LLY

Eli Lilly and Company

78
Fundamentals85/ 100
Valuation62/ 100
Upside potential72/ 100
Risk potential15/ 100

LLY's fundamentals are strong: revenue grew 46% and it turned 23% of its revenue into free cash flow. At 46x earnings, it's trading in line with its usual 48x. Analysts expect that strong growth to continue.

PRTA

Prothena Corporation plc

There isn't enough reported data to score PRTA yet.

LLY Fundamentals

MetricStatus
Healthy
Strong
Strong
Healthy

LLY's revenue, profitability, cash flow and balance sheet are all currently healthy.

PRTA Fundamentals

MetricStatus
Healthy
Under pressure
Under pressure
Strong

PRTA's revenue and balance sheet are currently healthy, but its profitability and cash flow are under pressure.

LLY PE Valuation

CHEAPFAIREXPENSIVE37x74x111x147x
CHEAPFAIREXPENSIVE37x74x111x147x
LevelPEPriceVs current
Cheap27x$845-41%
Forward30x$1,427โ€”
Current46x$1,427โ€”
Fair48x$1,466+2.7%
Expensive85x$2,612+83%

Historical ranges are pointers, not guarantees.

LLY's PE is in its fair range at 46x. If earnings grow as analysts expect, today's price would be 30x next year's earnings, in its cheap range.

PRTA PE Valuation

PRTA has no meaningful PE right now: it lost money over the past year.

LLY Forward outlook

MetricOutlook
Strongly improving
Strong growth
Strong growth
Strongly improving
Limited
Moderate

Analysts expect strong earnings and revenue growth for LLY, with profitability improving.

PRTA Forward outlook

MetricOutlook
--
Losses shrinking
Strong growth
--
Limited
Low

Analysts expect PRTA's losses to shrink, with revenue growing. However, they disagree widely on these estimates.

LLY Risk to reward

ScenarioChangePrice
Upside+39%$1,988.49
Downside-15%$1,209.08

Calculated from the latest close: $1,427.28 on Nov 12.

There is not enough scenario data to compare LLY and PRTA's risk to reward.

PRTA Risk to reward

ScenarioChangePrice
UpsideUnknownโ€”
DownsideUnknownโ€”

Calculated from the latest close: $8.23 on Nov 12.

There is not enough scenario data to compare LLY and PRTA's risk to reward.

LLY Earnings Per Share

Q4 2023: $5.80Q1 2024: $6.79Q2 2024: $8.12Q3 2024: $9.25Q4 2024: $11.71Q1 2025: $12.29Q2 2025: $15.30Q3 2025: $20.44Q4 2025: $22.95Q1 2026: $28.15Q2 2026: $29.80Q3 2026: $30.81Forward: $46.82
Q4 2023: $5.80Q1 2024: $6.79Q2 2024: $8.12Q3 2024: $9.25Q4 2024: $11.71Q1 2025: $12.29Q2 2025: $15.30Q3 2025: $20.44Q4 2025: $22.95Q1 2026: $28.15Q2 2026: $29.80Q3 2026: $30.81Forward: $46.82
QuarterTTM EPSYoY
Forward$46.82+52%
Q3 2026$30.81+51%
Q2 2026$29.80+95%
Q1 2026$28.15+129%
Q4 2025$22.95+96%
Q3 2025$20.44+121%
Q2 2025$15.30+88%
Q1 2025$12.29+81%
Q4 2024$11.71+102%

LLY has the edge over PRTA on earnings quality, reporting a profit while its opponent remains loss making.

PRTA Earnings Per Share

Q4 2023: $-2.76Q1 2024: $-3.21Q2 2024: $-0.96Q3 2024: $-2.44Q4 2024: $-2.27Q1 2025: $-2.05Q2 2025: $-5.61Q3 2025: $-5.19Q4 2025: $-4.53Q1 2026: $-2.81Q2 2026: $-0.83Q3 2026: $-0.47
Q4 2023: $-2.76Q1 2024: $-3.21Q2 2024: $-0.96Q3 2024: $-2.44Q4 2024: $-2.27Q1 2025: $-2.05Q2 2025: $-5.61Q3 2025: $-5.19Q4 2025: $-4.53Q1 2026: $-2.81Q2 2026: $-0.83Q3 2026: $-0.47
QuarterTTM EPSYoY
Q3 2026-$0.47+$4.72
Q2 2026-$0.83+$4.78
Q1 2026-$2.81-$0.76
Q4 2025-$4.53-$2.26
Q3 2025-$5.19-$2.75
Q2 2025-$5.61-$4.65
Q1 2025-$2.05+$1.16
Q4 2024-$2.27+$0.49

PRTA is still losing money, but far less than before: $0.47 per share over the past year, against $5.61 at its worst in mid-2025.

LLY Quarterly Revenue

Q4 2023: $9.4BQ1 2024: $8.8BQ2 2024: $11.3BQ3 2024: $11.4BQ4 2024: $13.5BQ1 2025: $12.7BQ2 2025: $15.6BQ3 2025: $17.6BQ4 2025: $19.3BQ1 2026: $19.8BQ2 2026: $23BQ3 2026: $24.4B
Q4 2023: $9.4BQ1 2024: $8.8BQ2 2024: $11.3BQ3 2024: $11.4BQ4 2024: $13.5BQ1 2025: $12.7BQ2 2025: $15.6BQ3 2025: $17.6BQ4 2025: $19.3BQ1 2026: $19.8BQ2 2026: $23BQ3 2026: $24.4B
QuarterRevenueYoY
Q3 2026$24.4B+39%
Q2 2026$23B+48%
Q1 2026$19.8B+56%
Q4 2025$19.3B+43%
Q3 2025$17.6B+54%
Q2 2025$15.6B+38%
Q1 2025$12.7B+45%
Q4 2024$13.5B+45%

LLY has the edge over PRTA on sales, with more consistent year-over-year improvement.

PRTA Quarterly Revenue

Q4 2023: $316,000Q1 2024: $50,000Q2 2024: $132MQ3 2024: $970,000Q4 2024: $2MQ1 2025: $3MQ2 2025: $4MQ3 2025: $2MQ4 2025: $21,000Q1 2026: $51MQ2 2026: $1MQ3 2026: $620,000
Q4 2023: $316,000Q1 2024: $50,000Q2 2024: $132MQ3 2024: $970,000Q4 2024: $2MQ1 2025: $3MQ2 2025: $4MQ3 2025: $2MQ4 2025: $21,000Q1 2026: $51MQ2 2026: $1MQ3 2026: $620,000
QuarterRevenueYoY
Q3 2026$620K-74%
Q2 2026$1M-77%
Q1 2026$51.1M+1706%
Q4 2025$21K-99%
Q3 2025$2.4M+149%
Q2 2025$4.4M-97%
Q1 2025$2.8M+5556%
Q4 2024$2.1M+572%

PRTA's revenue is growing: $620,000 last quarter, down 74% from the same quarter a year ago.

LLY Free Cash Flow

Q4 2023: โˆ’$1.4BQ1 2024: $180MQ2 2024: $241MQ3 2024: $2.4BQ4 2024: $978MQ1 2025: $156MQ2 2025: $1.4BQ3 2025: $6.7BQ4 2025: $678MQ1 2026: $3BQ2 2026: $7.8BQ3 2026: $8.2B
Q4 2023: โˆ’$1.4BQ1 2024: $180MQ2 2024: $241MQ3 2024: $2.4BQ4 2024: $978MQ1 2025: $156MQ2 2025: $1.4BQ3 2025: $6.7BQ4 2025: $678MQ1 2026: $3BQ2 2026: $7.8BQ3 2026: $8.2B
QuarterFree cash flowYoY
Q3 2026$8.2B+22%
Q2 2026$7.8B+458%
Q1 2026$3B+1826%
Q4 2025$677.9M-31%
Q3 2025$6.7B+186%
Q2 2025$1.4B+476%
Q1 2025$156.1M-13%
Q4 2024$977.8M+$2.4B

LLY has the edge over PRTA on cash generation, producing positive trailing cash flow while its opponent burns cash.

PRTA Free Cash Flow

Q4 2023: โˆ’$51MQ1 2024: โˆ’$73MQ2 2024: $16MQ3 2024: โˆ’$45MQ4 2024: โˆ’$48MQ1 2025: โˆ’$53MQ2 2025: โˆ’$46MQ3 2025: โˆ’$41MQ4 2025: โˆ’$23MQ1 2026: $29MQ2 2026: โˆ’$25MQ3 2026: โˆ’$12M
Q4 2023: โˆ’$51MQ1 2024: โˆ’$73MQ2 2024: $16MQ3 2024: โˆ’$45MQ4 2024: โˆ’$48MQ1 2025: โˆ’$53MQ2 2025: โˆ’$46MQ3 2025: โˆ’$41MQ4 2025: โˆ’$23MQ1 2026: $29MQ2 2026: โˆ’$25MQ3 2026: โˆ’$12M
QuarterFree cash flowYoY
Q3 2026-$12M+$28.6M
Q2 2026-$25M+$21.3M
Q1 2026$28.9M+$82.2M
Q4 2025-$23.3M+$24.5M
Q3 2025-$40.6M+$4.6M
Q2 2025-$46.3M-390%
Q1 2025-$53.4M+$19.7M
Q4 2024-$47.8M+$3.3M

PRTA has burned cash in most quarters: โˆ’$31M over the past year, against โˆ’$188M the year before.

LLY Total Shares

Q4 2023: 903MQ1 2024: 904MQ2 2024: 904MQ3 2024: 905MQ4 2024: 904MQ1 2025: 901MQ2 2025: 900MQ3 2025: 899MQ4 2025: 899MQ1 2026: 896MQ2 2026: 894MQ3 2026: 893M
Q4 2023: 903MQ1 2024: 904MQ2 2024: 904MQ3 2024: 905MQ4 2024: 904MQ1 2025: 901MQ2 2025: 900MQ3 2025: 899MQ4 2025: 899MQ1 2026: 896MQ2 2026: 894MQ3 2026: 893M
PeriodChange %Net change
Quarterly0%-300K shares
1 year-0.6%-5.4M shares
3 years-0.7%-6.4M shares
5 years-1.9%-17.4M shares
Available history-4.5%-42.3M shares

LLY has 893M diluted shares, down 0.6% from a year ago.

PRTA Total Shares

Q4 2023: 53MQ1 2024: 54MQ2 2024: 55MQ3 2024: 54MQ4 2024: 54MQ1 2025: 54MQ2 2025: 54MQ3 2025: 54MQ4 2025: 54MQ1 2026: 54MQ2 2026: 52MQ3 2026: 51M
Q4 2023: 53MQ1 2024: 54MQ2 2024: 55MQ3 2024: 54MQ4 2024: 54MQ1 2025: 54MQ2 2025: 54MQ3 2025: 54MQ4 2025: 54MQ1 2026: 54MQ2 2026: 52MQ3 2026: 51M
PeriodChange %Net change
Quarterly-1.4%-708K shares
1 year-4.4%-2.4M shares
3 years-11%-6.6M shares
5 years+0.5%+232K shares
Available history+29%+11.6M shares

PRTA has the edge over LLY on shareholder dilution, with a more favorable share count trend.

LLY Net Leverage

Q4 2023: 2.8xQ1 2024: 2.6xQ2 2024: 2.4xQ3 2024: 2.4xQ4 2024: 2.1xQ1 2025: 2.3xQ2 2025: 2.0xQ3 2025: 1.3xQ4 2025: 1.3xQ1 2026: 1.2xQ2 2026: 1.3xQ3 2026: 1.2x
Q4 2023: 2.8xQ1 2024: 2.6xQ2 2024: 2.4xQ3 2024: 2.4xQ4 2024: 2.1xQ1 2025: 2.3xQ2 2025: 2.0xQ3 2025: 1.3xQ4 2025: 1.3xQ1 2026: 1.2xQ2 2026: 1.3xQ3 2026: 1.2x
QuarterNet LeverageStatus
Q3 20261.2xHealthy
Q2 20261.3xHealthy
Q1 20261.2xHealthy
Q4 20251.3xHealthy
Q3 20251.3xHealthy
Q2 20252.0xHealthy
Q1 20252.3xModerate
Q4 20242.1xModerate

LLY's net debt is about 1.2 years of its operating earnings (EBITDA), about the same as a year ago.

PRTA Net Leverage

QuarterNet LeverageStatus
Q1 2022-8.1xNet Cash
Q4 2021-7.9xNet Cash
Q3 2021-7.9xNet Cash

PRTA has more cash than debt.

LLY Weekly Momentum

MetricValueStatus
RSI68.3Neutral
Stochastic84.1Overbought

LLY's weekly RSI is 68 (neutral) and its Stochastic is 84 (overbought).

PRTA Weekly Momentum

MetricValueStatus
RSI44.3Neutral
Stochastic20.5Neutral

PRTA's weekly RSI is 44 (neutral) and its Stochastic is 21 (neutral).

LLY PE vs Healthcare Sector

MetricLLYSector medianRelative
PE46x26x79% above
PE %482919 pts above

LLY is trading at 46x earnings, a 79% premium to the Healthcare sector's median of 26x.

PRTA PE vs Healthcare Sector

MetricPRTASector medianRelative
PEN/A26xโ€”

PRTA has no meaningful PE right now: it lost money over the past year.

LLY Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$1,279.412% above
20 week MA$1,218.817% above
50 week MA$1,102.229% above
100 week MA$954.150% above
200 week MA$797.579% above

LLY has the edge over PRTA on trend strength, trading above more of its moving averages.

PRTA Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$8.341.3% below
20 week MA$8.745.8% below
50 week MA$9.2611% below
100 week MA$9.6715% below
200 week MA$23.865% below

PRTA is in a downtrend: it's below all five of its weekly moving averages, and 65% below its 200-week average.

LLY Yearly ROI

YearStart priceEnd priceROI
2020$131.5$166.7+27%
2021$166.7$273.1+64%
2022$273.1$367.9+35%
2023$367.9$582.9+58%
2024$582.9$783.2+34%
2025$783.2$1,077.8+38%
2026 YTD$1,077.8$1,427.3+32%

LLY has the edge over PRTA on returns for 2026, with the stronger performance.

PRTA Yearly ROI

YearStart priceEnd priceROI
2020$16.0$13.2-17%
2021$13.2$48.4+265%
2022$48.4$57.8+19%
2023$57.8$36.3-37%
2024$36.3$15.1-58%
2025$15.1$9.54-37%
2026 YTD$9.54$8.23-14%

PRTA has finished three years in a row lower, and it's down 14% so far in 2026.

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