ACIU

AC Immune S.A.

39
Fundamentals12/ 100
Valuation50/ 100
Upside potential60/ 100
Risk potential31/ 100

ACIU offers stronger modeled upside, but that advantage does not outweigh its weaker overall profile.

NVO

Novo Nordisk A/S

48
Fundamentals55/ 100
Valuation50/ 100
Upside potential58/ 100
Risk potential26/ 100

NVO has the edge over ACIU overall, supported by stronger fundamentals and lower modeled downside.

ACIU Fundamentals

MetricStatus
Under pressure
Weak
Under pressure
Strong

ACIU's balance sheet is currently strong, but its revenue, profitability and cash flow are under pressure.

NVO Fundamentals

MetricStatus
Healthy
Strong
Stable
Healthy

NVO's revenue, profitability and balance sheet are currently healthy, and its cash flow is stable.

ACIU PE Valuation

ACIU has no meaningful PE right now: it lost money over the past year.

NVO PE Valuation

CHEAPFAIREXPENSIVE14x28x42x56x
CHEAPFAIREXPENSIVE14x28x42x56x
LevelPEPriceVs current
Current10x$40.65—
Cheap14x$53.56+32%
Fair27x$103+154%
Expensive39x$152+273%

Historical ranges are pointers, not guarantees.

NVO's PE is 10x, but its earnings don't support one, so it isn't a reliable read right now.

ACIU Forward outlook

MetricOutlook
--
Returning to profit
Strong growth
--
Limited
High

Analysts expect ACIU to return to profit, with revenue growing.

NVO Forward outlook

MetricOutlook
--
Stable
Growth
Weakening
Limited
Low

Analysts expect NVO's revenue to grow, but its profitability to weaken. However, they disagree widely on these estimates.

ACIU Risk to reward

ScenarioChangePrice
Upside+46%$3.12
Downside-31%$1.48

Calculated from the latest close: $2.14 on Nov 12.

ACIU has a better modeled risk to reward balance than NVO, with more potential upside relative to its potential downside.

NVO Risk to reward

ScenarioChangePrice
Upside+36%$55.48
Downside-26%$29.89

Calculated from the latest close: $40.65 on Nov 12.

NVO trails ACIU on modeled risk to reward, with less potential upside relative to its potential downside.

ACIU Earnings Per Share

Q3 2023: $-0.98Q4 2023: $-0.78Q1 2024: $-0.74Q2 2024: $-0.78Q3 2024: $-0.50Q4 2024: $-0.61Q1 2025: $-0.63Q2 2025: $-0.60Q3 2025: $-0.85Q4 2025: $-0.84Q1 2026: $-0.79Q2 2026: $-0.52
Q3 2023: $-0.98Q4 2023: $-0.78Q1 2024: $-0.74Q2 2024: $-0.78Q3 2024: $-0.50Q4 2024: $-0.61Q1 2025: $-0.63Q2 2025: $-0.60Q3 2025: $-0.85Q4 2025: $-0.84Q1 2026: $-0.79Q2 2026: $-0.52
QuarterTTM EPSYoY
Q2 2026-$0.52+$0.08
Q1 2026-$0.79-$0.16
Q4 2025-$0.84-$0.23
Q3 2025-$0.85-$0.35
Q2 2025-$0.60+$0.18
Q1 2025-$0.63+$0.11
Q4 2024-$0.61+$0.17
Q3 2024-$0.50+$0.48

ACIU is still losing money, but far less than before: $0.52 per share over the past year, against $1.23 at its worst in mid-2021.

NVO Earnings Per Share

Q3 2023: $2.48Q4 2023: $2.77Q1 2024: $2.96Q2 2024: $2.98Q3 2024: $3.15Q4 2024: $3.36Q1 2025: $3.49Q2 2025: $3.71Q3 2025: $3.47Q4 2025: $3.42Q1 2026: $4.07Q2 2026: $3.89
Q3 2023: $2.48Q4 2023: $2.77Q1 2024: $2.96Q2 2024: $2.98Q3 2024: $3.15Q4 2024: $3.36Q1 2025: $3.49Q2 2025: $3.71Q3 2025: $3.47Q4 2025: $3.42Q1 2026: $4.07Q2 2026: $3.89
QuarterTTM EPSYoY
Q2 2026$3.89+4.9%
Q1 2026$4.07+17%
Q4 2025$3.42+1.8%
Q3 2025$3.47+10%
Q2 2025$3.71+24%
Q1 2025$3.49+18%
Q4 2024$3.36+21%
Q3 2024$3.15+27%

NVO has the edge over ACIU on earnings quality, reporting a profit while its opponent remains loss making.

ACIU Quarterly Revenue

Q3 2023: $0Q4 2023: $18MQ1 2024: $0Q2 2024: $827,043Q3 2024: $31MQ4 2024: $1MQ1 2025: $1MQ2 2025: $2MQ3 2025: $1MQ4 2025: $406,900Q1 2026: $1MQ2 2026: $18M
Q3 2023: $0Q4 2023: $18MQ1 2024: $0Q2 2024: $827,043Q3 2024: $31MQ4 2024: $1MQ1 2025: $1MQ2 2025: $2MQ3 2025: $1MQ4 2025: $406,900Q1 2026: $1MQ2 2026: $18M
QuarterRevenueYoY
Q2 2026$18.2M+1057%
Q1 2026$1.3M+13%
Q4 2025$406.9K-70%
Q3 2025$1.1M-96%
Q2 2025$1.6M+90%
Q4 2024$1.4M-92%
Q4 2023$17.8M+1479813%
Q4 2020$1.1M+9.8%

ACIU's revenue is recovering but still below its 2019 peak: $18M last quarter, up 1057% from the same quarter a year ago.

NVO Quarterly Revenue

Q3 2023: $8.7BQ4 2023: $9.8BQ1 2024: $9.7BQ2 2024: $10.1BQ3 2024: $10.6BQ4 2024: $12.7BQ1 2025: $11.6BQ2 2025: $11.4BQ3 2025: $11.1BQ4 2025: $11.8BQ1 2026: $14.4BQ2 2026: $11.7B
Q3 2023: $8.7BQ4 2023: $9.8BQ1 2024: $9.7BQ2 2024: $10.1BQ3 2024: $10.6BQ4 2024: $12.7BQ1 2025: $11.6BQ2 2025: $11.4BQ3 2025: $11.1BQ4 2025: $11.8BQ1 2026: $14.4BQ2 2026: $11.7B
QuarterRevenueYoY
Q2 2026$11.7B+2.1%
Q1 2026$14.4B+24%
Q4 2025$11.8B-7.6%
Q3 2025$11.1B+5.1%
Q2 2025$11.4B+13%
Q1 2025$11.6B+19%
Q4 2024$12.7B+30%
Q3 2024$10.6B+21%

NVO has the edge over ACIU on sales, with more consistent year-over-year improvement.

ACIU Free Cash Flow

Q3 2023: −$16MQ4 2023: −$20MQ1 2024: $932,982Q2 2024: $88MQ3 2024: −$17MQ4 2024: $7MQ1 2025: −$23MQ2 2025: −$19MQ3 2025: −$22MQ4 2025: −$20MQ1 2026: $0Q2 2026: $0
Q3 2023: −$16MQ4 2023: −$20MQ1 2024: $932,982Q2 2024: $88MQ3 2024: −$17MQ4 2024: $7MQ1 2025: −$23MQ2 2025: −$19MQ3 2025: −$22MQ4 2025: −$20MQ1 2026: $0Q2 2026: $0
QuarterFree cash flowYoY
Q2 2026$0+$19.2M
Q1 2026$0+$23.1M
Q4 2025-$19.9M-383%
Q3 2025-$22.1M-$4.9M
Q2 2025-$19.2M-122%
Q1 2025-$23.1M-2575%
Q4 2024$7M+$26.7M
Q3 2024-$17.2M-$881.2K

ACIU has burned cash in most quarters: −$42M over the past year, against −$53M the year before.

NVO Free Cash Flow

Q3 2023: $4.5BQ4 2023: −$1BQ1 2024: $788MQ2 2024: $5.5BQ3 2024: $4.7BQ4 2024: −$633MQ1 2025: $1.5BQ2 2025: $3.6BQ3 2025: $4.6BQ4 2025: −$5.4BQ1 2026: $1.8BQ2 2026: $6.3B
Q3 2023: $4.5BQ4 2023: −$1BQ1 2024: $788MQ2 2024: $5.5BQ3 2024: $4.7BQ4 2024: −$633MQ1 2025: $1.5BQ2 2025: $3.6BQ3 2025: $4.6BQ4 2025: −$5.4BQ1 2026: $1.8BQ2 2026: $6.3B
QuarterFree cash flowYoY
Q2 2026$6.3B+73%
Q1 2026$1.8B+20%
Q4 2025-$5.4B-$4.7B
Q3 2025$4.6B-2.1%
Q2 2025$3.6B-34%
Q1 2025$1.5B+89%
Q4 2024-$632.6M+$390.5M
Q3 2024$4.7B+3.3%

NVO has the edge over ACIU on cash generation, producing positive trailing cash flow while its opponent burns cash.

ACIU Total Shares

Q3 2023: 84MQ4 2023: 84MQ1 2024: 99MQ2 2024: 100MQ3 2024: 101MQ4 2024: 101MQ1 2025: 100MQ2 2025: 101MQ3 2025: 99MQ4 2025: 101MQ1 2026: 99MQ2 2026: 99M
Q3 2023: 84MQ4 2023: 84MQ1 2024: 99MQ2 2024: 100MQ3 2024: 101MQ4 2024: 101MQ1 2025: 100MQ2 2025: 101MQ3 2025: 99MQ4 2025: 101MQ1 2026: 99MQ2 2026: 99M
PeriodChange %Net change
Quarterly0%--
1 year-1.9%-2M shares
3 years+17%+14.5M shares
5 years+34%+25M shares
Available history+37%+26.4M shares

ACIU has the edge over NVO on shareholder dilution, with a more favorable share count trend.

NVO Total Shares

Q3 2023: 4.5BQ4 2023: 4.5BQ1 2024: 4.5BQ2 2024: 4.5BQ3 2024: 4.5BQ4 2024: 4.5BQ1 2025: 4.4BQ2 2025: 4.4BQ3 2025: 4.4BQ4 2025: 4.4BQ1 2026: 4.4BQ2 2026: 4.4B
Q3 2023: 4.5BQ4 2023: 4.5BQ1 2024: 4.5BQ2 2024: 4.5BQ3 2024: 4.5BQ4 2024: 4.5BQ1 2025: 4.4BQ2 2025: 4.4BQ3 2025: 4.4BQ4 2025: 4.4BQ1 2026: 4.4BQ2 2026: 4.4B
PeriodChange %Net change
Quarterly-0.3%-12.9M shares
1 year-0.2%-11M shares
3 years-1.5%-66.8M shares
5 years-3.8%-177M shares
Available history-6.5%-311M shares

NVO has 4.4B diluted shares, about the same as a year ago.

ACIU Net Leverage

QuarterNet LeverageStatus
Q4 2019-4.3xNet Cash
Q3 2019-4.3xNet Cash

ACIU has more cash than debt.

NVO Net Leverage

Q3 2023: -0.0xQ4 2023: 0.1xQ1 2024: 0.2xQ2 2024: 0.0xQ3 2024: -0.0xQ4 2024: 0.6xQ1 2025: 0.5xQ2 2025: 0.5xQ3 2025: 0.4xQ4 2025: 0.6xQ1 2026: 0.7xQ2 2026: 0.5x
Q3 2023: -0.0xQ4 2023: 0.1xQ1 2024: 0.2xQ2 2024: 0.0xQ3 2024: -0.0xQ4 2024: 0.6xQ1 2025: 0.5xQ2 2025: 0.5xQ3 2025: 0.4xQ4 2025: 0.6xQ1 2026: 0.7xQ2 2026: 0.5x
QuarterNet LeverageStatus
Q2 20260.5xVery low
Q1 20260.7xVery low
Q4 20250.6xVery low
Q3 20250.4xVery low
Q2 20250.5xVery low
Q1 20250.5xVery low
Q4 20240.6xVery low
Q3 2024-0.0xVery low

NVO's net debt is less than a year of its operating earnings (EBITDA).

ACIU Weekly Momentum

MetricValueStatus
RSI40.0Neutral
Stochastic18.0Oversold

ACIU's weekly RSI is 40 (neutral) and its Stochastic is 18 (oversold).

NVO Weekly Momentum

MetricValueStatus
RSI43.0Neutral
Stochastic27.0Neutral

NVO's weekly RSI is 43 (neutral) and its Stochastic is 27 (neutral).

ACIU PE vs Healthcare Sector

MetricACIUSector medianRelative
PEN/A26x—

ACIU has no meaningful PE right now: it lost money over the past year.

NVO PE vs Healthcare Sector

MetricNVOSector medianRelative
PE10x26x60% below
PE %62923 pts below

NVO is trading at 10x earnings, a 60% discount to the Healthcare sector's median of 26x, though its earnings don't support one.

ACIU Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$2.3910% below
20 week MA$2.4713% below
50 week MA$2.7422% below
100 week MA$2.5717% below
200 week MA$2.8124% below

ACIU is in a downtrend: it's below all five of its weekly moving averages, and 24% below its 200-week average.

NVO Weekly Moving Averages

Moving averageMA priceRelative
8 week MA$39.23.7% above
20 week MA$43.97.4% below
50 week MA$45.310% below
100 week MA$56.328% below
200 week MA$80.750% below

NVO has the edge over ACIU on trend strength, trading above more of its moving averages.

ACIU Yearly ROI

YearStart priceEnd priceROI
2020$8.39$5.51-34%
2021$5.51$5.39-2.2%
2022$5.39$1.75-68%
2023$1.75$5.00+186%
2024$5.00$2.73-45%
2025$2.73$3.13+15%
2026 YTD$3.13$2.14-32%

ACIU's yearly returns have swung widely, from +186% in 2023 to −68% in 2022. It's down 32% so far in 2026.

NVO Yearly ROI

YearStart priceEnd priceROI
2020$29.1$34.7+19%
2021$34.7$54.2+56%
2022$54.2$67.0+24%
2023$67.0$103.5+54%
2024$103.5$87.4-16%
2025$87.4$52.4-40%
2026 YTD$52.4$40.7-22%

NVO has the edge over ACIU on returns for 2026, with the stronger performance.

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