1,077.8$1,427.3+32%

LLY has the edge over SION on returns for 2026, with the stronger performance.

SION Yearly ROI

YearStart priceEnd priceROI
2025$25.0$43.7+75%
2026 YTD$43.7$3.43-92%

SION has finished every year since 2025 higher, and it's down 92% so far in 2026.

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