CSTL

Castle Biosciences, Inc.

59
Fundamentals63/ 100
Valuation50/ 100
Upside potential60/ 100
Risk potential31/ 100

CSTL lost money over the past year, so it has no meaningful PE right now. Analysts expect losses to shrink.

CSTL Fundamentals

MetricStatus
Healthy
Under pressure
Under pressure
Strong

CSTL's revenue and balance sheet are currently healthy, but its profitability and cash flow are under pressure.

CSTL PE Valuation

CSTL has no meaningful PE right now: it lost money over the past year.

CSTL Forward outlook

MetricOutlook
--
Losses shrinking
Growth
Strongly improving
Limited
High

Analysts expect CSTL's losses to shrink, with revenue growing.

CSTL Risk to reward

ScenarioChangePrice
Upside+46%$50.41
Downside-31%$23.84

Calculated from the latest close: $34.50 on Nov 12.

CSTL's one-year upside scenario is somewhat larger than its downside: +46% against −31%.

CSTL Earnings Per Share

Q4 2023: $-2.14Q1 2024: $-1.13Q2 2024: $-0.12Q3 2024: $0.22Q4 2024: $0.62Q1 2025: $-0.19Q2 2025: $-0.35Q3 2025: $-0.45Q4 2025: $-0.83Q1 2026: $-0.42Q2 2026: $-0.64Q3 2026: $-0.75
Q4 2023: $-2.14Q1 2024: $-1.13Q2 2024: $-0.12Q3 2024: $0.22Q4 2024: $0.62Q1 2025: $-0.19Q2 2025: $-0.35Q3 2025: $-0.45Q4 2025: $-0.83Q1 2026: $-0.42Q2 2026: $-0.64Q3 2026: $-0.75
QuarterTTM EPSYoY
Q3 2026-$0.75-$0.30
Q2 2026-$0.64-$0.29
Q1 2026-$0.42-$0.23
Q4 2025-$0.83-234%
Q3 2025-$0.45-305%
Q2 2025-$0.35-$0.23
Q1 2025-$0.19+$0.94
Q4 2024$0.62+$2.76

CSTL is still losing money, but far less than before: $0.75 per share over the past year, against $3.35 at its worst in mid-2023.

CSTL Quarterly Revenue

Q4 2023: $66MQ1 2024: $73MQ2 2024: $87MQ3 2024: $86MQ4 2024: $86MQ1 2025: $88MQ2 2025: $86MQ3 2025: $83MQ4 2025: $87MQ1 2026: $84MQ2 2026: $104MQ3 2026: $103M
Q4 2023: $66MQ1 2024: $73MQ2 2024: $87MQ3 2024: $86MQ4 2024: $86MQ1 2025: $88MQ2 2025: $86MQ3 2025: $83MQ4 2025: $87MQ1 2026: $84MQ2 2026: $104MQ3 2026: $103M
QuarterRevenueYoY
Q3 2026$102.9M+24%
Q2 2026$103.5M+20%
Q1 2026$83.7M-4.9%
Q4 2025$87M+0.8%
Q3 2025$83M-3.2%
Q2 2025$86.2M-0.9%
Q1 2025$88M+21%
Q4 2024$86.3M+31%

CSTL's revenue is growing: $103M last quarter, up 24% from the same quarter a year ago.

CSTL Free Cash Flow

Q4 2023: $15MQ1 2024: −$16MQ2 2024: $19MQ3 2024: $17MQ4 2024: $17MQ1 2025: −$11MQ2 2025: $12MQ3 2025: $8MQ4 2025: $20MQ1 2026: −$35MQ2 2026: $7MQ3 2026: $12M
Q4 2023: $15MQ1 2024: −$16MQ2 2024: $19MQ3 2024: $17MQ4 2024: $17MQ1 2025: −$11MQ2 2025: $12MQ3 2025: $8MQ4 2025: $20MQ1 2026: −$35MQ2 2026: $7MQ3 2026: $12M
QuarterFree cash flowYoY
Q3 2026$12.2M+57%
Q2 2026$6.6M-43%
Q1 2026-$34.6M-$23.8M
Q4 2025$19.7M+18%
Q3 2025$7.8M-54%
Q2 2025$11.6M-38%
Q1 2025-$10.8M+$5.2M
Q4 2024$16.8M+14%

CSTL still generates free cash flow, though less than at its 2025 peak: $4M over the past year.

CSTL Total Shares

Q4 2023: 27MQ1 2024: 27MQ2 2024: 29MQ3 2024: 29MQ4 2024: 29MQ1 2025: 29MQ2 2025: 30MQ3 2025: 29MQ4 2025: 29MQ1 2026: 30MQ2 2026: 30MQ3 2026: 31M
Q4 2023: 27MQ1 2024: 27MQ2 2024: 29MQ3 2024: 29MQ4 2024: 29MQ1 2025: 29MQ2 2025: 30MQ3 2025: 29MQ4 2025: 29MQ1 2026: 30MQ2 2026: 30MQ3 2026: 31M
PeriodChange %Net change
Quarterly+0.8%+234K shares
1 year+5.4%+1.6M shares
3 years+14%+3.8M shares
5 years+21%+5.3M shares
Available history+64%+11.9M shares

CSTL has 31M diluted shares, up 5.4% from a year ago.

CSTL Net Leverage

Q3 2024: -6.8xQ4 2024: -4.5xQ1 2025: -2.8xQ2 2025: -3.7xQ3 2025: -9.6x
Q3 2024: -6.8xQ4 2024: -4.5xQ1 2025: -2.8xQ2 2025: -3.7xQ3 2025: -9.6x
QuarterNet LeverageStatus
Q3 2025-9.6xNet Cash
Q2 2025-3.7xNet Cash
Q1 2025-2.8xNet Cash
Q4 2024-4.5xNet Cash
Q3 2024-6.8xNet Cash
Q2 2020-19.8xNet Cash
Q1 2020-8.1xNet Cash
Q4 2019-9.6xNet Cash

CSTL has more cash than debt.

CSTL Weekly Momentum

MetricValueStatus
RSI57.0Neutral
Stochastic63.5Neutral

CSTL's weekly RSI is 57 (neutral) and its Stochastic is 63 (neutral).

CSTL PE vs Healthcare Sector

MetricCSTLSector medianRelative
PEN/A26x—

CSTL has no meaningful PE right now: it lost money over the past year.

CSTL Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$34.40.3% above
20 week MA$31.59.6% above
50 week MA$30.015% above
100 week MA$26.431% above
200 week MA$24.441% above

CSTL is in an uptrend: it's above all five of its weekly moving averages, and 41% above its 200-week average.

CSTL Yearly ROI

YearStart priceEnd priceROI
2020$34.0$71.3+110%
2021$71.3$42.6-40%
2022$42.6$23.2-45%
2023$23.2$21.6-7.1%
2024$21.6$26.8+24%
2025$26.8$39.4+47%
2026 YTD$39.4$34.5-12%

CSTL's yearly returns have swung widely, from +110% in 2020 to −45% in 2022. It's down 12% so far in 2026.

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