APRE

Aprea Therapeutics, Inc.

There isn't enough reported data to score APRE yet.

NVO

Novo Nordisk A/S

48
Fundamentals55/ 100
Valuation50/ 100
Upside potential58/ 100
Risk potential26/ 100

NVO's fundamentals are mixed: it turned 15% of its revenue into free cash flow, but its operating margin fell 3 points to 43%. Its PE isn't a useful guide right now because of how its recent earnings were reported.

APRE Fundamentals

MetricStatus
Unavailable
Under pressure
Unavailable
Unavailable

APRE's profitability is currently under pressure. There isn't enough data to rate its revenue, cash flow and balance sheet.

NVO Fundamentals

MetricStatus
Healthy
Strong
Stable
Healthy

NVO's revenue, profitability and balance sheet are currently healthy, and its cash flow is stable.

APRE PE Valuation

APRE has no meaningful PE right now: it lost money over the past year.

NVO PE Valuation

CHEAPFAIREXPENSIVE14x28x42x56x
CHEAPFAIREXPENSIVE14x28x42x56x
LevelPEPriceVs current
Current10x$40.65—
Cheap14x$53.56+32%
Fair27x$103+154%
Expensive39x$152+273%

Historical ranges are pointers, not guarantees.

NVO's PE is 10x, but its earnings don't support one, so it isn't a reliable read right now.

APRE Forward outlook

There aren't enough analyst estimates for APRE to show an outlook.

NVO Forward outlook

MetricOutlook
--
Stable
Growth
Weakening
Limited
Low

Analysts expect NVO's revenue to grow, but its profitability to weaken. However, they disagree widely on these estimates.

APRE Risk to reward

ScenarioChangePrice
UpsideUnknown—
DownsideUnknown—

Calculated from the latest close: $0.44 on Nov 12.

There is not enough scenario data to compare APRE and NVO's risk to reward.

NVO Risk to reward

ScenarioChangePrice
Upside+36%$55.48
Downside-26%$29.89

Calculated from the latest close: $40.65 on Nov 12.

There is not enough scenario data to compare APRE and NVO's risk to reward.

APRE Earnings Per Share

Q4 2023: $-3.95Q1 2024: $-3.28Q2 2024: $-2.99Q3 2024: $-2.78Q4 2024: $-2.45Q1 2025: $-2.44Q2 2025: $-2.39Q3 2025: $-2.22Q4 2025: $-1.93Q1 2026: $-1.49Q2 2026: $-1.03Q3 2026: $-0.65
Q4 2023: $-3.95Q1 2024: $-3.28Q2 2024: $-2.99Q3 2024: $-2.78Q4 2024: $-2.45Q1 2025: $-2.44Q2 2025: $-2.39Q3 2025: $-2.22Q4 2025: $-1.93Q1 2026: $-1.49Q2 2026: $-1.03Q3 2026: $-0.65
QuarterTTM EPSYoY
Q3 2026-$0.65+$1.57
Q2 2026-$1.03+$1.36
Q1 2026-$1.49+$0.95
Q4 2025-$1.93+$0.52
Q3 2025-$2.22+$0.56
Q2 2025-$2.39+$0.60
Q1 2025-$2.44+$0.84
Q4 2024-$2.45+$1.50

APRE is still losing money, but far less than before: $0.65 per share over the past year, against $110.00 at its worst in mid-2022.

NVO Earnings Per Share

Q3 2023: $2.48Q4 2023: $2.77Q1 2024: $2.96Q2 2024: $2.98Q3 2024: $3.15Q4 2024: $3.36Q1 2025: $3.49Q2 2025: $3.71Q3 2025: $3.47Q4 2025: $3.42Q1 2026: $4.07Q2 2026: $3.89
Q3 2023: $2.48Q4 2023: $2.77Q1 2024: $2.96Q2 2024: $2.98Q3 2024: $3.15Q4 2024: $3.36Q1 2025: $3.49Q2 2025: $3.71Q3 2025: $3.47Q4 2025: $3.42Q1 2026: $4.07Q2 2026: $3.89
QuarterTTM EPSYoY
Q2 2026$3.89+4.9%
Q1 2026$4.07+17%
Q4 2025$3.42+1.8%
Q3 2025$3.47+10%
Q2 2025$3.71+24%
Q1 2025$3.49+18%
Q4 2024$3.36+21%
Q3 2024$3.15+27%

NVO has the edge over APRE on earnings quality, reporting a profit while its opponent remains loss making.

APRE Quarterly Revenue

Q4 2023: --Q1 2024: --Q2 2024: --Q3 2024: --Q4 2024: --Q1 2025: --Q2 2025: --Q3 2025: --Q4 2025: --Q1 2026: --Q2 2026: --Q3 2026: --
Q4 2023: --Q1 2024: --Q2 2024: --Q3 2024: --Q4 2024: --Q1 2025: --Q2 2025: --Q3 2025: --Q4 2025: --Q1 2026: --Q2 2026: --Q3 2026: --

APRE and NVO do not have enough comparable growth data to identify a winner.

NVO Quarterly Revenue

Q3 2023: $8.7BQ4 2023: $9.8BQ1 2024: $9.7BQ2 2024: $10.1BQ3 2024: $10.6BQ4 2024: $12.7BQ1 2025: $11.6BQ2 2025: $11.4BQ3 2025: $11.1BQ4 2025: $11.8BQ1 2026: $14.4BQ2 2026: $11.7B
Q3 2023: $8.7BQ4 2023: $9.8BQ1 2024: $9.7BQ2 2024: $10.1BQ3 2024: $10.6BQ4 2024: $12.7BQ1 2025: $11.6BQ2 2025: $11.4BQ3 2025: $11.1BQ4 2025: $11.8BQ1 2026: $14.4BQ2 2026: $11.7B
QuarterRevenueYoY
Q2 2026$11.7B+2.1%
Q1 2026$14.4B+24%
Q4 2025$11.8B-7.6%
Q3 2025$11.1B+5.1%
Q2 2025$11.4B+13%
Q1 2025$11.6B+19%
Q4 2024$12.7B+30%
Q3 2024$10.6B+21%

NVO's revenue is growing: $11.7B last quarter, up 2.1% from the same quarter a year ago.

APRE Free Cash Flow

Q4 2023: −$4MQ1 2024: −$4MQ2 2024: −$4MQ3 2024: −$2MQ4 2024: −$4MQ1 2025: --Q2 2025: --Q3 2025: --Q4 2025: --Q1 2026: −$3MQ2 2026: --Q3 2026: −$4M
Q4 2023: −$4MQ1 2024: −$4MQ2 2024: −$4MQ3 2024: −$2MQ4 2024: −$4MQ1 2025: --Q2 2025: --Q3 2025: --Q4 2025: --Q1 2026: −$3MQ2 2026: --Q3 2026: −$4M
QuarterFree cash flowYoY
Q4 2024-$3.5M+$235.9K
Q2 2024-$3.6M-$432.2K
Q1 2024-$3.9M-$964.8K
Q4 2023-$3.7M+$273.7K
Q2 2023-$3.2M+$5.7M
Q1 2023-$3M+$2.5M
Q4 2022-$4M+$6.2M
Q4 2021-$10.2M+$3M

APRE has the stronger cash trend. Its trailing FCF is up 51% versus its history, compared with NVO at down 14%.

NVO Free Cash Flow

Q3 2023: $4.5BQ4 2023: −$1BQ1 2024: $788MQ2 2024: $5.5BQ3 2024: $4.7BQ4 2024: −$633MQ1 2025: $1.5BQ2 2025: $3.6BQ3 2025: $4.6BQ4 2025: −$5.4BQ1 2026: $1.8BQ2 2026: $6.3B
Q3 2023: $4.5BQ4 2023: −$1BQ1 2024: $788MQ2 2024: $5.5BQ3 2024: $4.7BQ4 2024: −$633MQ1 2025: $1.5BQ2 2025: $3.6BQ3 2025: $4.6BQ4 2025: −$5.4BQ1 2026: $1.8BQ2 2026: $6.3B
QuarterFree cash flowYoY
Q2 2026$6.3B+73%
Q1 2026$1.8B+20%
Q4 2025-$5.4B-$4.7B
Q3 2025$4.6B-2.1%
Q2 2025$3.6B-34%
Q1 2025$1.5B+89%
Q4 2024-$632.6M+$390.5M
Q3 2024$4.7B+3.3%

NVO still generates free cash flow, though less than at its 2026 peak: $7.3B over the past year.

APRE Total Shares

Q1 2024: 4MQ2 2024: 6MQ3 2024: 6MQ4 2024: 6MQ1 2025: 6MQ2 2025: 6MQ3 2025: 6MQ1 2026: 15MQ2 2026: 53MQ3 2026: 54M
Q1 2024: 4MQ2 2024: 6MQ3 2024: 6MQ4 2024: 6MQ1 2025: 6MQ2 2025: 6MQ3 2025: 6MQ1 2026: 15MQ2 2026: 53MQ3 2026: 54M
PeriodChange %Net change
Quarterly+0.4%+197K shares
1 year+782%+47.6M shares
3 years+1546%+50.4M shares
5 years+4980%+52.6M shares

APRE has 54M diluted shares, up 782% from a year ago.

NVO Total Shares

Q3 2023: 4.5BQ4 2023: 4.5BQ1 2024: 4.5BQ2 2024: 4.5BQ3 2024: 4.5BQ4 2024: 4.5BQ1 2025: 4.4BQ2 2025: 4.4BQ3 2025: 4.4BQ4 2025: 4.4BQ1 2026: 4.4BQ2 2026: 4.4B
Q3 2023: 4.5BQ4 2023: 4.5BQ1 2024: 4.5BQ2 2024: 4.5BQ3 2024: 4.5BQ4 2024: 4.5BQ1 2025: 4.4BQ2 2025: 4.4BQ3 2025: 4.4BQ4 2025: 4.4BQ1 2026: 4.4BQ2 2026: 4.4B
PeriodChange %Net change
Quarterly-0.3%-12.9M shares
1 year-0.2%-11M shares
3 years-1.5%-66.8M shares
5 years-3.8%-177M shares
Available history-6.5%-311M shares

NVO has the edge over APRE on shareholder dilution, with a more favorable share count trend.

APRE Net Leverage

APRE's operating earnings (EBITDA) were negative over the past year, so its debt can't be measured against them.

NVO Net Leverage

Q3 2023: -0.0xQ4 2023: 0.1xQ1 2024: 0.2xQ2 2024: 0.0xQ3 2024: -0.0xQ4 2024: 0.6xQ1 2025: 0.5xQ2 2025: 0.5xQ3 2025: 0.4xQ4 2025: 0.6xQ1 2026: 0.7xQ2 2026: 0.5x
Q3 2023: -0.0xQ4 2023: 0.1xQ1 2024: 0.2xQ2 2024: 0.0xQ3 2024: -0.0xQ4 2024: 0.6xQ1 2025: 0.5xQ2 2025: 0.5xQ3 2025: 0.4xQ4 2025: 0.6xQ1 2026: 0.7xQ2 2026: 0.5x
QuarterNet LeverageStatus
Q2 20260.5xVery low
Q1 20260.7xVery low
Q4 20250.6xVery low
Q3 20250.4xVery low
Q2 20250.5xVery low
Q1 20250.5xVery low
Q4 20240.6xVery low
Q3 2024-0.0xVery low

NVO's net debt is less than a year of its operating earnings (EBITDA).

APRE Weekly Momentum

MetricValueStatus
RSI32.9Neutral
Stochastic9.4Oversold

APRE's weekly RSI is 33 (neutral) and its Stochastic is 9 (oversold).

NVO Weekly Momentum

MetricValueStatus
RSI43.0Neutral
Stochastic27.0Neutral

NVO's weekly RSI is 43 (neutral) and its Stochastic is 27 (neutral).

APRE PE vs Healthcare Sector

APRE has no meaningful PE right now: it lost money over the past year.

NVO PE vs Healthcare Sector

MetricNVOSector medianRelative
PE10x26x60% below
PE %62923 pts below

NVO is trading at 10x earnings, a 60% discount to the Healthcare sector's median of 26x, though its earnings don't support one.

APRE Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$0.5824% below
20 week MA$0.6633% below
50 week MA$0.7743% below
100 week MA$1.4269% below
200 week MA$2.9885% below

APRE is in a downtrend: it's below all five of its weekly moving averages, and 85% below its 200-week average.

NVO Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$39.23.7% above
20 week MA$43.97.4% below
50 week MA$45.310% below
100 week MA$56.328% below
200 week MA$80.750% below

NVO has the edge over APRE on trend strength, trading above more of its moving averages.

APRE Yearly ROI

YearStart priceEnd priceROI
2020$990.6$501.8-49%
2021$501.8$67.4-87%
2022$67.4$7.42-89%
2023$7.42$4.70-37%
2024$4.70$3.37-28%
2025$3.37$0.98-71%
2026 YTD$0.98$0.44-55%

APRE has finished every year since 2020 lower, and it's down 55% so far in 2026.

NVO Yearly ROI

YearStart priceEnd priceROI
2020$29.1$34.7+19%
2021$34.7$54.2+56%
2022$54.2$67.0+24%
2023$67.0$103.5+54%
2024$103.5$87.4-16%
2025$87.4$52.4-40%
2026 YTD$52.4$40.7-22%

NVO has the edge over APRE on returns for 2026, with the stronger performance.

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