LGND

Ligand Pharmaceuticals Incorporated

55
Fundamentals68/ 100
Valuation28/ 100
Upside potential6/ 100
Risk potential79/ 100

LGND offers stronger fundamentals, but that advantage does not outweigh its weaker overall profile.

UNH

UnitedHealth Group Incorporated

62
Fundamentals51/ 100
Valuation56/ 100
Upside potential71/ 100
Risk potential15/ 100

UNH has the edge over LGND overall, supported by stronger modeled upside and lower modeled downside.

LGND Fundamentals

MetricStatus
Under pressure
Stable
Strong
Weak

LGND's cash flow is currently strong, and its profitability is stable, but its revenue and balance sheet are under pressure.

UNH Fundamentals

MetricStatus
Stable
Stable
Healthy
Healthy

UNH's cash flow and balance sheet are currently healthy, and its revenue and profitability are stable.

LGND PE Valuation

CHEAPFAIREXPENSIVE33x66x99x132x
CHEAPFAIREXPENSIVE33x66x99x132x
LevelPEPriceVs current
Cheap25x$62.36-80%
Forward29x$316—
Fair42x$106-67%
Expensive67x$170-46%
Current125x$316—

Historical ranges are pointers, not guarantees.

LGND's PE is in its expensive range at 125x, but its recent earnings include one-off gains. If earnings grow as analysts expect, today's price would be 29x next year's earnings, in its cheap range.

UNH PE Valuation

CHEAPFAIREXPENSIVE10x21x31x42x
CHEAPFAIREXPENSIVE10x21x31x42x
LevelPEPriceVs current
Forward18x$405—
Cheap19x$325-20%
Fair23x$410+1.2%
Current23x$405—
Expensive30x$526+30%

Historical ranges are pointers, not guarantees.

UNH has the edge over LGND in the historical PE scenario, which offers more potential upside but is not a forecast.

LGND Forward outlook

MetricOutlook
Strongly improving
Strong growth
Strong growth
Improving
Limited
Moderate

LGND has the edge over UNH on the outlook, with more favorable revenue expectations.

UNH Forward outlook

MetricOutlook
Strongly improving
Strong growth
Stable
Improving
Moderate
Low

Analysts expect UNH's earnings to grow and its profitability to improve, with its revenue holding steady. However, they disagree widely on these estimates.

LGND Risk to reward

ScenarioChangePrice
Upside+5%$332.40
Downside-79%$65.30

Calculated from the latest close: $316.27 on Nov 12.

LGND trails UNH on modeled risk to reward, with less potential upside and more potential downside.

UNH Risk to reward

ScenarioChangePrice
Upside+36%$550.65
Downside-15%$346.07

Calculated from the latest close: $405.13 on Nov 12.

UNH has a better modeled risk to reward balance than LGND, with more potential upside and less potential downside.

LGND Earnings Per Share

Q4 2023: $2.94Q1 2024: $5.36Q2 2024: $2.35Q3 2024: $2.55Q4 2024: $-0.22Q1 2025: $-7.18Q2 2025: $-4.06Q3 2025: $2.01Q4 2025: $6.13Q1 2026: $7.67Q2 2026: $9.65Q3 2026: $2.54Forward: $10.93
Q4 2023: $2.94Q1 2024: $5.36Q2 2024: $2.35Q3 2024: $2.55Q4 2024: $-0.22Q1 2025: $-7.18Q2 2025: $-4.06Q3 2025: $2.01Q4 2025: $6.13Q1 2026: $7.67Q2 2026: $9.65Q3 2026: $2.54Forward: $10.93
QuarterTTM EPSYoY
Forward$10.93+330%
Q3 2026$2.54+26%
Q2 2026$9.65+$13.71
Q1 2026$7.67+$14.85
Q4 2025$6.13+$6.35
Q3 2025$2.01-21%
Q2 2025-$4.06-273%
Q1 2025-$7.18-234%
Q4 2024-$0.22-107%

LGND has the edge over UNH on earnings, with more consistent year-over-year improvement.

UNH Earnings Per Share

Q4 2023: $23.86Q1 2024: $16.38Q2 2024: $15.10Q3 2024: $15.37Q4 2024: $15.51Q1 2025: $23.89Q2 2025: $23.09Q3 2025: $19.17Q4 2025: $13.23Q1 2026: $13.28Q2 2026: $15.58Q3 2026: $17.55Forward: $22.65
Q4 2023: $23.86Q1 2024: $16.38Q2 2024: $15.10Q3 2024: $15.37Q4 2024: $15.51Q1 2025: $23.89Q2 2025: $23.09Q3 2025: $19.17Q4 2025: $13.23Q1 2026: $13.28Q2 2026: $15.58Q3 2026: $17.55Forward: $22.65
QuarterTTM EPSYoY
Forward$22.65+29%
Q3 2026$17.55-8.5%
Q2 2026$15.58-33%
Q1 2026$13.28-44%
Q4 2025$13.23-15%
Q3 2025$19.17+25%
Q2 2025$23.09+53%
Q1 2025$23.89+46%
Q4 2024$15.51-35%

UNH's earnings per share have fallen from their peak: $17.55 over the past year, against $23.89 in early 2025.

LGND Quarterly Revenue

Q4 2023: $28MQ1 2024: $31MQ2 2024: $42MQ3 2024: $52MQ4 2024: $43MQ1 2025: $45MQ2 2025: $48MQ3 2025: $115MQ4 2025: $60MQ1 2026: $52MQ2 2026: $64MQ3 2026: $79M
Q4 2023: $28MQ1 2024: $31MQ2 2024: $42MQ3 2024: $52MQ4 2024: $43MQ1 2025: $45MQ2 2025: $48MQ3 2025: $115MQ4 2025: $60MQ1 2026: $52MQ2 2026: $64MQ3 2026: $79M
QuarterRevenueYoY
Q3 2026$78.7M-32%
Q2 2026$63.7M+34%
Q1 2026$51.7M+14%
Q4 2025$59.7M+39%
Q3 2025$115.5M+123%
Q2 2025$47.6M+15%
Q1 2025$45.3M+46%
Q4 2024$42.8M+52%

LGND has the edge over UNH on sales, with stronger typical year-over-year growth.

UNH Quarterly Revenue

Q4 2023: $94.4BQ1 2024: $99.8BQ2 2024: $98.9BQ3 2024: $101BQ4 2024: $101BQ1 2025: $110BQ2 2025: $112BQ3 2025: $113BQ4 2025: $113BQ1 2026: $112BQ2 2026: $112BQ3 2026: $113B
Q4 2023: $94.4BQ1 2024: $99.8BQ2 2024: $98.9BQ3 2024: $101BQ4 2024: $101BQ1 2025: $110BQ2 2025: $112BQ3 2025: $113BQ4 2025: $113BQ1 2026: $112BQ2 2026: $112BQ3 2026: $113B
QuarterRevenueYoY
Q3 2026$112.7B-0.4%
Q2 2026$112B+0.4%
Q1 2026$111.7B+2%
Q4 2025$113.2B+12%
Q3 2025$113.2B+12%
Q2 2025$111.6B+13%
Q1 2025$109.6B+9.8%
Q4 2024$100.8B+6.8%

UNH's revenue has held roughly level: $113B last quarter, about level with the same quarter a year ago.

LGND Free Cash Flow

Q4 2023: $8MQ1 2024: $19MQ2 2024: $13MQ3 2024: $36MQ4 2024: $28MQ1 2025: −$26MQ2 2025: $16MQ3 2025: $13MQ4 2025: $46MQ1 2026: $48MQ2 2026: $24MQ3 2026: −$28M
Q4 2023: $8MQ1 2024: $19MQ2 2024: $13MQ3 2024: $36MQ4 2024: $28MQ1 2025: −$26MQ2 2025: $16MQ3 2025: $13MQ4 2025: $46MQ1 2026: $48MQ2 2026: $24MQ3 2026: −$28M
QuarterFree cash flowYoY
Q3 2026-$27.7M-312%
Q2 2026$24M+54%
Q1 2026$48.5M+$74.1M
Q4 2025$45.9M+65%
Q3 2025$13.1M-64%
Q2 2025$15.6M+21%
Q1 2025-$25.7M-238%
Q4 2024$27.8M+263%

LGND usually generates cash, though not every quarter: the latest was −$28M, but it generated $91M over the past year.

UNH Free Cash Flow

Q4 2023: −$6.2BQ1 2024: $401MQ2 2024: $5.9BQ3 2024: $13BQ4 2024: $1.5BQ1 2025: $4.6BQ2 2025: $6.3BQ3 2025: $5.1BQ4 2025: $160MQ1 2026: $8.1BQ2 2026: $10.3BQ3 2026: $4.3B
Q4 2023: −$6.2BQ1 2024: $401MQ2 2024: $5.9BQ3 2024: $13BQ4 2024: $1.5BQ1 2025: $4.6BQ2 2025: $6.3BQ3 2025: $5.1BQ4 2025: $160MQ1 2026: $8.1BQ2 2026: $10.3BQ3 2026: $4.3B
QuarterFree cash flowYoY
Q3 2026$4.3B-16%
Q2 2026$10.3B+63%
Q1 2026$8.1B+79%
Q4 2025$160M-89%
Q3 2025$5.1B-61%
Q2 2025$6.3B+6.9%
Q1 2025$4.6B+1037%
Q4 2024$1.5B+$7.6B

UNH still generates free cash flow, though less than at its 2022 peak: $22.8B over the past year.

LGND Total Shares

Q4 2023: 18MQ1 2024: 18MQ2 2024: 18MQ3 2024: 18MQ4 2024: 18MQ1 2025: 19MQ2 2025: 20MQ3 2025: 21MQ4 2025: 20MQ1 2026: 20MQ2 2026: 22MQ3 2026: 20M
Q4 2023: 18MQ1 2024: 18MQ2 2024: 18MQ3 2024: 18MQ4 2024: 18MQ1 2025: 19MQ2 2025: 20MQ3 2025: 21MQ4 2025: 20MQ1 2026: 20MQ2 2026: 22MQ3 2026: 20M
PeriodChange %Net change
Quarterly-8.6%-1.9M shares
1 year-3.2%-667K shares
3 years+15%+2.6M shares
5 years+16%+2.8M shares
Available history+16%+2.7M shares

LGND has the edge over UNH on shareholder dilution, with a more favorable share count trend.

UNH Total Shares

Q4 2023: 938MQ1 2024: 922MQ2 2024: 928MQ3 2024: 930MQ4 2024: 929MQ1 2025: 918MQ2 2025: 910MQ3 2025: 908MQ4 2025: 911MQ1 2026: 910MQ2 2026: 906MQ3 2026: 902M
Q4 2023: 938MQ1 2024: 922MQ2 2024: 928MQ3 2024: 930MQ4 2024: 929MQ1 2025: 918MQ2 2025: 910MQ3 2025: 908MQ4 2025: 911MQ1 2026: 910MQ2 2026: 906MQ3 2026: 902M
PeriodChange %Net change
Quarterly-0.4%-4M shares
1 year-0.7%-6M shares
3 years-3.6%-34M shares
5 years-5.5%-53M shares
Available history-6.6%-64M shares

UNH has 902M diluted shares, down 0.7% from a year ago, with $5B in buybacks over the past year.

LGND Net Leverage

Q4 2023: -0.5xQ1 2024: -1.4xQ2 2024: -1.0xQ3 2024: -3.3xQ4 2024: -5.7xQ2 2025: -104.6xQ3 2025: -2.7xQ4 2025: -2.3xQ1 2026: -0.9xQ2 2026: 0.9xQ3 2026: 18.2x
Q4 2023: -0.5xQ1 2024: -1.4xQ2 2024: -1.0xQ3 2024: -3.3xQ4 2024: -5.7xQ2 2025: -104.6xQ3 2025: -2.7xQ4 2025: -2.3xQ1 2026: -0.9xQ2 2026: 0.9xQ3 2026: 18.2x
QuarterNet LeverageStatus
Q3 202618.2xHigh
Q2 20260.9xVery low
Q1 2026-0.9xNet Cash
Q4 2025-2.3xNet Cash
Q3 2025-2.7xNet Cash
Q2 2025-104.6xNet Cash
Q4 2024-5.7xNet Cash
Q3 2024-3.3xNet Cash

LGND's net debt is about 18 years of its operating earnings (EBITDA), after holding more cash than debt a year ago.

UNH Net Leverage

Q4 2023: 1.0xQ1 2024: 1.3xQ2 2024: 1.4xQ3 2024: 1.3xQ4 2024: 1.4xQ1 2025: 1.3xQ2 2025: 1.5xQ3 2025: 1.7xQ4 2025: 2.3xQ1 2026: 2.2xQ2 2026: 1.7xQ3 2026: 1.7x
Q4 2023: 1.0xQ1 2024: 1.3xQ2 2024: 1.4xQ3 2024: 1.3xQ4 2024: 1.4xQ1 2025: 1.3xQ2 2025: 1.5xQ3 2025: 1.7xQ4 2025: 2.3xQ1 2026: 2.2xQ2 2026: 1.7xQ3 2026: 1.7x
QuarterNet LeverageStatus
Q3 20261.7xHealthy
Q2 20261.7xHealthy
Q1 20262.2xModerate
Q4 20252.3xModerate
Q3 20251.7xHealthy
Q2 20251.5xHealthy
Q1 20251.3xHealthy
Q4 20241.4xHealthy

UNH has the edge over LGND on leverage, with a lower net debt burden relative to earnings.

LGND Weekly Momentum

MetricValueStatus
RSI64.7Neutral
Stochastic80.9Overbought

LGND's weekly RSI is 65 (neutral) and its Stochastic is 81 (overbought).

UNH Weekly Momentum

MetricValueStatus
RSI56.4Neutral
Stochastic60.0Neutral

UNH's weekly RSI is 56 (neutral) and its Stochastic is 60 (neutral).

LGND PE vs Healthcare Sector

MetricLGNDSector medianRelative
PE125x26x382% above
PE %1002971 pts above

LGND is trading at 125x earnings, a 382% premium to the Healthcare sector's median of 26x, though its recent earnings include one-off gains.

UNH PE vs Healthcare Sector

MetricUNHSector medianRelative
PE23x26x11% below
PE %472918 pts above

UNH has the edge over LGND on valuation relative to its sector.

LGND Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$306.33.2% above
20 week MA$299.35.7% above
50 week MA$247.328% above
100 week MA$191.166% above
200 week MA$135.3134% above

LGND has the edge over UNH on trend strength, trading above more of its moving averages.

UNH Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$394.22.8% above
20 week MA$400.51.2% above
50 week MA$361.212% above
100 week MA$376.07.8% above
200 week MA$446.69.3% below

UNH has bounced recently, but its long-term trend is still down: it's above its 8-, 20-, 50- and 100-week averages, but 9.3% below its 200-week average.

LGND Yearly ROI

YearStart priceEnd priceROI
2020$66.7$66.2-0.8%
2021$66.2$100.6+52%
2022$100.6$67.3-33%
2023$67.3$71.4+6.1%
2024$71.4$109.2+53%
2025$109.2$195.8+79%
2026 YTD$195.8$316.3+62%

LGND has the edge over UNH on returns for 2026, with the stronger performance.

UNH Yearly ROI

YearStart priceEnd priceROI
2020$296.0$340.8+15%
2021$340.8$495.4+45%
2022$495.4$531.3+7.3%
2023$531.3$526.5-0.9%
2024$526.5$510.0-3.1%
2025$510.0$331.8-35%
2026 YTD$331.8$405.1+22%

UNH has finished three years in a row lower, and it's up 22% so far in 2026.

Give your agent the market.

Get API key