ALNY

Alnylam Pharmaceuticals, Inc.

65
Fundamentals91/ 100
Valuation57/ 100
Upside potential78/ 100
Risk potential16/ 100

ALNY has a slight edge over UNH overall, supported by stronger fundamentals and stronger modeled upside.

UNH

UnitedHealth Group Incorporated

62
Fundamentals51/ 100
Valuation56/ 100
Upside potential71/ 100
Risk potential15/ 100

UNH has slightly lower modeled downside risk, despite its lower overall score.

ALNY Fundamentals

MetricStatus
Healthy
Strong
Strong
Healthy

ALNY's revenue, profitability, cash flow and balance sheet are all currently healthy.

UNH Fundamentals

MetricStatus
Stable
Stable
Healthy
Healthy

UNH's cash flow and balance sheet are currently healthy, and its revenue and profitability are stable.

ALNY PE Valuation

CHEAPFAIREXPENSIVE518x1036x1554x2072x
CHEAPFAIREXPENSIVE518x1036x1554x2072x
LevelPEPriceVs current
Current8x$157—
Forward22x$157—
Cheap41x$800+411%
Fair76x$1,489+851%
Expensive1,731x$33,895+21538%

Historical ranges are pointers, not guarantees.

ALNY has the edge over UNH in the historical PE scenario, which offers more potential upside but is not a forecast.

UNH PE Valuation

CHEAPFAIREXPENSIVE10x21x31x42x
CHEAPFAIREXPENSIVE10x21x31x42x
LevelPEPriceVs current
Forward18x$405—
Cheap19x$325-20%
Fair23x$410+1.2%
Current23x$405—
Expensive30x$526+30%

Historical ranges are pointers, not guarantees.

UNH's PE is in its fair range at 23x. If earnings grow as analysts expect, today's price would be 18x next year's earnings, in its cheap range.

ALNY Forward outlook

MetricOutlook
Strongly deteriorating
Strong growth
Strong growth
Weakening
Limited
Low

Analysts expect strong earnings and revenue growth for ALNY, but weaker profitability. However, they disagree widely on these estimates.

UNH Forward outlook

MetricOutlook
Strongly improving
Strong growth
Stable
Improving
Moderate
Low

Analysts expect UNH's earnings to grow and its profitability to improve, with its revenue holding steady. However, they disagree widely on these estimates.

ALNY Risk to reward

ScenarioChangePrice
Upside+55%$242.30
Downside-16%$132.22

Calculated from the latest close: $156.65 on Nov 12.

ALNY has a better modeled risk to reward balance than UNH, with more potential upside relative to its potential downside.

UNH Risk to reward

ScenarioChangePrice
Upside+36%$550.65
Downside-15%$346.07

Calculated from the latest close: $405.13 on Nov 12.

UNH trails ALNY on modeled risk to reward, with less potential upside relative to its potential downside.

ALNY Earnings Per Share

Q4 2023: $-3.52Q1 2024: $-2.64Q2 2024: $-0.56Q3 2024: $-2.58Q4 2024: $-2.18Q1 2025: $-2.10Q2 2025: $-2.48Q3 2025: $0.23Q4 2025: $2.03Q1 2026: $3.98Q2 2026: $5.70Q3 2026: $19.58Forward: $7.04
Q4 2023: $-3.52Q1 2024: $-2.64Q2 2024: $-0.56Q3 2024: $-2.58Q4 2024: $-2.18Q1 2025: $-2.10Q2 2025: $-2.48Q3 2025: $0.23Q4 2025: $2.03Q1 2026: $3.98Q2 2026: $5.70Q3 2026: $19.58Forward: $7.04
QuarterTTM EPSYoY
Forward$7.04-64%
Q3 2026$19.58+8413%
Q2 2026$5.70+$8.18
Q1 2026$3.98+$6.08
Q4 2025$2.03+$4.21
Q3 2025$0.23+$2.81
Q2 2025-$2.48-$1.92
Q1 2025-$2.10+$0.54
Q4 2024-$2.18+$1.34

ALNY has the edge over UNH on earnings, with more consistent year-over-year improvement.

UNH Earnings Per Share

Q4 2023: $23.86Q1 2024: $16.38Q2 2024: $15.10Q3 2024: $15.37Q4 2024: $15.51Q1 2025: $23.89Q2 2025: $23.09Q3 2025: $19.17Q4 2025: $13.23Q1 2026: $13.28Q2 2026: $15.58Q3 2026: $17.55Forward: $22.65
Q4 2023: $23.86Q1 2024: $16.38Q2 2024: $15.10Q3 2024: $15.37Q4 2024: $15.51Q1 2025: $23.89Q2 2025: $23.09Q3 2025: $19.17Q4 2025: $13.23Q1 2026: $13.28Q2 2026: $15.58Q3 2026: $17.55Forward: $22.65
QuarterTTM EPSYoY
Forward$22.65+29%
Q3 2026$17.55-8.5%
Q2 2026$15.58-33%
Q1 2026$13.28-44%
Q4 2025$13.23-15%
Q3 2025$19.17+25%
Q2 2025$23.09+53%
Q1 2025$23.89+46%
Q4 2024$15.51-35%

UNH's earnings per share have fallen from their peak: $17.55 over the past year, against $23.89 in early 2025.

ALNY Quarterly Revenue

Q4 2023: $440MQ1 2024: $494MQ2 2024: $660MQ3 2024: $501MQ4 2024: $593MQ1 2025: $594MQ2 2025: $774MQ3 2025: $1.2BQ4 2025: $1.1BQ1 2026: $1.2BQ2 2026: $1.3BQ3 2026: $1.5B
Q4 2023: $440MQ1 2024: $494MQ2 2024: $660MQ3 2024: $501MQ4 2024: $593MQ1 2025: $594MQ2 2025: $774MQ3 2025: $1.2BQ4 2025: $1.1BQ1 2026: $1.2BQ2 2026: $1.3BQ3 2026: $1.5B
QuarterRevenueYoY
Q3 2026$1.5B+17%
Q2 2026$1.3B+67%
Q1 2026$1.2B+96%
Q4 2025$1.1B+85%
Q3 2025$1.2B+149%
Q2 2025$773.7M+17%
Q1 2025$594.2M+20%
Q4 2024$593.2M+35%

ALNY has the edge over UNH on sales, with more consistent year-over-year improvement.

UNH Quarterly Revenue

Q4 2023: $94.4BQ1 2024: $99.8BQ2 2024: $98.9BQ3 2024: $101BQ4 2024: $101BQ1 2025: $110BQ2 2025: $112BQ3 2025: $113BQ4 2025: $113BQ1 2026: $112BQ2 2026: $112BQ3 2026: $113B
Q4 2023: $94.4BQ1 2024: $99.8BQ2 2024: $98.9BQ3 2024: $101BQ4 2024: $101BQ1 2025: $110BQ2 2025: $112BQ3 2025: $113BQ4 2025: $113BQ1 2026: $112BQ2 2026: $112BQ3 2026: $113B
QuarterRevenueYoY
Q3 2026$112.7B-0.4%
Q2 2026$112B+0.4%
Q1 2026$111.7B+2%
Q4 2025$113.2B+12%
Q3 2025$113.2B+12%
Q2 2025$111.6B+13%
Q1 2025$109.6B+9.8%
Q4 2024$100.8B+6.8%

UNH's revenue has held roughly level: $113B last quarter, about level with the same quarter a year ago.

ALNY Free Cash Flow

Q4 2023: −$45MQ1 2024: −$94MQ2 2024: $116MQ3 2024: $40MQ4 2024: −$104MQ1 2025: −$127MQ2 2025: $139MQ3 2025: $313MQ4 2025: $140MQ1 2026: $49MQ2 2026: $292MQ3 2026: $271M
Q4 2023: −$45MQ1 2024: −$94MQ2 2024: $116MQ3 2024: $40MQ4 2024: −$104MQ1 2025: −$127MQ2 2025: $139MQ3 2025: $313MQ4 2025: $140MQ1 2026: $49MQ2 2026: $292MQ3 2026: $271M
QuarterFree cash flowYoY
Q3 2026$271.2M-13%
Q2 2026$292M+109%
Q1 2026$48.7M+$176M
Q4 2025$140.3M+$244M
Q3 2025$313M+692%
Q2 2025$139.4M+20%
Q1 2025-$127.3M-$32.8M
Q4 2024-$103.8M-$58.7M

ALNY has burned cash in most quarters: $752M over the past year, about three times what it generated the year before.

UNH Free Cash Flow

Q4 2023: −$6.2BQ1 2024: $401MQ2 2024: $5.9BQ3 2024: $13BQ4 2024: $1.5BQ1 2025: $4.6BQ2 2025: $6.3BQ3 2025: $5.1BQ4 2025: $160MQ1 2026: $8.1BQ2 2026: $10.3BQ3 2026: $4.3B
Q4 2023: −$6.2BQ1 2024: $401MQ2 2024: $5.9BQ3 2024: $13BQ4 2024: $1.5BQ1 2025: $4.6BQ2 2025: $6.3BQ3 2025: $5.1BQ4 2025: $160MQ1 2026: $8.1BQ2 2026: $10.3BQ3 2026: $4.3B
QuarterFree cash flowYoY
Q3 2026$4.3B-16%
Q2 2026$10.3B+63%
Q1 2026$8.1B+79%
Q4 2025$160M-89%
Q3 2025$5.1B-61%
Q2 2025$6.3B+6.9%
Q1 2025$4.6B+1037%
Q4 2024$1.5B+$7.6B

UNH still generates free cash flow, though less than at its 2022 peak: $22.8B over the past year.

ALNY Total Shares

Q4 2023: 125MQ1 2024: 126MQ2 2024: 127MQ3 2024: 129MQ4 2024: 128MQ1 2025: 130MQ2 2025: 131MQ3 2025: 137MQ4 2025: 135MQ1 2026: 138MQ2 2026: 138MQ3 2026: 138M
Q4 2023: 125MQ1 2024: 126MQ2 2024: 127MQ3 2024: 129MQ4 2024: 128MQ1 2025: 130MQ2 2025: 131MQ3 2025: 137MQ4 2025: 135MQ1 2026: 138MQ2 2026: 138MQ3 2026: 138M
PeriodChange %Net change
Quarterly-0.2%-241K shares
1 year+0.5%+692K shares
3 years+5.1%+6.7M shares
5 years+16%+18.9M shares
Available history+24%+26.3M shares

ALNY has 138M diluted shares, up 0.5% from a year ago.

UNH Total Shares

Q4 2023: 938MQ1 2024: 922MQ2 2024: 928MQ3 2024: 930MQ4 2024: 929MQ1 2025: 918MQ2 2025: 910MQ3 2025: 908MQ4 2025: 911MQ1 2026: 910MQ2 2026: 906MQ3 2026: 902M
Q4 2023: 938MQ1 2024: 922MQ2 2024: 928MQ3 2024: 930MQ4 2024: 929MQ1 2025: 918MQ2 2025: 910MQ3 2025: 908MQ4 2025: 911MQ1 2026: 910MQ2 2026: 906MQ3 2026: 902M
PeriodChange %Net change
Quarterly-0.4%-4M shares
1 year-0.7%-6M shares
3 years-3.6%-34M shares
5 years-5.5%-53M shares
Available history-6.6%-64M shares

UNH has the edge over ALNY on shareholder dilution, with a more favorable share count trend.

ALNY Net Leverage

Q2 2024: -6.1xQ3 2025: -4.6xQ4 2025: -3.0xQ1 2026: -2.1xQ2 2026: -1.6xQ3 2026: -1.7x
Q2 2024: -6.1xQ3 2025: -4.6xQ4 2025: -3.0xQ1 2026: -2.1xQ2 2026: -1.6xQ3 2026: -1.7x
QuarterNet LeverageStatus
Q3 2026-1.7xNet Cash
Q2 2026-1.6xNet Cash
Q1 2026-2.1xNet Cash
Q4 2025-3.0xNet Cash
Q3 2025-4.6xNet Cash
Q2 2024-6.1xNet Cash

ALNY has the edge over UNH on leverage, with a lower net debt burden relative to earnings.

UNH Net Leverage

Q4 2023: 1.0xQ1 2024: 1.3xQ2 2024: 1.4xQ3 2024: 1.3xQ4 2024: 1.4xQ1 2025: 1.3xQ2 2025: 1.5xQ3 2025: 1.7xQ4 2025: 2.3xQ1 2026: 2.2xQ2 2026: 1.7xQ3 2026: 1.7x
Q4 2023: 1.0xQ1 2024: 1.3xQ2 2024: 1.4xQ3 2024: 1.3xQ4 2024: 1.4xQ1 2025: 1.3xQ2 2025: 1.5xQ3 2025: 1.7xQ4 2025: 2.3xQ1 2026: 2.2xQ2 2026: 1.7xQ3 2026: 1.7x
QuarterNet LeverageStatus
Q3 20261.7xHealthy
Q2 20261.7xHealthy
Q1 20262.2xModerate
Q4 20252.3xModerate
Q3 20251.7xHealthy
Q2 20251.5xHealthy
Q1 20251.3xHealthy
Q4 20241.4xHealthy

UNH's net debt is about 1.7 years of its operating earnings (EBITDA), about the same as a year ago.

ALNY Weekly Momentum

MetricValueStatus
RSI28.6Oversold
Stochastic2.9Oversold

ALNY's weekly RSI is 29 (oversold) and its Stochastic is 3 (oversold).

UNH Weekly Momentum

MetricValueStatus
RSI56.4Neutral
Stochastic60.0Neutral

UNH's weekly RSI is 56 (neutral) and its Stochastic is 60 (neutral).

ALNY PE vs Healthcare Sector

MetricALNYSector medianRelative
PE8x26x69% below
PE %22927 pts below

ALNY has the edge over UNH on valuation relative to its sector.

UNH PE vs Healthcare Sector

MetricUNHSector medianRelative
PE23x26x11% below
PE %472918 pts above

UNH is trading at 23x earnings, a 11% discount to the Healthcare sector's median of 26x.

ALNY Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$205.224% below
20 week MA$233.733% below
50 week MA$293.047% below
100 week MA$314.650% below
200 week MA$257.739% below

ALNY is in a downtrend: it's below all five of its weekly moving averages, and 39% below its 200-week average.

UNH Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$394.22.8% above
20 week MA$400.51.2% above
50 week MA$361.212% above
100 week MA$376.07.8% above
200 week MA$446.69.3% below

UNH has the edge over ALNY on trend strength, trading above more of its moving averages.

ALNY Yearly ROI

YearStart priceEnd priceROI
2020$117.5$137.6+17%
2021$137.6$194.4+41%
2022$194.4$237.9+22%
2023$237.9$191.4-20%
2024$191.4$238.0+24%
2025$238.0$400.6+68%
2026 YTD$400.6$156.7-61%

ALNY is down 61% so far in 2026, after finishing higher in five of the previous six years.

UNH Yearly ROI

YearStart priceEnd priceROI
2020$296.0$340.8+15%
2021$340.8$495.4+45%
2022$495.4$531.3+7.3%
2023$531.3$526.5-0.9%
2024$526.5$510.0-3.1%
2025$510.0$331.8-35%
2026 YTD$331.8$405.1+22%

UNH has the edge over ALNY on returns for 2026, with the stronger performance.

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