AGEN

Agenus Inc.

47
Fundamentals64/ 100
Valuation50/ 100
Upside potential64/ 100
Risk potential45/ 100

AGEN offers stronger fundamentals, but that advantage does not outweigh its weaker overall profile.

NVO

Novo Nordisk A/S

48
Fundamentals55/ 100
Valuation50/ 100
Upside potential58/ 100
Risk potential26/ 100

NVO has a slight edge over AGEN overall, supported by lower modeled downside.

AGEN Fundamentals

MetricStatus
Healthy
Strong
Weak
Strong

AGEN's revenue, profitability and balance sheet are currently healthy, but its cash flow is weak.

NVO Fundamentals

MetricStatus
Healthy
Strong
Stable
Healthy

NVO's revenue, profitability and balance sheet are currently healthy, and its cash flow is stable.

AGEN PE Valuation

CHEAPFAIREXPENSIVE4.6x9.3x14x19x
CHEAPFAIREXPENSIVE4.6x9.3x14x19x
LevelPEPriceVs current
Cheap2.1x$1.52-78%
Fair3.1x$2.20-68%
Current9.7x$6.87—
Expensive15x$10.89+58%

Historical ranges are pointers, not guarantees.

AGEN's PE is 9.7x, but its earnings don't support one, so it isn't a reliable read right now.

NVO PE Valuation

CHEAPFAIREXPENSIVE14x28x42x56x
CHEAPFAIREXPENSIVE14x28x42x56x
LevelPEPriceVs current
Current10x$40.65—
Cheap14x$53.56+32%
Fair27x$103+154%
Expensive39x$152+273%

Historical ranges are pointers, not guarantees.

NVO has the edge over AGEN in the historical PE scenario, which offers more potential upside but is not a forecast.

AGEN Forward outlook

MetricOutlook
--
Turning to a loss
Strong decline
--
Limited
High

Analysts expect AGEN's earnings and revenue to decline, though with profitability holding steady.

NVO Forward outlook

MetricOutlook
--
Stable
Growth
Weakening
Limited
Low

Analysts expect NVO's revenue to grow, but its profitability to weaken. However, they disagree widely on these estimates.

AGEN Risk to reward

ScenarioChangePrice
Upside+82%$12.51
Downside-45%$3.75

Calculated from the latest close: $6.87 on Nov 12.

AGEN has a better modeled risk to reward balance than NVO, with more potential upside relative to its potential downside.

NVO Risk to reward

ScenarioChangePrice
Upside+36%$55.48
Downside-26%$29.89

Calculated from the latest close: $40.65 on Nov 12.

NVO trails AGEN on modeled risk to reward, with less potential upside relative to its potential downside.

AGEN Earnings Per Share

Q4 2024: $-10.59Q1 2025: $-8.58Q2 2025: $-7.06Q3 2025: $-2.04Q4 2025: $-0.41Q1 2026: $1.64Q2 2026: $2.63Q3 2026: $0.71
Q4 2024: $-10.59Q1 2025: $-8.58Q2 2025: $-7.06Q3 2025: $-2.04Q4 2025: $-0.41Q1 2026: $1.64Q2 2026: $2.63Q3 2026: $0.71
QuarterTTM EPSYoY
Q3 2026$0.71+$2.75
Q2 2026$2.63+$9.69
Q1 2026$1.64+$10.22
Q4 2025-$0.41+$10.18
Q3 2022-$14.52-$12.16
Q2 2022$3.34+$25.32
Q1 2022-$0.59+$19.63
Q4 2021-$2.16+$18.84

AGEN has returned to profit: it earned $0.71 per share over the past year, after losing money the year before.

NVO Earnings Per Share

Q3 2023: $2.48Q4 2023: $2.77Q1 2024: $2.96Q2 2024: $2.98Q3 2024: $3.15Q4 2024: $3.36Q1 2025: $3.49Q2 2025: $3.71Q3 2025: $3.47Q4 2025: $3.42Q1 2026: $4.07Q2 2026: $3.89
Q3 2023: $2.48Q4 2023: $2.77Q1 2024: $2.96Q2 2024: $2.98Q3 2024: $3.15Q4 2024: $3.36Q1 2025: $3.49Q2 2025: $3.71Q3 2025: $3.47Q4 2025: $3.42Q1 2026: $4.07Q2 2026: $3.89
QuarterTTM EPSYoY
Q2 2026$3.89+4.9%
Q1 2026$4.07+17%
Q4 2025$3.42+1.8%
Q3 2025$3.47+10%
Q2 2025$3.71+24%
Q1 2025$3.49+18%
Q4 2024$3.36+21%
Q3 2024$3.15+27%

NVO has the edge over AGEN on earnings, with more consistent year-over-year improvement.

AGEN Quarterly Revenue

Q4 2023: $84MQ1 2024: $28MQ2 2024: $24MQ3 2024: $25MQ4 2024: $27MQ1 2025: $24MQ2 2025: $26MQ3 2025: $30MQ4 2025: $34MQ1 2026: $34MQ2 2026: $35MQ3 2026: $31M
Q4 2023: $84MQ1 2024: $28MQ2 2024: $24MQ3 2024: $25MQ4 2024: $27MQ1 2025: $24MQ2 2025: $26MQ3 2025: $30MQ4 2025: $34MQ1 2026: $34MQ2 2026: $35MQ3 2026: $31M
QuarterRevenueYoY
Q3 2026$31.5M+4.1%
Q2 2026$34.5M+34%
Q1 2026$33.7M+40%
Q4 2025$34.2M+27%
Q3 2025$30.2M+20%
Q2 2025$25.7M+9.3%
Q1 2025$24.1M-14%
Q4 2024$26.8M-68%

AGEN's revenue has grown year over year for six quarters in a row: $31M last quarter, up 4.1% from the same quarter a year ago.

NVO Quarterly Revenue

Q3 2023: $8.7BQ4 2023: $9.8BQ1 2024: $9.7BQ2 2024: $10.1BQ3 2024: $10.6BQ4 2024: $12.7BQ1 2025: $11.6BQ2 2025: $11.4BQ3 2025: $11.1BQ4 2025: $11.8BQ1 2026: $14.4BQ2 2026: $11.7B
Q3 2023: $8.7BQ4 2023: $9.8BQ1 2024: $9.7BQ2 2024: $10.1BQ3 2024: $10.6BQ4 2024: $12.7BQ1 2025: $11.6BQ2 2025: $11.4BQ3 2025: $11.1BQ4 2025: $11.8BQ1 2026: $14.4BQ2 2026: $11.7B
QuarterRevenueYoY
Q2 2026$11.7B+2.1%
Q1 2026$14.4B+24%
Q4 2025$11.8B-7.6%
Q3 2025$11.1B+5.1%
Q2 2025$11.4B+13%
Q1 2025$11.6B+19%
Q4 2024$12.7B+30%
Q3 2024$10.6B+21%

NVO has the edge over AGEN on sales, with more consistent year-over-year improvement.

AGEN Free Cash Flow

Q4 2023: −$41MQ1 2024: −$38MQ2 2024: −$39MQ3 2024: −$53MQ4 2024: −$29MQ1 2025: −$26MQ2 2025: −$20MQ3 2025: −$15MQ4 2025: −$17MQ1 2026: −$36MQ2 2026: −$31MQ3 2026: −$20M
Q4 2023: −$41MQ1 2024: −$38MQ2 2024: −$39MQ3 2024: −$53MQ4 2024: −$29MQ1 2025: −$26MQ2 2025: −$20MQ3 2025: −$15MQ4 2025: −$17MQ1 2026: −$36MQ2 2026: −$31MQ3 2026: −$20M
QuarterFree cash flowYoY
Q3 2026-$20.1M-$5.4M
Q2 2026-$31.2M-$11M
Q1 2026-$36M-$10.3M
Q4 2025-$16.6M+$12.1M
Q3 2025-$14.7M+$38.6M
Q2 2025-$20.2M+$18.4M
Q1 2025-$25.6M+$12.6M
Q4 2024-$28.7M+$11.9M

AGEN has burned cash in almost every quarter: −$104M over the past year, against −$89M the year before.

NVO Free Cash Flow

Q3 2023: $4.5BQ4 2023: −$1BQ1 2024: $788MQ2 2024: $5.5BQ3 2024: $4.7BQ4 2024: −$633MQ1 2025: $1.5BQ2 2025: $3.6BQ3 2025: $4.6BQ4 2025: −$5.4BQ1 2026: $1.8BQ2 2026: $6.3B
Q3 2023: $4.5BQ4 2023: −$1BQ1 2024: $788MQ2 2024: $5.5BQ3 2024: $4.7BQ4 2024: −$633MQ1 2025: $1.5BQ2 2025: $3.6BQ3 2025: $4.6BQ4 2025: −$5.4BQ1 2026: $1.8BQ2 2026: $6.3B
QuarterFree cash flowYoY
Q2 2026$6.3B+73%
Q1 2026$1.8B+20%
Q4 2025-$5.4B-$4.7B
Q3 2025$4.6B-2.1%
Q2 2025$3.6B-34%
Q1 2025$1.5B+89%
Q4 2024-$632.6M+$390.5M
Q3 2024$4.7B+3.3%

NVO has the edge over AGEN on cash generation, producing positive trailing cash flow while its opponent burns cash.

AGEN Total Shares

Q1 2024: 20MQ2 2024: 21MQ3 2024: 22MQ4 2024: 21MQ1 2025: 24MQ2 2025: 28MQ3 2025: 33MQ1 2026: 38MQ2 2026: 41MQ3 2026: 83M
Q1 2024: 20MQ2 2024: 21MQ3 2024: 22MQ4 2024: 21MQ1 2025: 24MQ2 2025: 28MQ3 2025: 33MQ1 2026: 38MQ2 2026: 41MQ3 2026: 83M
PeriodChange %Net change
Quarterly+101%+41.9M shares
1 year+196%+55.2M shares
3 years+795%+74M shares

AGEN has 83M diluted shares, up 196% from a year ago.

NVO Total Shares

Q3 2023: 4.5BQ4 2023: 4.5BQ1 2024: 4.5BQ2 2024: 4.5BQ3 2024: 4.5BQ4 2024: 4.5BQ1 2025: 4.4BQ2 2025: 4.4BQ3 2025: 4.4BQ4 2025: 4.4BQ1 2026: 4.4BQ2 2026: 4.4B
Q3 2023: 4.5BQ4 2023: 4.5BQ1 2024: 4.5BQ2 2024: 4.5BQ3 2024: 4.5BQ4 2024: 4.5BQ1 2025: 4.4BQ2 2025: 4.4BQ3 2025: 4.4BQ4 2025: 4.4BQ1 2026: 4.4BQ2 2026: 4.4B
PeriodChange %Net change
Quarterly-0.3%-12.9M shares
1 year-0.2%-11M shares
3 years-1.5%-66.8M shares
5 years-3.8%-177M shares
Available history-6.5%-311M shares

NVO has the edge over AGEN on shareholder dilution, with a more favorable share count trend.

AGEN Net Leverage

Q1 2026: -0.3xQ2 2026: 0.3xQ3 2026: -0.7x
Q1 2026: -0.3xQ2 2026: 0.3xQ3 2026: -0.7x
QuarterNet LeverageStatus
Q3 2026-0.7xNet Cash
Q2 20260.3xVery low
Q1 2026-0.3xNet Cash
Q2 2022-3.6xNet Cash
Q1 2022-6.1xNet Cash
Q4 2021-8.6xNet Cash
Q3 2021-3.7xNet Cash

AGEN has the edge over NVO on leverage, with a lower net debt burden relative to earnings.

NVO Net Leverage

Q3 2023: -0.0xQ4 2023: 0.1xQ1 2024: 0.2xQ2 2024: 0.0xQ3 2024: -0.0xQ4 2024: 0.6xQ1 2025: 0.5xQ2 2025: 0.5xQ3 2025: 0.4xQ4 2025: 0.6xQ1 2026: 0.7xQ2 2026: 0.5x
Q3 2023: -0.0xQ4 2023: 0.1xQ1 2024: 0.2xQ2 2024: 0.0xQ3 2024: -0.0xQ4 2024: 0.6xQ1 2025: 0.5xQ2 2025: 0.5xQ3 2025: 0.4xQ4 2025: 0.6xQ1 2026: 0.7xQ2 2026: 0.5x
QuarterNet LeverageStatus
Q2 20260.5xVery low
Q1 20260.7xVery low
Q4 20250.6xVery low
Q3 20250.4xVery low
Q2 20250.5xVery low
Q1 20250.5xVery low
Q4 20240.6xVery low
Q3 2024-0.0xVery low

NVO's net debt is less than a year of its operating earnings (EBITDA).

AGEN Weekly Momentum

MetricValueStatus
RSI54.3Neutral
Stochastic22.9Neutral

AGEN's weekly RSI is 54 (neutral) and its Stochastic is 23 (neutral).

NVO Weekly Momentum

MetricValueStatus
RSI43.0Neutral
Stochastic27.0Neutral

NVO's weekly RSI is 43 (neutral) and its Stochastic is 27 (neutral).

AGEN PE vs Healthcare Sector

MetricAGENSector medianRelative
PE9.7x26x62% below
PE %642935 pts above

AGEN has the edge over NVO on valuation relative to its sector.

NVO PE vs Healthcare Sector

MetricNVOSector medianRelative
PE10x26x60% below
PE %62923 pts below

NVO is trading at 10x earnings, a 60% discount to the Healthcare sector's median of 26x, though its earnings don't support one.

AGEN Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$7.224.8% below
20 week MA$6.810.9% above
50 week MA$4.7844% above
100 week MA$4.3060% above
200 week MA$11.741% below

AGEN has the edge over NVO on trend strength, trading above more of its moving averages.

NVO Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$39.23.7% above
20 week MA$43.97.4% below
50 week MA$45.310% below
100 week MA$56.328% below
200 week MA$80.750% below

NVO has bounced recently, but its long-term trend is still down: it's above its 8-week average, but 50% below its 200-week average.

AGEN Yearly ROI

YearStart priceEnd priceROI
2020$82.8$67.7-18%
2021$67.7$71.6+5.8%
2022$71.6$49.1-32%
2023$49.1$16.6-66%
2024$16.6$2.75-83%
2025$2.75$3.31+20%
2026 YTD$3.31$6.87+108%

AGEN has the edge over NVO on returns for 2026, with the stronger performance.

NVO Yearly ROI

YearStart priceEnd priceROI
2020$29.1$34.7+19%
2021$34.7$54.2+56%
2022$54.2$67.0+24%
2023$67.0$103.5+54%
2024$103.5$87.4-16%
2025$87.4$52.4-40%
2026 YTD$52.4$40.7-22%

NVO has finished higher in four of the last six years, two of them by more than 50%. It's down 22% so far in 2026.

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