KRYS

Krystal Biotech, Inc.

75
Fundamentals86/ 100
Valuation57/ 100
Upside potential70/ 100
Risk potential17/ 100

KRYS's fundamentals are strong: revenue grew 26% and its operating margin rose 6 points to 48%. At 42x earnings, it's trading in line with its usual 44x. Analysts expect that strong growth to continue.

KRYS Fundamentals

MetricStatus
Healthy
Strong
Strong
Strong

KRYS's revenue, profitability, cash flow and balance sheet are all currently healthy.

KRYS PE Valuation

CHEAPFAIREXPENSIVE120x240x360x480x
CHEAPFAIREXPENSIVE120x240x360x480x
LevelPEPriceVs current
Cheap35x$261-15%
Forward35x$306—
Current42x$306—
Fair44x$321+5.1%
Expensive79x$579+89%

Historical ranges are pointers, not guarantees.

KRYS's PE is in its fair range at 42x. If earnings grow as analysts expect, today's price would be 35x next year's earnings, in its cheap range.

KRYS Forward outlook

MetricOutlook
Improving
Strong growth
Strong growth
Strongly improving
Limited
Moderate

Analysts expect strong earnings and revenue growth for KRYS, with profitability improving.

KRYS Risk to reward

ScenarioChangePrice
Upside+40%$429.30
Downside-17%$252.93

Calculated from the latest close: $305.68 on Nov 12.

KRYS's one-year upside scenario is more than twice its downside: +40% against −17%.

KRYS Earnings Per Share

Q4 2023: $0.39Q1 2024: $2.18Q2 2024: $3.96Q3 2024: $2.08Q4 2024: $3.00Q1 2025: $4.17Q2 2025: $4.93Q3 2025: $6.68Q4 2025: $6.84Q1 2026: $7.47Q2 2026: $7.97Q3 2026: $7.36Forward: $8.68
Q4 2023: $0.39Q1 2024: $2.18Q2 2024: $3.96Q3 2024: $2.08Q4 2024: $3.00Q1 2025: $4.17Q2 2025: $4.93Q3 2025: $6.68Q4 2025: $6.84Q1 2026: $7.47Q2 2026: $7.97Q3 2026: $7.36Forward: $8.68
QuarterTTM EPSYoY
Forward$8.68+18%
Q3 2026$7.36+10%
Q2 2026$7.97+62%
Q1 2026$7.47+79%
Q4 2025$6.84+128%
Q3 2025$6.68+221%
Q2 2025$4.93+24%
Q1 2025$4.17+91%
Q4 2024$3.00+669%

KRYS's earnings per share have climbed steadily: $7.36 over the past year, up 10% from the year before, and higher year over year for 13 quarters in a row.

KRYS Quarterly Revenue

Q4 2023: $42MQ1 2024: $45MQ2 2024: $70MQ3 2024: $84MQ4 2024: $91MQ1 2025: $88MQ2 2025: $96MQ3 2025: $98MQ4 2025: $107MQ1 2026: $116MQ2 2026: $119MQ3 2026: $127M
Q4 2023: $42MQ1 2024: $45MQ2 2024: $70MQ3 2024: $84MQ4 2024: $91MQ1 2025: $88MQ2 2025: $96MQ3 2025: $98MQ4 2025: $107MQ1 2026: $116MQ2 2026: $119MQ3 2026: $127M
QuarterRevenueYoY
Q3 2026$127.3M+30%
Q2 2026$119.2M+24%
Q1 2026$116.4M+32%
Q4 2025$107.1M+18%
Q3 2025$97.8M+17%
Q2 2025$96M+37%
Q1 2025$88.2M+95%
Q4 2024$91.1M+116%

KRYS's revenue has grown year over year every quarter since late 2024: $127M last quarter, up 30% from the same quarter a year ago.

KRYS Free Cash Flow

Q4 2023: −$9MQ1 2024: $15MQ2 2024: −$5MQ3 2024: $58MQ4 2024: $52MQ1 2025: $25MQ2 2025: $51MQ3 2025: $38MQ4 2025: $75MQ1 2026: $73MQ2 2026: $71MQ3 2026: $90M
Q4 2023: −$9MQ1 2024: $15MQ2 2024: −$5MQ3 2024: $58MQ4 2024: $52MQ1 2025: $25MQ2 2025: $51MQ3 2025: $38MQ4 2025: $75MQ1 2026: $73MQ2 2026: $71MQ3 2026: $90M
QuarterFree cash flowYoY
Q3 2026$90.3M+138%
Q2 2026$71.2M+40%
Q1 2026$73.2M+196%
Q4 2025$75.4M+45%
Q3 2025$38M-34%
Q2 2025$50.8M+$56.1M
Q1 2025$24.8M+69%
Q4 2024$52M+$61.1M

KRYS has burned cash in most quarters: $310M over the past year, up 87% from the year before.

KRYS Total Shares

Q4 2023: 28MQ1 2024: 29MQ2 2024: 30MQ3 2024: 30MQ4 2024: 30MQ1 2025: 30MQ2 2025: 30MQ3 2025: 30MQ4 2025: 30MQ1 2026: 31MQ2 2026: 31MQ3 2026: 31M
Q4 2023: 28MQ1 2024: 29MQ2 2024: 30MQ3 2024: 30MQ4 2024: 30MQ1 2025: 30MQ2 2025: 30MQ3 2025: 30MQ4 2025: 30MQ1 2026: 31MQ2 2026: 31MQ3 2026: 31M
PeriodChange %Net change
Quarterly+0.6%+181K shares
1 year+3.4%+1M shares
3 years+6.7%+1.9M shares
5 years+39%+8.6M shares
Available history+94%+14.9M shares

KRYS has 31M diluted shares, up 3.4% from a year ago.

KRYS Net Leverage

Q3 2024: -11.2xQ4 2024: -4.8xQ1 2025: -2.7xQ2 2025: -2.5xQ3 2025: -2.4xQ4 2025: -3.0xQ1 2026: -2.7xQ2 2026: -2.1xQ3 2026: -2.0x
Q3 2024: -11.2xQ4 2024: -4.8xQ1 2025: -2.7xQ2 2025: -2.5xQ3 2025: -2.4xQ4 2025: -3.0xQ1 2026: -2.7xQ2 2026: -2.1xQ3 2026: -2.0x
QuarterNet LeverageStatus
Q3 2026-2.0xNet Cash
Q2 2026-2.1xNet Cash
Q1 2026-2.7xNet Cash
Q4 2025-3.0xNet Cash
Q3 2025-2.4xNet Cash
Q2 2025-2.5xNet Cash
Q1 2025-2.7xNet Cash
Q4 2024-4.8xNet Cash

KRYS has more cash than debt.

KRYS Weekly Momentum

MetricValueStatus
RSI45.9Neutral
Stochastic31.3Neutral

KRYS's weekly RSI is 46 (neutral) and its Stochastic is 31 (neutral).

KRYS PE vs Healthcare Sector

MetricKRYSSector medianRelative
PE42x26x61% above
PE %422913 pts above

KRYS is trading at 42x earnings, a 61% premium to the Healthcare sector's median of 26x.

KRYS Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$320.84.7% below
20 week MA$336.99.3% below
50 week MA$300.81.6% above
100 week MA$231.732% above
200 week MA$184.566% above

KRYS has pulled back, but its long-term trend is still up: it's below its 8- and 20-week averages, but 66% above its 200-week average.

KRYS Yearly ROI

YearStart priceEnd priceROI
2020$60.2$60.6+0.7%
2021$60.6$72.3+19%
2022$72.3$76.6+5.9%
2023$76.6$124.1+62%
2024$124.1$159.3+28%
2025$159.3$252.2+58%
2026 YTD$252.2$305.7+21%

KRYS has finished every year since 2020 higher, and it's up 21% so far in 2026.

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