GYRE

Gyre Therapeutics, Inc.

37
Fundamentals36/ 100
Valuation50/ 100
Upside potential59/ 100
Risk potential30/ 100

GYRE trails on the overall score without a compensating advantage in the available component scores.

LLY

Eli Lilly and Company

78
Fundamentals85/ 100
Valuation62/ 100
Upside potential72/ 100
Risk potential15/ 100

LLY has the edge over GYRE overall, supported by stronger fundamentals and lower modeled downside.

GYRE Fundamentals

MetricStatus
Stable
Weak
Weak
Strong

GYRE's balance sheet is currently strong, and its revenue is stable, but its profitability and cash flow are weak.

LLY Fundamentals

MetricStatus
Healthy
Strong
Strong
Healthy

LLY's revenue, profitability, cash flow and balance sheet are all currently healthy.

GYRE PE Valuation

GYRE has no meaningful PE right now: it lost money over the past year.

LLY PE Valuation

CHEAPFAIREXPENSIVE37x74x111x147x
CHEAPFAIREXPENSIVE37x74x111x147x
LevelPEPriceVs current
Cheap27x$845-41%
Forward30x$1,427—
Current46x$1,427—
Fair48x$1,466+2.7%
Expensive85x$2,612+83%

Historical ranges are pointers, not guarantees.

LLY's PE is in its fair range at 46x. If earnings grow as analysts expect, today's price would be 30x next year's earnings, in its cheap range.

GYRE Forward outlook

MetricOutlook
--
Losses growing
Stable
Strongly weakening
Limited
Low

Analysts expect GYRE's losses to grow, with revenue holding steady. However, they disagree widely on these estimates.

LLY Forward outlook

MetricOutlook
Strongly improving
Strong growth
Strong growth
Strongly improving
Limited
Moderate

LLY has the edge over GYRE on the outlook, with more favorable earnings and revenue expectations.

GYRE Risk to reward

ScenarioChangePrice
Upside+43%$6.16
Downside-30%$3.00

Calculated from the latest close: $4.30 on Nov 12.

GYRE trails LLY on modeled risk to reward, with less potential upside relative to its potential downside.

LLY Risk to reward

ScenarioChangePrice
Upside+39%$1,988.49
Downside-15%$1,209.08

Calculated from the latest close: $1,427.28 on Nov 12.

LLY has a better modeled risk to reward balance than GYRE, with more potential upside relative to its potential downside.

GYRE Earnings Per Share

Q4 2023: $-2.81Q1 2024: $-2.93Q2 2024: $-1.87Q3 2024: $-1.26Q4 2024: $0.05Q2 2026: $-0.20Q3 2026: $-0.27
Q4 2023: $-2.81Q1 2024: $-2.93Q2 2024: $-1.87Q3 2024: $-1.26Q4 2024: $0.05Q2 2026: $-0.20Q3 2026: $-0.27
QuarterTTM EPSYoY
Q4 2024$0.05+$2.86
Q3 2024-$1.26+$19.44
Q2 2024-$1.87+$20.63
Q1 2024-$2.93-193%
Q4 2023-$2.81+$1.09
Q3 2023-$20.70-463%
Q2 2023-$22.50-$18.60
Q1 2023$3.15+$41.25

LLY has the stronger earnings trend. Trailing diluted EPS is down 114% for GYRE versus LLY up 51%.

LLY Earnings Per Share

Q4 2023: $5.80Q1 2024: $6.79Q2 2024: $8.12Q3 2024: $9.25Q4 2024: $11.71Q1 2025: $12.29Q2 2025: $15.30Q3 2025: $20.44Q4 2025: $22.95Q1 2026: $28.15Q2 2026: $29.80Q3 2026: $30.81Forward: $46.82
Q4 2023: $5.80Q1 2024: $6.79Q2 2024: $8.12Q3 2024: $9.25Q4 2024: $11.71Q1 2025: $12.29Q2 2025: $15.30Q3 2025: $20.44Q4 2025: $22.95Q1 2026: $28.15Q2 2026: $29.80Q3 2026: $30.81Forward: $46.82
QuarterTTM EPSYoY
Forward$46.82+52%
Q3 2026$30.81+51%
Q2 2026$29.80+95%
Q1 2026$28.15+129%
Q4 2025$22.95+96%
Q3 2025$20.44+121%
Q2 2025$15.30+88%
Q1 2025$12.29+81%
Q4 2024$11.71+102%

LLY's earnings per share have climbed steadily: $30.81 over the past year, up 51% from the year before, and higher year over year for 11 quarters in a row.

GYRE Quarterly Revenue

Q4 2023: --Q1 2024: $27MQ2 2024: $25MQ3 2024: $25MQ4 2024: $28MQ1 2025: $22MQ2 2025: $27MQ3 2025: $31MQ4 2025: $37MQ1 2026: $23MQ2 2026: $29MQ3 2026: $33M
Q4 2023: --Q1 2024: $27MQ2 2024: $25MQ3 2024: $25MQ4 2024: $28MQ1 2025: $22MQ2 2025: $27MQ3 2025: $31MQ4 2025: $37MQ1 2026: $23MQ2 2026: $29MQ3 2026: $33M
QuarterRevenueYoY
Q3 2026$32.9M+7.8%
Q2 2026$29.1M+8.7%
Q1 2026$22.5M+2.1%
Q4 2025$37.2M+33%
Q3 2025$30.6M+20%
Q2 2025$26.8M+6.1%
Q1 2025$22.1M-19%
Q1 2022$794K-46%

GYRE's revenue has grown year over year for six quarters in a row: $33M last quarter, up 7.8% from the same quarter a year ago.

LLY Quarterly Revenue

Q4 2023: $9.4BQ1 2024: $8.8BQ2 2024: $11.3BQ3 2024: $11.4BQ4 2024: $13.5BQ1 2025: $12.7BQ2 2025: $15.6BQ3 2025: $17.6BQ4 2025: $19.3BQ1 2026: $19.8BQ2 2026: $23BQ3 2026: $24.4B
Q4 2023: $9.4BQ1 2024: $8.8BQ2 2024: $11.3BQ3 2024: $11.4BQ4 2024: $13.5BQ1 2025: $12.7BQ2 2025: $15.6BQ3 2025: $17.6BQ4 2025: $19.3BQ1 2026: $19.8BQ2 2026: $23BQ3 2026: $24.4B
QuarterRevenueYoY
Q3 2026$24.4B+39%
Q2 2026$23B+48%
Q1 2026$19.8B+56%
Q4 2025$19.3B+43%
Q3 2025$17.6B+54%
Q2 2025$15.6B+38%
Q1 2025$12.7B+45%
Q4 2024$13.5B+45%

LLY has the edge over GYRE on sales, with more consistent year-over-year improvement.

GYRE Free Cash Flow

Q4 2023: --Q1 2024: $3MQ2 2024: −$7MQ3 2024: $1MQ4 2024: −$3MQ1 2025: −$251,000Q2 2025: $2MQ3 2025: $4MQ4 2025: −$6MQ1 2026: $3MQ2 2026: −$17MQ3 2026: −$5M
Q4 2023: --Q1 2024: $3MQ2 2024: −$7MQ3 2024: $1MQ4 2024: −$3MQ1 2025: −$251,000Q2 2025: $2MQ3 2025: $4MQ4 2025: −$6MQ1 2026: $3MQ2 2026: −$17MQ3 2026: −$5M
QuarterFree cash flowYoY
Q3 2026-$5M-224%
Q2 2026-$17M-1027%
Q1 2026$3M+$3.3M
Q4 2025-$5.8M-$3.1M
Q3 2025$4M+288%
Q2 2025$1.8M+$8.8M
Q1 2025-$251K-109%
Q3 2024$1M+$4.3M

GYRE has burned cash in most quarters: −$25M over the past year, against $3M the year before.

LLY Free Cash Flow

Q4 2023: −$1.4BQ1 2024: $180MQ2 2024: $241MQ3 2024: $2.4BQ4 2024: $978MQ1 2025: $156MQ2 2025: $1.4BQ3 2025: $6.7BQ4 2025: $678MQ1 2026: $3BQ2 2026: $7.8BQ3 2026: $8.2B
Q4 2023: −$1.4BQ1 2024: $180MQ2 2024: $241MQ3 2024: $2.4BQ4 2024: $978MQ1 2025: $156MQ2 2025: $1.4BQ3 2025: $6.7BQ4 2025: $678MQ1 2026: $3BQ2 2026: $7.8BQ3 2026: $8.2B
QuarterFree cash flowYoY
Q3 2026$8.2B+22%
Q2 2026$7.8B+458%
Q1 2026$3B+1826%
Q4 2025$677.9M-31%
Q3 2025$6.7B+186%
Q2 2025$1.4B+476%
Q1 2025$156.1M-13%
Q4 2024$977.8M+$2.4B

LLY has the edge over GYRE on cash generation, producing positive trailing cash flow while its opponent burns cash.

GYRE Total Shares

Q1 2024: 103MQ2 2024: 104MQ3 2024: 103MQ4 2024: 102MQ3 2025: 104MQ4 2025: 103MQ1 2026: 91MQ2 2026: 101MQ3 2026: 106M
Q1 2024: 103MQ2 2024: 104MQ3 2024: 103MQ4 2024: 102MQ3 2025: 104MQ4 2025: 103MQ1 2026: 91MQ2 2026: 101MQ3 2026: 106M
PeriodChange %Net change
Quarterly+5.6%+5.7M shares
1 year+2.2%+2.3M shares
3 years+4955%+104M shares
5 years+7124%+105M shares

GYRE has 106M diluted shares, up 2.2% from a year ago.

LLY Total Shares

Q4 2023: 903MQ1 2024: 904MQ2 2024: 904MQ3 2024: 905MQ4 2024: 904MQ1 2025: 901MQ2 2025: 900MQ3 2025: 899MQ4 2025: 899MQ1 2026: 896MQ2 2026: 894MQ3 2026: 893M
Q4 2023: 903MQ1 2024: 904MQ2 2024: 904MQ3 2024: 905MQ4 2024: 904MQ1 2025: 901MQ2 2025: 900MQ3 2025: 899MQ4 2025: 899MQ1 2026: 896MQ2 2026: 894MQ3 2026: 893M
PeriodChange %Net change
Quarterly0%-300K shares
1 year-0.6%-5.4M shares
3 years-0.7%-6.4M shares
5 years-1.9%-17.4M shares
Available history-4.5%-42.3M shares

LLY has the edge over GYRE on shareholder dilution, with a more favorable share count trend.

GYRE Net Leverage

Q4 2024: -0.7xQ1 2025: -1.3xQ2 2025: -3.2xQ3 2025: -2.8xQ4 2025: -2.7xQ1 2026: -15.1x
Q4 2024: -0.7xQ1 2025: -1.3xQ2 2025: -3.2xQ3 2025: -2.8xQ4 2025: -2.7xQ1 2026: -15.1x
QuarterNet LeverageStatus
Q1 2026-15.1xNet Cash
Q4 2025-2.7xNet Cash
Q3 2025-2.8xNet Cash
Q2 2025-3.2xNet Cash
Q1 2025-1.3xNet Cash
Q4 2024-0.7xNet Cash
Q1 2023-1.3xNet Cash
Q3 2022-2.0xNet Cash

GYRE has more cash than debt.

LLY Net Leverage

Q4 2023: 2.8xQ1 2024: 2.6xQ2 2024: 2.4xQ3 2024: 2.4xQ4 2024: 2.1xQ1 2025: 2.3xQ2 2025: 2.0xQ3 2025: 1.3xQ4 2025: 1.3xQ1 2026: 1.2xQ2 2026: 1.3xQ3 2026: 1.2x
Q4 2023: 2.8xQ1 2024: 2.6xQ2 2024: 2.4xQ3 2024: 2.4xQ4 2024: 2.1xQ1 2025: 2.3xQ2 2025: 2.0xQ3 2025: 1.3xQ4 2025: 1.3xQ1 2026: 1.2xQ2 2026: 1.3xQ3 2026: 1.2x
QuarterNet LeverageStatus
Q3 20261.2xHealthy
Q2 20261.3xHealthy
Q1 20261.2xHealthy
Q4 20251.3xHealthy
Q3 20251.3xHealthy
Q2 20252.0xHealthy
Q1 20252.3xModerate
Q4 20242.1xModerate

LLY's net debt is about 1.2 years of its operating earnings (EBITDA), about the same as a year ago.

GYRE Weekly Momentum

MetricValueStatus
RSI32.1Neutral
Stochastic10.3Oversold

GYRE's weekly RSI is 32 (neutral) and its Stochastic is 10 (oversold).

LLY Weekly Momentum

MetricValueStatus
RSI68.3Neutral
Stochastic84.1Overbought

LLY's weekly RSI is 68 (neutral) and its Stochastic is 84 (overbought).

GYRE PE vs Healthcare Sector

MetricGYRESector medianRelative
PEN/A26x—

GYRE has no meaningful PE right now: it lost money over the past year.

LLY PE vs Healthcare Sector

MetricLLYSector medianRelative
PE46x26x79% above
PE %482919 pts above

LLY is trading at 46x earnings, a 79% premium to the Healthcare sector's median of 26x.

GYRE Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$5.8827% below
20 week MA$6.3332% below
50 week MA$6.8938% below
100 week MA$7.9146% below
200 week MA$9.4254% below

GYRE is in a downtrend: it's below all five of its weekly moving averages, and 54% below its 200-week average.

LLY Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$1,279.412% above
20 week MA$1,218.817% above
50 week MA$1,102.229% above
100 week MA$954.150% above
200 week MA$797.579% above

LLY has the edge over GYRE on trend strength, trading above more of its moving averages.

GYRE Yearly ROI

YearStart priceEnd priceROI
2020$101.4$97.1-4.3%
2021$97.1$15.9-84%
2022$15.9$7.50-53%
2023$7.50$25.7+243%
2024$25.7$12.5-52%
2025$12.5$7.26-42%
2026 YTD$7.26$4.30-41%

GYRE's yearly returns have swung widely, from +243% in 2023 to −84% in 2021. It's down 41% so far in 2026.

LLY Yearly ROI

YearStart priceEnd priceROI
2020$131.5$166.7+27%
2021$166.7$273.1+64%
2022$273.1$367.9+35%
2023$367.9$582.9+58%
2024$582.9$783.2+34%
2025$783.2$1,077.8+38%
2026 YTD$1,077.8$1,427.3+32%

LLY has the edge over GYRE on returns for 2026, with the stronger performance.

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